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Home/Compounds/CAS 264622-58-4
Formula C26H26N6O4MW 486.5Research-use catalog entryCOA/SDS by request

Mrs-1754

CAS Number: 264622-58-4

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Loading RDKit molecule structure...
InChIKey: AJBBEYXFRYFVNM-UHFFFAOYSA-NC26H26N6O4 | MW 486.5

Chemical Absolute Identifiers

CAS Number

264622-58-4

PubChem CID

6603931

Molecular Formula

C26H26N6O4

Molecular Weight

486.5 g/mol

Exact Mass

486.201553

InChIKey

AJBBEYXFRYFVNM-UHFFFAOYSA-N

IUPAC Name

N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide

SMILES String

CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C#N)cc4)cc3)nc2n(CCC)c1=O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Mrs-1754 (CAS 264622-58-4) is listed in the Advanced Chemicals portfolio, with molecular formula C26H26N6O4 and molecular weight 486. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Adenosine receptor A2b (Homo sapiens) — 19 assays; Adenosine receptor A2a (Homo sapiens) — 12 assays; Adenosine receptor A2b (Mus musculus) — 2 assays; Adenosine receptor A2b (Rattus norvegicus) — 3 assays; Adenosine receptor A1 (Rattus norvegicus) — 5 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Adenosine receptor A2b

Homo sapiens · SINGLE PROTEIN · 19 qualifying assays · 18 documents · best pChEMBL 8.72

Experimental evidence source: ChEMBL

Adenosine receptor A2a

Homo sapiens · SINGLE PROTEIN · 12 qualifying assays · 12 documents · best pChEMBL 8.71

Experimental evidence source: ChEMBL

Adenosine receptor A2b

Mus musculus · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 8.51

Experimental evidence source: ChEMBL

Adenosine receptor A2b

Rattus norvegicus · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 7.89

Experimental evidence source: ChEMBL

Adenosine receptor A1

Rattus norvegicus · SINGLE PROTEIN · 5 qualifying assays · 5 documents · best pChEMBL 7.78

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Mrs-1754

Names & Synonyms

MRS 1754N-(4-cyanophenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy)acetamideN-(4-Cyanophenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)phenoxy)acetamide[3H]MRS1754N-(4-Cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide
Show all synonyms
Acetamide, N-(4-cyanophenyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy]acetamideAcetamide, N-(4-cyanophenyl)-2-(4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy)-Acetamide, N-(4-cyanophenyl)-2-(4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy)-N-(4-cyanophenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)acetamide[3H]-MRS1754Lopac-M-6316Lopac0_000729MRS1754?s6693M 63168-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate(4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl ester
External Identifiers
EC NUMBER: 806-672-9DSSTOX SUBSTANCE ID: DTXSID80424967CHEMBL ID: CHEMBL273807CHEBI ID: CHEBI:93269UNII: 7E435V2DAHHMDB ID: HMDB0254927WIKIDATA ID: Q27087766
Literature & Patent References
DOI 10.6019/CHEMBL5665443Enzyme Inhibitor Single Concentration assay results for EUbOPEN Chemogenomics LibraryDOI 10.6019/CHEMBL5209801GPCR results for EUbOPEN Chemogenomics Library 3DOI 10.1016/j.ejmech.2021.113907Adenosine receptor antagonists: Recent advances and therapeutic perspective.DOI 10.6019/CHEMBL5058564Tm Shift (DSF) assay results for EUbOPEN Chemogenomis Library 2 (Incucyte)PMID 34695776Adenosine receptor antagonists: Recent advances and therapeutic perspective.DOI 10.1021/acs.jmedchem.0c014313,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition.DOI 10.1021/acs.jmedchem.1c00261The Medicinal Chemistry of Caffeine.PMID 333728003,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

DpcpxCAS 102146-07-6

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 102146-07-6DpcpxCAS 75706-12-6LeflunomideCAS 879085-55-9VismodegibCAS 58-61-7AdenosineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 264622-58-4

What are the key identifiers for Mrs-1754 (CAS 264622-58-4)?

Mrs-1754 is identified by CAS 264622-58-4, with molecular formula C26H26N6O4, molecular weight 486.5, InChIKey AJBBEYXFRYFVNM-UHFFFAOYSA-N.

Does CAS 264622-58-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Adenosine receptor A2b, Adenosine receptor A2a, Adenosine receptor A2b, Adenosine receptor A2b, Adenosine receptor A1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 264622-58-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Mrs-1754?

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Is CAS 264622-58-4 available for quotation?

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