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Home/Compounds/CAS 29216-28-2
Formula C20H22N2SMW 322.5Research-use catalog entryCOA/SDS by request

Mequitazine

CAS Number: 29216-28-2

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1 g
Purity
98%
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10 g
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100 mg
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250 mg
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Loading RDKit molecule structure...
InChIKey: HOKDBMAJZXIPGC-UHFFFAOYSA-NC20H22N2S | MW 322.5

Chemical Absolute Identifiers

CAS Number

29216-28-2

PubChem CID

4066

Molecular Formula

C20H22N2S

Molecular Weight

322.5 g/mol

Exact Mass

322.15037

InChIKey

HOKDBMAJZXIPGC-UHFFFAOYSA-N

IUPAC Name

10-(1-azabicyclo[2.2.2]octan-3-ylmethyl)phenothiazine

SMILES String

C1CN2CCC1C(C2)CN3C4=CC=CC=C4SC5=CC=CC=C53

Physical Properties

Melting Point

130.5 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Mequitazine (CAS 29216-28-2) is listed in the Advanced Chemicals portfolio, with molecular formula C20H22N2S and molecular weight 322. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Histamine H1 receptor (Cavia porcellus) — 2 assays; Muscarinic acetylcholine receptor M2 (Homo sapiens) — 2 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 2 assays; 5-hydroxytryptamine receptor 2B (Homo sapiens) — 2 assays; 5-hydroxytryptamine receptor 2A (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Histamine H1 receptor

Cavia porcellus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 9

Experimental evidence source: ChEMBL

Muscarinic acetylcholine receptor M2

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 7.17

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.46

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2B

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.51

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2A

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.42

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.
  • Avoid contact with skin and eyes.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Mequitazine

Names & Synonyms

KitazeminMequitazinaMequitazinum10-(3-Quinuclidinylmethyl)phenothiazine3-Methylquinuclidinyl-10-phenothiazine
Show all synonyms
Quitadrill10-(1-azabicyclo(2.2.2)octan-3-ylmethyl)-10H-phenothiazine10-{1-azabicyclo[2.2.2]octan-3-ylmethyl}-10H-phenothiazine10-(1-azabicyclo(2.2.2)oct-8-ylmethyl)phenothiazine10-((3RS)-1-Azabicyclo(2.2.2)oct-3-ylmethyl)-10H-phenothiazineVirginanMetaplexanPrimalanMircolInstotalVigiganZesulan10-(1-Azabicyclo[2.2.2]oct-3-ylmethyl)-10H-phenothiazineMequitazina [Spanish]10-(Quinuclidin-3-ylmethyl)-10H-phenothiazine
External Identifiers
EC NUMBER: 249-521-7DSSTOX SUBSTANCE ID: DTXSID8023262CHEMBL ID: CHEMBL73451CHEBI ID: CHEBI:31821UNII: Y463242LY2DRUGBANK ID: DB01071HMDB ID: HMDB0015204KEGG ID: C12755KEGG ID: D01324METABOLOMICS WORKBENCH ID: 43307NCI THESAURUS CODE: C170162PHARMGKB ID: PA164748010WIKIDATA ID: Q3333256
Experimental Spectrum References
13C NMR Spectra1H NMR Spectra
Literature & Patent References
DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.1101/2020.03.20.999730Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugsDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortDOI 10.1021/jm8008663Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Fenethazine hydrochlorideCAS 5934-20-3
sodium 3-phenothiazin-10-ylpropane-1-sulfonateCAS 101199-38-6
10-PhenylphenothiazineCAS 7152-42-3
10H-phenothiazine-3-methanol, 10-methyl-CAS 17800-45-2
12-Phenyl-12h-benzo[b]phenothiazineCAS 1320277-85-7

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 128-13-2Ursodeoxycholic AcidCAS 21829-25-4NifedipineCAS 319460-85-0AxitinibCAS 100643-71-8DesloratadineCAS 102767-28-2LevetiracetamCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 29216-28-2

What are the key identifiers for Mequitazine (CAS 29216-28-2)?

Mequitazine is identified by CAS 29216-28-2, with molecular formula C20H22N2S, molecular weight 322.5, InChIKey HOKDBMAJZXIPGC-UHFFFAOYSA-N.

Does CAS 29216-28-2 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Histamine H1 receptor, Muscarinic acetylcholine receptor M2, Alpha-1A adrenergic receptor, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2A. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 29216-28-2?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Mequitazine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 29216-28-2 available for quotation?

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