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Home/Compounds/CAS 29342-05-0
Formula C12H17NO2MW 207.27Research-use catalog entryCOA/SDS by request

Ciclopirox

CAS Number: 29342-05-0

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Loading RDKit molecule structure...
InChIKey: SCKYRAXSEDYPSA-UHFFFAOYSA-NC12H17NO2 | MW 207.27

Chemical Absolute Identifiers

CAS Number

29342-05-0

PubChem CID

2749

Molecular Formula

C12H17NO2

Molecular Weight

207.27 g/mol

Exact Mass

207.125929

InChIKey

SCKYRAXSEDYPSA-UHFFFAOYSA-N

IUPAC Name

6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one

SMILES String

CC1=CC(=O)N(C(=C1)C2CCCCC2)O

Physical Properties

Melting Point

144.0 °C

Water Solubility

1.41 g/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Ciclopirox (CAS 29342-05-0) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C12H17NO2 and molecular weight 207. 27 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Alpha-1A adrenergic receptor (Homo sapiens) — 3 assays; Nuclear receptor subfamily 1 group I member 2 (Homo sapiens) — 2 assays; Muscarinic acetylcholine receptor M1 (Homo sapiens) — 2 assays; Muscarinic acetylcholine receptor M2 (Homo sapiens) — 3 assays; Progesterone receptor (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 4.64

Experimental evidence source: ChEMBL

Nuclear receptor subfamily 1 group I member 2

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.58

Experimental evidence source: ChEMBL

Muscarinic acetylcholine receptor M1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.55

Experimental evidence source: ChEMBL

Muscarinic acetylcholine receptor M2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Progesterone receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional institution with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus during firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Ciclopirox

Names & Synonyms

LoproxPenlacHOE 296bCiclopiroxum2(1H)-Pyridinone, 6-cyclohexyl-1-hydroxy-4-methyl-
Show all synonyms
cyclopirox6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinoneCiclodanCNL82(1H)-Pyridone, 6-cyclohexyl-1-hydroxy-4-methyl-6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-oneDafnegin CSCCiclopiroxolamine6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-oneCiclopiroxum [INN-Latin]6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridoneCiclopirox (Penlac)Loprox (TN)
External Identifiers
EC NUMBER: 249-577-2DSSTOX SUBSTANCE ID: DTXSID9048564CHEMBL ID: CHEMBL1413CHEBI ID: CHEBI:453011UNII: 19W019ZDRJDRUGBANK ID: DB01188HMDB ID: HMDB0015319KEGG ID: D03488METABOLOMICS WORKBENCH ID: 43404NCI THESAURUS CODE: C61677PHARMGKB ID: PA164747060RXCUI: 21090WIKIDATA ID: Q419468HOE-296b
Experimental Spectrum References
13C NMR Spectra1H NMR SpectraFTIR SpectraUV-VIS Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2024.117093Recent advances in screening methods enabling the discovery of novel anti-hepatitis B virus drug candidates.PMID 39612566Recent advances in screening methods enabling the discovery of novel anti-hepatitis B virus drug candidates.DOI 10.1016/j.ejmech.2024.116833Drug repurposing against antibiotic resistant bacterial pathogens.DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1021/acs.jmedchem.4c01183Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay.PMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 39018123Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay.PMID 39243454Drug repurposing against antibiotic resistant bacterial pathogens.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Ciclopirox OlamineCAS 41621-49-2

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 41621-49-2Ciclopirox OlamineCAS 2719-27-9Cyclohexanecarbonyl chlorideCAS 102767-28-2LevetiracetamCAS 134678-17-4LamivudineCAS 155270-99-8IstradefyllineCAS 21829-25-4NifedipineCAS 27220-47-9EconazoleCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 29342-05-0

What are the key identifiers for Ciclopirox (CAS 29342-05-0)?

Ciclopirox is identified by CAS 29342-05-0, with molecular formula C12H17NO2, molecular weight 207.27, InChIKey SCKYRAXSEDYPSA-UHFFFAOYSA-N.

Does CAS 29342-05-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Alpha-1A adrenergic receptor, Nuclear receptor subfamily 1 group I member 2, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M2, Progesterone receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 29342-05-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Ciclopirox?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 29342-05-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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