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Home/Compounds/CAS 29676-71-9
Formula C5H6N2O2SMW 158.18Research-use catalog entryCOA/SDS by request

(2-Amino-1,3-thiazol-4-yl)acetic acid

CAS Number: 29676-71-9

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Loading RDKit molecule structure...
InChIKey: DYCLHZPOADTVKK-UHFFFAOYSA-NC5H6N2O2S | MW 158.18

Chemical Absolute Identifiers

CAS Number

29676-71-9

PubChem CID

34665

Molecular Formula

C5H6N2O2S

Molecular Weight

158.18 g/mol

Exact Mass

158.014999

InChIKey

DYCLHZPOADTVKK-UHFFFAOYSA-N

IUPAC Name

2-(2-amino-1,3-thiazol-4-yl)acetic acid

SMILES String

C1=C(N=C(S1)N)CC(=O)O

Physical Properties

Appearance

2-amino-4-thiazole acetic acid is a light orange powder. (NTP, 1992)

Water Solubility

1 mol/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

(2-Amino-1,3-thiazol-4-yl)acetic acid (CAS 29676-71-9) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C5H6N2O2S and molecular weight 158. 18 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2 (Homo sapiens) — 2 assays; UDP-N-acetylglucosamine 1-carboxyvinyltransferase (Escherichia coli K-12) — 3 assays; Replicase polyprotein 1ab (Severe acute respiratory syndrome coronavirus 2) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2

Homo sapiens · PROTEIN COMPLEX · 2 qualifying assays · 1 documents · best pChEMBL 4.62

Experimental evidence source: ChEMBL

UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Escherichia coli K-12 · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Replicase polyprotein 1ab

Severe acute respiratory syndrome coronavirus 2 · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.
  • Avoid contact with skin and eyes.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Stability and reactivity.
  • Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

(2-Amino-1,3-thiazol-4-yl)acetic acid

Names & Synonyms

2-AMINO-4-THIAZOLEACETIC ACID2-(2-Aminothiazol-4-yl)acetic acid2-Aminothiazol-4-acetic acid4-Thiazoleacetic acid, 2-amino-(2-Aminothiazole-4-yl)acetic acid
Show all synonyms
2-Aminothiazole-4-acetic acid(2-Amino-4-thiazolyl)acetic acid2-amino-4-thiazolylacetic acid2-AMINOTHIAZOL-4-YLACETIC ACID2-amino-4-thiazole acetic acid(2-Aminothiazole-4-YL)-Acetic Acid2-(2-Aminothiazol-4-yl) acetic acid2-Amino-4-thiazoleaceticacid2-Amino-4-thiazoleaetic acid2-aminothiazol-4-yl-acetic acid(2-aminothiazol-4-yl)acetic acid2-(2-Aminothiazol-4-yl)aceticacid(2-amino-thiazol-4-yl)-acetic acid2-(2-Aminothiazole-4-Yl) Acetic Acid
External Identifiers
EC NUMBER: 249-769-6DSSTOX SUBSTANCE ID: DTXSID0024509CHEMBL ID: CHEMBL71460UNII: QSH3O4TNJT
Experimental Spectrum References
13C NMR SpectraATR-IR SpectraFTIR Spectra — Sigma-Aldrich Co. LLC.Raman Spectra
Literature & Patent References
DOI 10.1021/acsmedchemlett.2c00429Fragment-Sized Thiazoles in Fragment-Based Drug Discovery Campaigns: Friend or Foe?PMID 36518695Fragment-Sized Thiazoles in Fragment-Based Drug Discovery Campaigns: Friend or Foe?DOI 10.1021/acs.jmedchem.9b00026Five-Membered N-Heterocyclic Scaffolds as Novel Amino Bioisosteres at γ-Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters.PMID 31117514Five-Membered N-Heterocyclic Scaffolds as Novel Amino Bioisosteres at γ-Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters.DOI 10.1021/jm00395a008Aryl diazo compounds and diazonium salts as potential irreversible probes of the gamma-aminobutyric acid receptor.PMID 2824775Aryl diazo compounds and diazonium salts as potential irreversible probes of the gamma-aminobutyric acid receptor.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

(2-Amino-1,3-thiazol-4-yl)acetic acid--hydrogen chloride (1/1)CAS 66659-20-9
(2-Benzylamino-thiazol-4-yl)-acetic acidCAS 211102-84-0
MirabegronCAS 223673-61-8

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 66659-20-9(2-Amino-1,3-thiazol-4-yl)acetic acid--hydrogen chloride (1/1)CAS 211102-84-0(2-Benzylamino-thiazol-4-yl)-acetic acidCAS 223673-61-8MirabegronCAS 10444-89-01,3,4-Thiadiazol-2-amine, 5-(trifluoromethyl)-CAS 108-33-81,3,4-Thiadiazole, 2-amino-5-methyl-CAS 170235-26-4Methyl 2-bromothiazole-4-carboxylateCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 29676-71-9

What are the key identifiers for (2-Amino-1,3-thiazol-4-yl)acetic acid (CAS 29676-71-9)?

(2-Amino-1,3-thiazol-4-yl)acetic acid is identified by CAS 29676-71-9, with molecular formula C5H6N2O2S, molecular weight 158.18, InChIKey DYCLHZPOADTVKK-UHFFFAOYSA-N.

Does CAS 29676-71-9 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Replicase polyprotein 1ab. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 29676-71-9?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for (2-Amino-1,3-thiazol-4-yl)acetic acid?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

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