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Home/Compounds/CAS 29908-03-0
Formula C15H22N6O5SMW 398.4Research-use catalog entryCOA/SDS by request

S-Adenosylmethionine

CAS Number: 29908-03-0

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Available Options

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1 g
Purity
98%
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250 mg
Purity
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Loading RDKit molecule structure...
InChIKey: MEFKEPWMEQBLKI-AIRLBKTGSA-NC15H22N6O5S | MW 398.4

Chemical Absolute Identifiers

CAS Number

29908-03-0

PubChem CID

34755

Molecular Formula

C15H22N6O5S

Molecular Weight

398.4 g/mol

Exact Mass

398.137239

InChIKey

MEFKEPWMEQBLKI-AIRLBKTGSA-N

IUPAC Name

(2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate

SMILES String

C[S+](CC[C@@H](C(=O)[O-])N)C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O

Physical Properties

Boiling Point

78.0 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

S-Adenosylmethionine (CAS 29908-03-0) is listed in the Advanced Chemicals portfolio, with molecular formula C15H22N6O5S and molecular weight 398. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Histone-arginine methyltransferase CARM1 (Homo sapiens) — 2 assays; Met repressor (Escherichia coli) — 2 assays; Protein arginine N-methyltransferase 1 (Homo sapiens) — 2 assays; Phenylethanolamine N-methyltransferase (Homo sapiens) — 6 assays; S-adenosylmethionine decarboxylase proenzyme (Rattus norvegicus) — 9 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Histone-arginine methyltransferase CARM1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 8.55

Experimental evidence source: ChEMBL

Met repressor

Escherichia coli · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 8.4

Experimental evidence source: ChEMBL

Protein arginine N-methyltransferase 1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.33

Experimental evidence source: ChEMBL

Phenylethanolamine N-methyltransferase

Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 1 documents · best pChEMBL 5.32

Experimental evidence source: ChEMBL

S-adenosylmethionine decarboxylase proenzyme

Rattus norvegicus · SINGLE PROTEIN · 9 qualifying assays · 2 documents · best pChEMBL 4.22

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Including any incompatibility.
  • Close tightly.
  • Store in a well-ventilated area.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and stability.
  • Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

S-Adenosylmethionine

Names & Synonyms

Active methionineS-adenosyl methionineAdenosine, 5'-((3-amino-3-carboxypropyl)methylsulfonio)-5'-deoxy-, inner salt, (3S)-S-adenosyl-methionineS Adenosylmethionine
Show all synonyms
S Adenosyl L Methionine((3R)-3-amino-3-carboxypropyl)((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl)methyl))methylsulfanium((3S)-3-amino-3-carboxypropyl)((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl)methyl))methylsulfaniumS Adenosylmethionine Sulfate TosylateFO 15615'-((3-Amino-3-carboxypropyl)methylsulfonio)-5'-deoxyadenosine Hydroxide, Inner SaltS-adenosyl-L-methionineAdemetionineSAMeSAM-eadenosylmethionineMethioninyladenylateL-S-AdenosylmethionineAdemetionine, (S)-S Amet
External Identifiers
EC NUMBER: 249-946-8DSSTOX SUBSTANCE ID: DTXSID6032019CHEMBL ID: CHEMBL1088977CHEMBL ID: CHEMBL1235831CHEBI ID: CHEBI:67040UNII: 6EZ5466ZUXUNII: 7LP2MPO46SUNII: K093C397ULDRUGBANK ID: DB00118KEGG ID: C00019KEGG ID: C22529METABOLOMICS WORKBENCH ID: 121951METABOLOMICS WORKBENCH ID: 37647NCI THESAURUS CODE: C100098NCI THESAURUS CODE: C63661PHARMGKB ID: PA164754994RXCUI: 9504WIKIDATA ID: Q27135598
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c01548Design, Synthesis, and Biological Evaluation of 3,4-Dihydroisoquinolin-1(<i>2H</i>)-one Derivatives as Protein Arginine Methyltransferase 5 Inhibitors for the Treatment of Non-Hodgkin's Lymphoma.DOI 10.1021/acs.jmedchem.4c02106Small-Molecule Modulators Targeting Coactivator-Associated Arginine Methyltransferase 1 (CARM1) as Therapeutic Agents for Cancer Treatment: Current Medicinal Chemistry Insights and Emerging Opportunities.DOI 10.1021/acs.jmedchem.5c00339Electrostatic Anchoring in RNA-Ligand Design─Dissecting the Effects of Positive Charges on Affinity, Selectivity, Binding Kinetics, and Thermodynamics.PMID 39506904Small-Molecule Modulators Targeting Coactivator-Associated Arginine Methyltransferase 1 (CARM1) as Therapeutic Agents for Cancer Treatment: Current Medicinal Chemistry Insights and Emerging Opportunities.PMID 39722476Design, Synthesis, and Biological Evaluation of 3,4-Dihydroisoquinolin-1(<i>2H</i>)-one Derivatives as Protein Arginine Methyltransferase 5 Inhibitors for the Treatment of Non-Hodgkin's Lymphoma.PMID 40191889Electrostatic Anchoring in RNA-Ligand Design─Dissecting the Effects of Positive Charges on Affinity, Selectivity, Binding Kinetics, and Thermodynamics.DOI 10.1016/j.ejmech.2023.115290Recent advances in the development of methyltransferase (MTase) inhibitors against (re)emerging arboviruses diseases dengue and Zika.DOI 10.1021/acs.jnatprod.3c00330Heterolactone and Heterolactams A-M, Verticillane Diterpenoids with Anti-Inflammatory and Hepatoprotective Activities from the Soft Coral <i>Heteroxenia ghardaqensis</i>.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

S-(5'-Adenosyl)-L-methionine chloride dihydrochlorideCAS 86867-01-8
VidarabineCAS 5536-17-4
9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-, hydrate (1:1)CAS 24356-66-9
5'-Chloro-5'-deoxyadenosineCAS 892-48-8
5'-Deoxy-5'-fluoroadenosineCAS 731-98-6

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 86867-01-8S-(5'-Adenosyl)-L-methionine chloride dihydrochlorideCAS 5536-17-4VidarabineCAS 24356-66-99H-Purin-6-amine, 9-beta-D-arabinofuranosyl-, hydrate (1:1)CAS 892-48-85'-Chloro-5'-deoxyadenosineCAS 731-98-65'-Deoxy-5'-fluoroadenosineCAS 979-92-0AdenosylhomocysteineCAS 100-33-4PentamidineCAS 100643-71-8DesloratadineCAS 102767-28-2LevetiracetamCAS 58-61-7Adenosine

RFQ questions for CAS 29908-03-0

What are the key identifiers for S-Adenosylmethionine (CAS 29908-03-0)?

S-Adenosylmethionine is identified by CAS 29908-03-0, with molecular formula C15H22N6O5S, molecular weight 398.4, InChIKey MEFKEPWMEQBLKI-AIRLBKTGSA-N.

Does CAS 29908-03-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Histone-arginine methyltransferase CARM1, Met repressor, Protein arginine N-methyltransferase 1, Phenylethanolamine N-methyltransferase, S-adenosylmethionine decarboxylase proenzyme. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 29908-03-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for S-Adenosylmethionine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 29908-03-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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