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Home/Compounds/CAS 313-04-2
Formula C27H44OMW 384.6Research-use catalog entryCOA/SDS by request

Desmosterol

CAS Number: 313-04-2

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Loading RDKit molecule structure...
InChIKey: AVSXSVCZWQODGV-DPAQBDIFSA-NC27H44O | MW 384.6

Chemical Absolute Identifiers

CAS Number

313-04-2

PubChem CID

439577

Molecular Formula

C27H44O

Molecular Weight

384.6 g/mol

Exact Mass

384.339216

InChIKey

AVSXSVCZWQODGV-DPAQBDIFSA-N

IUPAC Name

(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

SMILES String

C[C@H](CCC=C(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C

Physical Properties

Melting Point

121.5 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Desmosterol (CAS 313-04-2) is listed in the Inhibitors and Agonists portfolio, with molecular formula C27H44O and molecular weight 384. 60 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for biochemical and pharmacology research workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Bioactivity ScreeningResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Nuclear receptor ROR-gamma (Homo sapiens) — 7 assays; Steroid C26-monooxygenase (Mycobacterium tuberculosis) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Nuclear receptor ROR-gamma

Homo sapiens · SINGLE PROTEIN · 7 qualifying assays · 3 documents · best pChEMBL 7.32

Experimental evidence source: ChEMBL

Steroid C26-monooxygenase

Mycobacterium tuberculosis · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

Desmosterol

Names & Synonyms

24-Dehydrocholesteroldesmesterolcholest-5,24-dien-3beta-olCholesta-5,24-dien-3-ol, (3beta)-Demosterol
Show all synonyms
24 Dehydrocholesterol(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((2R)-6-methylhept-5-en-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-3-ol3beta-cholesta-5,24-dien-3-ol(3beta)-Cholesta-5,24-dien-3-olCholesta-5,24-dien-3-ol, (3.beta.)-(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylhept-5-en-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-olCholesta-5,24-dien-3-ol3b-Cholesta-5,24-dien-3-ol3|A-Hydroxy-5,24-cholestadieneMHQ(3|A)-Cholesta-5,24-dien-3-olDESMOSTEROL [MI]Cholesta-5,24-dien-3b-olDesmosterol, >=84% (GC)
External Identifiers
EC NUMBER: 206-236-2DSSTOX SUBSTANCE ID: DTXSID10878676CHEMBL ID: CHEMBL455876CHEBI ID: CHEBI:17737UNII: ANP93865R8HMDB ID: HMDB0002719KEGG ID: C01802METABOLOMICS WORKBENCH ID: 34376WIKIDATA ID: Q3024529
Experimental Spectrum References
13C NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR Spectra — Forensic Spectral ResearchRaman Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c01727Discovery of 1-(Phenylsulfonyl)-1,2,3,4-tetrahydroquinoline Derivative as Orally Bioavailable and Safe RORγt Inverse Agonists for Potential Treatment of Rheumatoid Arthritis.PMID 39546350Discovery of 1-(Phenylsulfonyl)-1,2,3,4-tetrahydroquinoline Derivative as Orally Bioavailable and Safe RORγt Inverse Agonists for Potential Treatment of Rheumatoid Arthritis.DOI 10.1021/acsmedchemlett.1c00029Covalent Occlusion of the RORγt Ligand Binding Pocket Allows Unambiguous Targeting of an Allosteric Site.PMID 33854703Covalent Occlusion of the RORγt Ligand Binding Pocket Allows Unambiguous Targeting of an Allosteric Site.DOI 10.1021/acs.jmedchem.7b01314Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Agonists as Potential Small Molecule Therapeutics for Cancer Immunotherapy.PMID 29412659Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Agonists as Potential Small Molecule Therapeutics for Cancer Immunotherapy.DOI 10.1016/j.bmc.2013.07.015Synthesis and biological activity of (24E)- and (24Z)-26-hydroxydesmosterol.PMID 23910990Synthesis and biological activity of (24E)- and (24Z)-26-hydroxydesmosterol.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Dehydrolithocholic AcidCAS 1553-56-6

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 57-88-5CholesterolCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 313-04-2

What are the key identifiers for Desmosterol (CAS 313-04-2)?

Desmosterol is identified by CAS 313-04-2, with molecular formula C27H44O, molecular weight 384.6, InChIKey AVSXSVCZWQODGV-DPAQBDIFSA-N.

Does CAS 313-04-2 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Nuclear receptor ROR-gamma, Steroid C26-monooxygenase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 313-04-2?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Desmosterol?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 313-04-2 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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