- Package
- 1 g
- Purity
- 98%
- Price
- Request review
- Availability
- Shipping review required
- Delivery
- Shipping review required
CAS Number: 319460-85-0
Submit an RFQ to review pricing, availability, lead time, pack size, purity, COA, and supplier SDS for this catalog entry.
Available options
Shipping review is required before pricing or stock can be confirmed publicly. Shipping, duties, and documentation fees are confirmed before order acceptance.
CAS Number
319460-85-0
PubChem CID
6450551
Molecular Formula
C22H18N4OS
Molecular Weight
386.5 g/mol
Exact Mass
386.120132
InChIKey
RITAVMQDGBJQJZ-FMIVXFBMSA-N
IUPAC Name
N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide
SMILES String
CNC(=O)c1ccccc1Sc1ccc2c(/C=C/c3ccccn3)n[nH]c2c1
Water Solubility
1.1 mol/L
pKa
4.8
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Axitinib (CAS 319460-85-0) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C22H18N4OS and molecular weight 386. 50 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: Vascular endothelial growth factor receptor 2 (Homo sapiens) — 13 assays; Vascular endothelial growth factor receptor 1 (Homo sapiens) — 4 assays; Vascular endothelial growth factor receptor 3 (Homo sapiens) — 4 assays; Tyrosine-protein kinase ABL1 (Homo sapiens) — 27 assays; Mast/stem cell growth factor receptor Kit (Homo sapiens) — 27 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Vascular endothelial growth factor receptor 2
Homo sapiens · SINGLE PROTEIN · 13 qualifying assays · 12 documents · best pChEMBL 10.7
Experimental evidence source: ChEMBL
Vascular endothelial growth factor receptor 1
Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 4 documents · best pChEMBL 10
Experimental evidence source: ChEMBL
Vascular endothelial growth factor receptor 3
Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 4 documents · best pChEMBL 10
Experimental evidence source: ChEMBL
Tyrosine-protein kinase ABL1
Homo sapiens · SINGLE PROTEIN · 27 qualifying assays · 5 documents · best pChEMBL 9.7
Experimental evidence source: ChEMBL
Mast/stem cell growth factor receptor Kit
Homo sapiens · SINGLE PROTEIN · 27 qualifying assays · 5 documents · best pChEMBL 9.31
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.
Preliminary Safety Reference
For supplier-issued SDS or COA, submit a documentation request.
Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Axitinib is identified by CAS 319460-85-0, with molecular formula C22H18N4OS, molecular weight 386.5, InChIKey RITAVMQDGBJQJZ-FMIVXFBMSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Vascular endothelial growth factor receptor 2, Vascular endothelial growth factor receptor 1, Vascular endothelial growth factor receptor 3, Tyrosine-protein kinase ABL1, Mast/stem cell growth factor receptor Kit. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
Availability, pack size, lead time, and pricing are confirmed through RFQ.
Submit the CAS number, quantity, purity requirement, and destination country for sourcing review.