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Home/Compounds/CAS 320-67-2
Formula C8H12N4O5MW 244.2Research-use catalog entryCOA/SDS by request

Azacytidine

CAS Number: 320-67-2

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Loading RDKit molecule structure...
InChIKey: NMUSYJAQQFHJEW-KVTDHHQDSA-NC8H12N4O5 | MW 244.2

Chemical Absolute Identifiers

CAS Number

320-67-2

PubChem CID

9444

Molecular Formula

C8H12N4O5

Molecular Weight

244.2 g/mol

Exact Mass

244.08077

InChIKey

NMUSYJAQQFHJEW-KVTDHHQDSA-N

IUPAC Name

4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one

SMILES String

Nc1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1

Physical Properties

Appearance

5-azacytidine is a white crystalline powder. (NTP, 1992)

Melting Point

229.0 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Azacytidine (CAS 320-67-2) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C8H12N4O5 and molecular weight 244. 20 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: RecQ-like DNA helicase BLM (Homo sapiens) — 2 assays; Serine/threonine-protein kinase mTOR (Homo sapiens) — 3 assays; Prelamin-A/C (Homo sapiens) — 2 assays; Nuclear factor NF-kappa-B p105 subunit (Homo sapiens) — 2 assays; Geminin (Homo sapiens) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

RecQ-like DNA helicase BLM

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 8.8

Experimental evidence source: ChEMBL

Serine/threonine-protein kinase mTOR

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 6.93

Experimental evidence source: ChEMBL

Prelamin-A/C

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.8

Experimental evidence source: ChEMBL

Nuclear factor NF-kappa-B p105 subunit

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.65

Experimental evidence source: ChEMBL

Geminin

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents · best pChEMBL 5.5

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Azacytidine

Names & Synonyms

5-azacytidineAzacitidineLadakamycinMylosar5-azacitidine
Show all synonyms
AzacitidinaAzacitidinumAntibiotic U 18496Onureg4-Amino-1-beta-d-ribofuranosyl-1,3,5-triazin-2(1H)-one4-Amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one5 AZCU 18496U-18,4961,3,5-Triazin-2(1H)-one, 4-amino-1-beta-D-ribofuranosyl-s-Triazin-2(1H)-one, 4-amino-1-beta-D-ribofuranosyl-5 Azacytidine4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-oneazacitidine for
External Identifiers
EC NUMBER: 206-280-2DSSTOX SUBSTANCE ID: DTXSID9020116CHEMBL ID: CHEMBL1489CHEBI ID: CHEBI:2038UNII: M801H13NRUDRUGBANK ID: DB00928HMDB ID: HMDB0015063KEGG ID: C11262KEGG ID: D03021METABOLOMICS WORKBENCH ID: 43193NCI THESAURUS CODE: C288PHARMGKB ID: PA451996RXCUI: 1251WIKIDATA ID: Q416451
Experimental Spectrum References
13C NMR Spectra — Sigma-Aldrich Co. LLC.1D NMR Spectra1H NMR Spectra — Sigma-Aldrich Co. LLC.ATR-IR Spectra — Forensic Spectral ResearchRaman Spectra — Forensic Spectral ResearchUV Spectra
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c02391Design and Synthesis of Novel Deazapurine DNMT 1 Inhibitors with <i>In Vivo</i> Efficacy in DLBCL.PMID 40022722Design and Synthesis of Novel Deazapurine DNMT 1 Inhibitors with <i>In Vivo</i> Efficacy in DLBCL.DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.1016/j.ejmech.2021.113213HIV latency reversal agents: A potential path for functional cure?DOI 10.1021/acs.jmedchem.1c00601Emerging Therapeutic Potential of SIRT6 Modulators.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 21829-25-4NifedipineCAS 6974-32-9beta-D-Ribofuranose, 1-acetate 2,3,5-tribenzoateCAS 52523-35-0N-(Trimethylsilyl)-4-((trimethylsilyl)oxy)-1,3,5-triazin-2-amineCAS 13035-61-51,2,3,5-Tetraacetyl-beta-D-ribofuranoseCAS 23593-75-1ClotrimazoleCAS 50-65-7NiclosamideCAS 59-67-6Nicotinic AcidCAS 76824-35-6FamotidineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acid

RFQ questions for CAS 320-67-2

What are the key identifiers for Azacytidine (CAS 320-67-2)?

Azacytidine is identified by CAS 320-67-2, with molecular formula C8H12N4O5, molecular weight 244.2, InChIKey NMUSYJAQQFHJEW-KVTDHHQDSA-N.

Does CAS 320-67-2 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with RecQ-like DNA helicase BLM, Serine/threonine-protein kinase mTOR, Prelamin-A/C, Nuclear factor NF-kappa-B p105 subunit, Geminin. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 320-67-2?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Azacytidine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 320-67-2 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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