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Home/Compounds/CAS 326-45-4
Formula C8H5F3N2S2MW 250.3Research-use catalog entryCOA/SDS by request

2-Amino-6-(trifluoromethylthio)benzothiazole

CAS Number: 326-45-4

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Loading RDKit molecule structure...
InChIKey: PBRVVEXJMLEKMJ-UHFFFAOYSA-NC8H5F3N2S2 | MW 250.3

Chemical Absolute Identifiers

CAS Number

326-45-4

PubChem CID

2735964

Molecular Formula

C8H5F3N2S2

Molecular Weight

250.3 g/mol

Exact Mass

249.984625

InChIKey

PBRVVEXJMLEKMJ-UHFFFAOYSA-N

IUPAC Name

6-(trifluoromethylsulfanyl)-1,3-benzothiazol-2-amine

SMILES String

Nc1nc2ccc(SC(F)(F)F)cc2s1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

2-Amino-6-(trifluoromethylthio)benzothiazole (CAS 326-45-4) is listed in the Advanced Chemicals portfolio, with molecular formula C8H5F3N2S2 and molecular weight 250. 30 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Pteridine reductase 1 (Leishmania major) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Pteridine reductase 1

Leishmania major · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.72

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

2-Amino-6-(trifluoromethylthio)benzothiazole

Names & Synonyms

6-((Trifluoromethyl)thio)benzo[d]thiazol-2-amine6-[(trifluoromethyl)sulfanyl]-1,3-benzothiazol-2-amine2-amino-6-(trifluoromethylthio)-1,3-benzothiazole2-amino-6-(trifluoro-methylsufanyl)benzothiazole2-amino-6-(trifluoromethylsulfanyl)benzothiazole
Show all synonyms
6-Trifluoromethylsulfanyl-benzothiazol-2-ylamine2-amino-6-trifluoromethylsufanylbenzothiazole6-Trifluoromethylthio-2-benzothiazolamineUS9675591, SKA-192-amino-6-trifluoromethylthio-benzothiazole6-(trifluoromethylthio)benzothiazole-2-ylamine6-trifluoromethylthio-1,3-benzothiazol-2-amine6-(trifluoromethylthio)-1,3-benzothiazol-2-ylamineEUH
External Identifiers
EC NUMBER: 670-802-9DSSTOX SUBSTANCE ID: DTXSID30371053CHEMBL ID: CHEMBL95463WIKIDATA ID: Q72442880
Literature & Patent References
DOI 10.1021/acs.jmedchem.9b01877Metabolic and Pharmaceutical Aspects of Fluorinated Compounds.PMID 32182061Metabolic and Pharmaceutical Aspects of Fluorinated Compounds.DOI 10.1021/acs.jmedchem.8b02021Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections.PMID 30908048Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections.DOI 10.1021/jm980202uRiluzole series. Synthesis and in vivo "antiglutamate" activity of 6-substituted-2-benzothiazolamines and 3-substituted-2-imino-benzothiazolines.PMID 10425092Riluzole series. Synthesis and in vivo "antiglutamate" activity of 6-substituted-2-benzothiazolamines and 3-substituted-2-imino-benzothiazolines.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

6-Iodo-1,3-benzothiazol-2-amineCAS 16582-58-4
2-Benzothiazolamine, 6-chloro-, hydrochloride (1:1)CAS 61827-71-2
2-Amino-6-methoxybenzothiazoleCAS 1747-60-0
6-Ethyl-1,3-benzothiazol-2-amineCAS 21224-16-8
2-Aminobenzothiazole-6-carbonitrileCAS 19759-66-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 16582-58-46-Iodo-1,3-benzothiazol-2-amineCAS 61827-71-22-Benzothiazolamine, 6-chloro-, hydrochloride (1:1)CAS 1747-60-02-Amino-6-methoxybenzothiazoleCAS 21224-16-86-Ethyl-1,3-benzothiazol-2-amineCAS 19759-66-12-Aminobenzothiazole-6-carbonitrileCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 326-45-4

What are the key identifiers for 2-Amino-6-(trifluoromethylthio)benzothiazole (CAS 326-45-4)?

2-Amino-6-(trifluoromethylthio)benzothiazole is identified by CAS 326-45-4, with molecular formula C8H5F3N2S2, molecular weight 250.3, InChIKey PBRVVEXJMLEKMJ-UHFFFAOYSA-N.

Does CAS 326-45-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Pteridine reductase 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 326-45-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 2-Amino-6-(trifluoromethylthio)benzothiazole?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 326-45-4 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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