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Home/Compounds/CAS 326914-10-7
Formula C22H27ClN4O2MW 414.9Research-use catalog entryCOA/SDS by request

SU-11652

CAS Number: 326914-10-7

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Available options

Available Options

Package
10 mg
Purity
97%
Price
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Availability
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Loading RDKit molecule structure...
InChIKey: XPLJEFSRINKZLC-ATVHPVEESA-NC22H27ClN4O2 | MW 414.9

Chemical Absolute Identifiers

CAS Number

326914-10-7

PubChem CID

5329103

Molecular Formula

C22H27ClN4O2

Molecular Weight

414.9 g/mol

Exact Mass

414.182254

InChIKey

XPLJEFSRINKZLC-ATVHPVEESA-N

IUPAC Name

5-[(Z)-(5-chloro-2-oxo-1H-indol-3-ylidene)methyl]-N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide

SMILES String

CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(Cl)cc32)c1C

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

SU-11652 (CAS 326914-10-7) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C22H27ClN4O2 and molecular weight 414. 90 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Platelet-derived growth factor receptor beta (Homo sapiens) — 4 assays; Mast/stem cell growth factor receptor Kit (Homo sapiens) — 3 assays; Vascular endothelial growth factor receptor 2 (Homo sapiens) — 5 assays; Fibroblast growth factor receptor 1 (Homo sapiens) — 4 assays; Maternal embryonic leucine zipper kinase (Homo sapiens) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Platelet-derived growth factor receptor beta

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 8.52

Experimental evidence source: ChEMBL

Mast/stem cell growth factor receptor Kit

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 2 documents · best pChEMBL 8

Experimental evidence source: ChEMBL

Vascular endothelial growth factor receptor 2

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 4 documents · best pChEMBL 7.57

Experimental evidence source: ChEMBL

Fibroblast growth factor receptor 1

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 6.77

Experimental evidence source: ChEMBL

Maternal embryonic leucine zipper kinase

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 6.12

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

SU-11652

Names & Synonyms

5-((Z)-(5-Chloro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-N-(2-(diethylamino)ethyl)-2,4-dimethyl-1H-pyrrole-3-carboxamideSU 116521H-Pyrrole-3-carboxamide, 5-((Z)-(5-chloro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-N-(2-(diethylamino)ethyl)-2,4-dimethyl-5-[(Z)-(5-chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide5-{[(3Z)-5-chloro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
Show all synonyms
C22H27ClN4O2(Z)-5-((5-chloro-2-oxoindolin-3-ylidene)methyl)-N-(2-(diethylamino)ethyl)-2,4-dimethyl-1H-pyrrole-3-carboxamideSDCCGSBI-0086711.P0045-[(Z)-(5-chloro-1, 2-dihydro-2-oxo-3H-indol-3- ylidene)methyl]-N-[2-(diethylamino)ethyl]-2, 4-dimethyl-1H-pyrrole-3-carboxamide5-[(Z)-(5-chloro-2-oxo-indolin-3-ylidene)methyl]-N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID90648016CHEMBL ID: CHEMBL13485CHEBI ID: CHEBI:132084UNII: 1C7AZL970UDRUGBANK ID: DB08009METABOLOMICS WORKBENCH ID: 151158WIKIDATA ID: Q27088889
Literature & Patent References
DOI 10.1016/j.bmc.2017.03.018Discovery of a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth.PMID 28351607Discovery of a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth.DOI 10.1042/bj20121418A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.PMID 23398362A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.DOI 10.1073/pnas.0611681104c-Src protein kinase inhibitors block assembly and maturation of dengue virus.DOI 10.1073/pnas.0708800104A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.DOI 10.1074/jbc.m609721200Structure and regulation of the human Nek2 centrosomal kinase.PMID 17197699Structure and regulation of the human Nek2 centrosomal kinase.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Aq-13CAS 169815-40-1
LumefantrineCAS 82186-77-4
NiclosamideCAS 50-65-7
SpirodiclofenCAS 148477-71-8

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 120685-11-2MidostaurinCAS 189232-42-6BohemineCAS 62996-74-1StaurosporineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 326914-10-7

What are the key identifiers for SU-11652 (CAS 326914-10-7)?

SU-11652 is identified by CAS 326914-10-7, with molecular formula C22H27ClN4O2, molecular weight 414.9, InChIKey XPLJEFSRINKZLC-ATVHPVEESA-N.

Does CAS 326914-10-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Platelet-derived growth factor receptor beta, Mast/stem cell growth factor receptor Kit, Vascular endothelial growth factor receptor 2, Fibroblast growth factor receptor 1, Maternal embryonic leucine zipper kinase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 326914-10-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for SU-11652?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 326914-10-7 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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