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Home/Compounds/CAS 3457-48-5
Formula C16H14O2MW 238.28Research-use catalog entryCOA/SDS by request

1,2-Bis(4-methylphenyl)-1,2-ethanedione

CAS Number: 3457-48-5

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Loading RDKit molecule structure...
InChIKey: BCWCEHMHCDCJAD-UHFFFAOYSA-NC16H14O2 | MW 238.28

Chemical Absolute Identifiers

CAS Number

3457-48-5

PubChem CID

76996

Molecular Formula

C16H14O2

Molecular Weight

238.28 g/mol

Exact Mass

238.09938

InChIKey

BCWCEHMHCDCJAD-UHFFFAOYSA-N

IUPAC Name

1,2-bis(4-methylphenyl)ethane-1,2-dione

SMILES String

CC1=CC=C(C=C1)C(=O)C(=O)C2=CC=C(C=C2)C

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

1,2-Bis(4-methylphenyl)-1,2-ethanedione (CAS 3457-48-5) is listed in the Materials Science portfolio, with molecular formula C16H14O2 and molecular weight 238. 28 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for materials chemistry research and formulation screening workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Materials SciencePolymer ScienceResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Liver carboxylesterase 1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Liver carboxylesterase 1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.27

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide.

Disposal

  • The product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
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Fire Fighting

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Accidental Release

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For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

1,2-Bis(4-methylphenyl)-1,2-ethanedione

Names & Synonyms

4,4'-Dimethylbenzil1,2-Di-p-tolylethane-1,2-dioneDi-p-tolylethanedionebis(4-methylphenyl)ethane-1,2-dioneEthanedione, bis(4-methylphenyl)-
Show all synonyms
P,p'-dimethylbenzilEthandione, bis(p-tolyl)-4,4 inverted exclamation mark -Dimethylbenzilp-Tolil1,2-ethanedione, 1,2-bis(4-methylphenyl)-1,2-Di-p-tolyl-ethane-1,2-dione4,4//'-DimethylbenzilBenzil-based compound, 181,2-dip-tolylethane-1,2-dione1,2-bis(p-tolyl)ethane-1,2-dione1,2-bis(p-tolyl)-ethane-1,2-dione1,2-Di(4-methylphenyl)-1,2-ethanedione1,2-Bis(4-methylphenyl)-1,2-ethanedione #(E)-1,2-Bis(4-methylphenyl)ethane-1,2-dione
External Identifiers
EC NUMBER: 222-388-2DSSTOX SUBSTANCE ID: DTXSID60188116CHEMBL ID: CHEMBL192625UNII: 4HZ2Y7K8GZWIKIDATA ID: Q72469397
Experimental Spectrum References
13C NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR Spectra — Bio-Rad Laboratories, Inc.FTIR SpectraRaman Spectra — Bio-Rad LaboratoriesUV-VIS SpectraVapor Phase IR Spectra
Literature & Patent References
DOI 10.1016/j.bmc.2008.11.008Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis.PMID 19062296Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis.DOI 10.1021/jm049011jIdentification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.PMID 15828829Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.DOI 10.6019/CHEMBL3301361Experimental in vitro DMPK and physicochemical data on a set of publicly disclosed compounds

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

4,4'-DimethoxybenzilCAS 1226-42-2
Methanone, (4-((4-methylphenyl)thio)phenyl)phenyl-CAS 83846-85-9
4'-HydroxyacetophenoneCAS 99-93-4
1,4-DibenzoylbenzeneCAS 3016-97-5
4,4'-DichlorobenzophenoneCAS 90-98-2

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1226-42-24,4'-DimethoxybenzilCAS 83846-85-9Methanone, (4-((4-methylphenyl)thio)phenyl)phenyl-CAS 134-81-6BenzilCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 3457-48-5

What are the key identifiers for 1,2-Bis(4-methylphenyl)-1,2-ethanedione (CAS 3457-48-5)?

1,2-Bis(4-methylphenyl)-1,2-ethanedione is identified by CAS 3457-48-5, with molecular formula C16H14O2, molecular weight 238.28, InChIKey BCWCEHMHCDCJAD-UHFFFAOYSA-N.

Does CAS 3457-48-5 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Liver carboxylesterase 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 3457-48-5?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 1,2-Bis(4-methylphenyl)-1,2-ethanedione?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 3457-48-5 available for quotation?

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