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Home/Compounds/CAS 365-07-1
Formula C10H15N2O8PMW 322.21Research-use catalog entryCOA/SDS by request

5'-Thymidylic acid

CAS Number: 365-07-1

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Loading RDKit molecule structure...
InChIKey: GYOZYWVXFNDGLU-XLPZGREQSA-NC10H15N2O8P | MW 322.21

Chemical Absolute Identifiers

CAS Number

365-07-1

PubChem CID

9700

Molecular Formula

C10H15N2O8P

Molecular Weight

322.21 g/mol

Exact Mass

322.056602

InChIKey

GYOZYWVXFNDGLU-XLPZGREQSA-N

IUPAC Name

[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate

SMILES String

CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=O)(O)O)O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

5'-Thymidylic acid (CAS 365-07-1) is listed in the Life Science portfolio, with molecular formula C10H15N2O8P and molecular weight 322. 21 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for life-science research and analytical workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Life Science ResearchNucleic Acid ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Thymidylate kinase (Mycobacterium tuberculosis) — 11 assays; Thymidylate synthase (Lactobacillus casei) — 2 assays; Thymidylate kinase (Homo sapiens) — 5 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Thymidylate kinase

Mycobacterium tuberculosis · SINGLE PROTEIN · 11 qualifying assays · 8 documents · best pChEMBL 7.16

Experimental evidence source: ChEMBL

Thymidylate synthase

Lactobacillus casei · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.06

Experimental evidence source: ChEMBL

Thymidylate kinase

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 3 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.
  • Avoid contact with skin and eyes.

PPE

Respiratory protection if needed

First Aid

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  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, nitrogen oxides, phosphorus oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

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  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

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Names & Synonyms / External Identifiers

Chemical Name

5'-Thymidylic acid

Names & Synonyms

dTMPthymidine monophosphateThymidine 5'-monophosphate5-Methyl-dUMPThymidylate
Show all synonyms
Thymidine mononucleotideThymidine 5'-phosphateDeoxy TMPThymidine-5'-monophosphoric acidDeoxythymidine 5'-phosphateDeoxythymidine monophosphateDeoxyribosylthymine monophosphateThymidine 5'-phosphoric acidTMP (nucleotide)Deoxythymidylic acid5'-TMPthymidine-5'-monophosphateThymidine 5'-(dihydrogen phosphate)Thymidine, mono(dihydrogen phosphate) (ester)ribothymidine 5'-monophosphate
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID60904171CHEMBL ID: CHEMBL394429CHEBI ID: CHEBI:17013UNII: 43W3021X6CDRUGBANK ID: DB01643HMDB ID: HMDB0001227KEGG ID: C00364METABOLOMICS WORKBENCH ID: 37671METABOLOMICS WORKBENCH ID: 62844PHARMGKB ID: PA166178644WIKIDATA ID: Q23905769
Experimental Spectrum References
13C NMR Spectra1H NMR Spectra31P NMR Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2023.115409Comprehensive coverage on anti-mycobacterial endeavour reported during 2022.PMID 37120997Comprehensive coverage on anti-mycobacterial endeavour reported during 2022.DOI 10.1021/acs.jnatprod.0c00719S-Bridged Thioether and Structure-Diversified Angucyclinone Derivatives from the South China Sea-Derived Micromonospora echinospora SCSIO 04089.PMID 32970433S-Bridged Thioether and Structure-Diversified Angucyclinone Derivatives from the South China Sea-Derived Micromonospora echinospora SCSIO 04089.DOI 10.1016/j.ejmech.2015.01.035Synthesis, molecular docking and Brugia malayi thymidylate kinase (BmTMK) enzyme inhibition study of novel derivatives of [6]-shogaol.PMID 25659753Synthesis, molecular docking and Brugia malayi thymidylate kinase (BmTMK) enzyme inhibition study of novel derivatives of [6]-shogaol.DOI 10.1021/jm1011462Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates.PMID 21128666Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

5'-O-tert-ButyldimethylsilylthymidineCAS 40733-28-6
1-(2-Deoxy-5-O-(triphenylmethyl)pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dioneCAS 7791-71-1
5-Methyl dCMPCAS 2498-41-1
3'-AminothymidineCAS 52450-18-7
Deoxy-4-thiothymidineCAS 7236-57-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 40733-28-65'-O-tert-ButyldimethylsilylthymidineCAS 7791-71-11-(2-Deoxy-5-O-(triphenylmethyl)pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dioneCAS 2498-41-15-Methyl dCMPCAS 52450-18-73'-AminothymidineCAS 7236-57-9Deoxy-4-thiothymidineCAS 30516-87-1ZidovudineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 365-07-1

What are the key identifiers for 5'-Thymidylic acid (CAS 365-07-1)?

5'-Thymidylic acid is identified by CAS 365-07-1, with molecular formula C10H15N2O8P, molecular weight 322.21, InChIKey GYOZYWVXFNDGLU-XLPZGREQSA-N.

Does CAS 365-07-1 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Thymidylate kinase, Thymidylate synthase, Thymidylate kinase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 365-07-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 5'-Thymidylic acid?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 365-07-1 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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