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Home/Compounds/CAS 372196-67-3
Formula C16H14BrN5O4SMW 452.3Research-use catalog entryCOA/SDS by request

Pik-75

CAS Number: 372196-67-3

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Loading RDKit molecule structure...
InChIKey: QTHCAAFKVUWAFI-DJKKODMXSA-NC16H14BrN5O4S | MW 452.3

Chemical Absolute Identifiers

CAS Number

372196-67-3

PubChem CID

10275789

Molecular Formula

C16H14BrN5O4S

Molecular Weight

452.3 g/mol

Exact Mass

450.99499

InChIKey

QTHCAAFKVUWAFI-DJKKODMXSA-N

IUPAC Name

N-[(E)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylideneamino]-N,2-dimethyl-5-nitrobenzenesulfonamide

SMILES String

Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)/N=C/c1cnc2ccc(Br)cn12

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Pik-75 (CAS 372196-67-3) is listed in the Advanced Chemicals portfolio, with molecular formula C16H14BrN5O4S and molecular weight 452. 30 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Organic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Dual specificity protein kinase CLK1 (Homo sapiens) — 4 assays; Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens) — 4 assays; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens) — 4 assays; Cyclin-dependent kinase 9 (Homo sapiens) — 3 assays; Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Dual specificity protein kinase CLK1

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents · best pChEMBL 10.25

Experimental evidence source: ChEMBL

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents · best pChEMBL 10.05

Experimental evidence source: ChEMBL

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 4 documents · best pChEMBL 9.3

Experimental evidence source: ChEMBL

Cyclin-dependent kinase 9

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 2 documents · best pChEMBL 8.85

Experimental evidence source: ChEMBL

Dual specificity tyrosine-phosphorylation-regulated kinase 1B

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 8.47

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Pik-75

Names & Synonyms

PIK 75Benzenesulfonic acid, 2-methyl-5-nitro-, 2-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-1-methylhydrazideN-((E)-(6-bromoimidazo(1,2-a)pyridin-3-yl)methylideneamino)-N,2-dimethyl-5-nitrobenzenesulfonamidePIK75(E)-N'-((6-bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazide
Show all synonyms
2-Methyl-5-nitro-1-benzenesulfonic acid 2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazidePIK 75 hydrochlorideC16H14BrN5O4SPIK-75 (hydrochloride)N'-((6-bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazidePIK-75 free base?PIK-75, free baseimidazopyridine derivative 8c [PMID 17601739]imidazopyridine derivative, 8cN-[(z)-(6-Bromoimidazo[1,2-a]pyridin-3-yl)methylideneamino]-N,2-dimethyl-5-nitrobenzenesulfonamidePIK-75, 1SDCCGSBI-0207186.P005N''-[(1E)-{6-bromoimidazo[1,2-a]pyridin-3-yl}methylidene]-N,2-dimethyl-5-nitrobenzene-1-sulfonohydrazideN'-((6-Bromoimidazo[1,2,a]Pyridin-3-Yl)Methylene)-N,2-Dimethyl-5-Nitrobenzenesulfonohydrazide
External Identifiers
CHEMBL ID: CHEMBL393525CHEBI ID: CHEBI:94827UNII: 9058I8S63DDRUGBANK ID: DB17047
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c00312Recent Discovery and Development of Inhibitors that Target CDK9 and Their Therapeutic Indications.PMID 38564299Recent Discovery and Development of Inhibitors that Target CDK9 and Their Therapeutic Indications.DOI 10.1016/j.bmc.2023.117406Glycogen synthase kinase-3: A potential target for diabetes.DOI 10.1021/acs.jmedchem.2c02068Comparative Efficacy and Selectivity of Pharmacological Inhibitors of DYRK and CLK Protein Kinases.PMID 36876904Comparative Efficacy and Selectivity of Pharmacological Inhibitors of DYRK and CLK Protein Kinases.PMID 37536264Glycogen synthase kinase-3: A potential target for diabetes.DOI 10.1021/acs.jmedchem.0c01467Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.PMID 33539089Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

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RFQ questions for CAS 372196-67-3

What are the key identifiers for Pik-75 (CAS 372196-67-3)?

Pik-75 is identified by CAS 372196-67-3, with molecular formula C16H14BrN5O4S, molecular weight 452.3, InChIKey QTHCAAFKVUWAFI-DJKKODMXSA-N.

Does CAS 372196-67-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Dual specificity protein kinase CLK1, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Cyclin-dependent kinase 9, Dual specificity tyrosine-phosphorylation-regulated kinase 1B. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 372196-67-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Pik-75?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 372196-67-3 available for quotation?

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