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Home/Compounds/CAS 3736-81-0
Formula C14H11Cl2NO4MW 328.1Research-use catalog entryCOA/SDS by request

Diloxanide furoate

CAS Number: 3736-81-0

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Loading RDKit molecule structure...
InChIKey: BDYYDXJSHYEDGB-UHFFFAOYSA-NC14H11Cl2NO4 | MW 328.1

Chemical Absolute Identifiers

CAS Number

3736-81-0

PubChem CID

19529

Molecular Formula

C14H11Cl2NO4

Molecular Weight

328.1 g/mol

Exact Mass

327.006513

InChIKey

BDYYDXJSHYEDGB-UHFFFAOYSA-N

IUPAC Name

[4-[(2,2-dichloroacetyl)-methylamino]phenyl] furan-2-carboxylate

SMILES String

CN(C1=CC=C(C=C1)OC(=O)C2=CC=CO2)C(=O)C(Cl)Cl

Physical Properties

Water Solubility

49.2 mol/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Diloxanide furoate (CAS 3736-81-0) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C14H11Cl2NO4 and molecular weight 328. 10 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Hypoxia-inducible factor 1-alpha (Homo sapiens) — 2 assays; Cytochrome P450 3A4 (Homo sapiens) — 2 assays; Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Hypoxia-inducible factor 1-alpha

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.6

Experimental evidence source: ChEMBL

Cytochrome P450 3A4

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.8

Experimental evidence source: ChEMBL

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity.
  • Carbon monoxide, carbon dioxide, hydrogen chloride, nitrogen oxides.

Disposal

  • Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Diloxanide furoate

Names & Synonyms

DichlofurazolFurentominAmebiazolHistomibalEntamide furoate
Show all synonyms
Diloxanid furoateDiclofurazolMiforon8073 CBDiloxanidi furoasDiloxanide furoate (USP)Diloxanide furoate [USP]CB 80732,2-dichloroacetamido-4-n-methylphenyl 2-furoate4-(n-methyl-2,2-dichloroacetamido)phenyl 2-furoate2,2-dichloro-4'-hydroxy-N-methylacetanilide 2-furoate2-Furoic acid, ester with 2,2-dichloro-4'-hydroxy-N-methylacetanilide2-Furancarboxylic acid, 4-[(dichloroacetyl)methylamino]phenyl ester2-Furancarboxylic acid, 4-((dichloroacetyl)methylamino)phenyl ester
External Identifiers
EC NUMBER: 223-108-1DSSTOX SUBSTANCE ID: DTXSID8048999CHEMBL ID: CHEMBL1334860CHEBI ID: CHEBI:4601UNII: YP4N72IW34DRUGBANK ID: DB14638HMDB ID: HMDB0015684KEGG ID: C07637KEGG ID: D02480NCI THESAURUS CODE: C217852WIKIDATA ID: Q799564
Experimental Spectrum References
13C NMR Spectra
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.1101/2020.04.03.023846In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replicationDOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effort

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 131-53-32,2'-Dihydroxy-4-methoxybenzophenoneCAS 13710-19-5Tolfenamic AcidCAS 142720-24-92-(4-Fluorophenyl)-N,N-dihexyl-1H-indole-3-acetamideCAS 100643-71-8DesloratadineCAS 101831-37-2DiclazurilCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 3736-81-0

What are the key identifiers for Diloxanide furoate (CAS 3736-81-0)?

Diloxanide furoate is identified by CAS 3736-81-0, with molecular formula C14H11Cl2NO4, molecular weight 328.1, InChIKey BDYYDXJSHYEDGB-UHFFFAOYSA-N.

Does CAS 3736-81-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Hypoxia-inducible factor 1-alpha, Cytochrome P450 3A4, Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 3736-81-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Diloxanide furoate?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 3736-81-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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