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Home/Compounds/CAS 38821-53-3
Formula C16H19N3O4SMW 349.4Research-use catalog entryCOA/SDS by request

Cephradine

CAS Number: 38821-53-3

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Loading RDKit molecule structure...
InChIKey: RDLPVSKMFDYCOR-UEKVPHQBSA-NC16H19N3O4S | MW 349.4

Chemical Absolute Identifiers

CAS Number

38821-53-3

PubChem CID

38103

Molecular Formula

C16H19N3O4S

Molecular Weight

349.4 g/mol

Exact Mass

349.109627

InChIKey

RDLPVSKMFDYCOR-UEKVPHQBSA-N

IUPAC Name

(6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

SMILES String

CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CCC=CC3)N)SC1)C(=O)O

Physical Properties

Melting Point

14.0 °C

pKa

1

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Cephradine (CAS 38821-53-3) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C16H19N3O4S and molecular weight 349. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Nuclear receptor subfamily 1 group I member 2 (Homo sapiens) — 3 assays; Progesterone receptor (Homo sapiens) — 2 assays; Solute carrier family 15 member 2 (Rattus norvegicus) — 2 assays; 5-hydroxytryptamine receptor 2A (Homo sapiens) — 2 assays; 5-hydroxytryptamine receptor 2B (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Nuclear receptor subfamily 1 group I member 2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 4.66

Experimental evidence source: ChEMBL

Progesterone receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.66

Experimental evidence source: ChEMBL

Solute carrier family 15 member 2

Rattus norvegicus · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 4.33

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2A

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2B

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

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  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction stability.
  • Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides.

Disposal

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  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

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Accidental Release

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  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

Cephradine

Names & Synonyms

CefradineCephradinAnsporSefrilVelosef
Show all synonyms
CefradinaEskacefCefradinumSQ 11436Cephradine anhydrous(6R,7R)-7-((R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid7-(D-2-Amino-2-(1,4-cyclohexadienyl)acetamide)desacetoxycephalosporanicacidCephradine hydrateCEFRADINE HYDRATESK&F D-39304(6R,7R)-7-[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid7-(D-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)-oct-2-ene-2-caboxylic acidSK&F-D-39304(6R,7R)-7-{[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
External Identifiers
EC NUMBER: 254-137-8DSSTOX SUBSTANCE ID: DTXSID4022785CHEMBL ID: CHEMBL1604CHEBI ID: CHEBI:3547UNII: 9YA6SX5S4DDRUGBANK ID: DB01333HMDB ID: HMDB0015428KEGG ID: C06897KEGG ID: D00264METABOLOMICS WORKBENCH ID: 43501NCI THESAURUS CODE: C47441NCI THESAURUS CODE: C76181PHARMGKB ID: PA448890
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effort

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Cephalexin MonohydrateCAS 23325-78-2
CefadroxilCAS 50370-12-2
CefaclorCAS 53994-73-3
Cefprozil MonohydrateCAS 121123-17-9
CefuroximeCAS 55268-75-2

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 23325-78-2Cephalexin MonohydrateCAS 50370-12-2CefadroxilCAS 53994-73-3CefaclorCAS 121123-17-9Cefprozil MonohydrateCAS 102767-28-2LevetiracetamCAS 106308-44-5RufinamideCAS 107724-20-9EplerenoneCAS 1617-90-9VincamineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acid

RFQ questions for CAS 38821-53-3

What are the key identifiers for Cephradine (CAS 38821-53-3)?

Cephradine is identified by CAS 38821-53-3, with molecular formula C16H19N3O4S, molecular weight 349.4, InChIKey RDLPVSKMFDYCOR-UEKVPHQBSA-N.

Does CAS 38821-53-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Nuclear receptor subfamily 1 group I member 2, Progesterone receptor, Solute carrier family 15 member 2, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 38821-53-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Cephradine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 38821-53-3 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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