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Home/Compounds/CAS 4005-51-0
Formula C2H3N3SMW 101.13Research-use catalog entryCOA/SDS by request

1,3,4-Thiadiazol-2-amine

CAS Number: 4005-51-0

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Loading RDKit molecule structure...
InChIKey: QUKGLNCXGVWCJX-UHFFFAOYSA-NC2H3N3S | MW 101.13

Chemical Absolute Identifiers

CAS Number

4005-51-0

PubChem CID

19909

Molecular Formula

C2H3N3S

Molecular Weight

101.13 g/mol

Exact Mass

101.004768

InChIKey

QUKGLNCXGVWCJX-UHFFFAOYSA-N

SMILES String

C1=NN=C(S1)N

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

1,3,4-Thiadiazol-2-amine (CAS 4005-51-0) is listed in the Advanced Chemicals portfolio, with molecular formula C2H3N3S and molecular weight 101. 13 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.
  • Avoid contact with skin and eyes.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything by mouth to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
Show additional safety reference fields

Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

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  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

1,3,4-Thiadiazol-2-amine

Names & Synonyms

2-Amino-1,3,4-thiadiazoleAminothiadiazole2-AminothiadiazoleFDA 00841,3,4-Thiadiazole, 2-amino
Show all synonyms
2-Amino-1-thia-3,4-diazoleAmino 134-Thiadiazole1,3, 4-Thiadiazol-2-amine1,3, 4-Thiadiazole, 2-amino-ATDATF 128X 261,3,4-thiadiazol-2-ylamine1,3,4-THIADIAZOLE, 2-AMINO-[1,3,4]Thiadiazol-2-ylamine1,3,4-Thiadiazole-2-Amine1,3,4-Thiadiazole-2-ylamine1,4-Thiadiazol-2-amine2-Amino-1,4-thiadiazoleNCIMech_000679
External Identifiers
EC NUMBER: 223-657-7DSSTOX SUBSTANCE ID: DTXSID50193113CHEMBL ID: CHEMBL1650237UNII: 6L41AOK74PHMDB ID: HMDB0244972NCI THESAURUS CODE: C1335WIKIDATA ID: Q27265082
Experimental Spectrum References
13C NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR Spectra — Bio-Rad Laboratories, Inc.FTIR SpectraRaman Spectra — Bio-Rad Laboratories, Inc.UV-VIS Spectra
Literature & Patent References
DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortDOI 10.1007/s00044-012-0336-zSynthesis, antioxidant, and antitumor evaluation of certain new N-substituted-2-amino-1,3,4-thiadiazolesDOI 10.1021/jm4001488Synthesis and mechanism of hypoglycemic activity of benzothiazole derivatives.PMID 23750537Synthesis and mechanism of hypoglycemic activity of benzothiazole derivatives.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

2-Chloro-1,3,4-thiadiazoleCAS 52819-57-5
N-methyl-1,3,4-thiadiazol-2-amineCAS 38490-45-8
1,3,4-Thiadiazole-2,5-diamineCAS 2937-81-7
2-Amino-5-bromo-1,3,4-thiadiazoleCAS 37566-39-5
1,3,4-Thiadiazole, 2-amino-5-methyl-CAS 108-33-8

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 52819-57-52-Chloro-1,3,4-thiadiazoleCAS 38490-45-8N-methyl-1,3,4-thiadiazol-2-amineCAS 79-19-6ThiosemicarbazideCAS 85916-84-31-methylimidazole-2-thiolCAS 100-88-9CyclamateCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 4005-51-0

What are the key identifiers for 1,3,4-Thiadiazol-2-amine (CAS 4005-51-0)?

1,3,4-Thiadiazol-2-amine is identified by CAS 4005-51-0, with molecular formula C2H3N3S, molecular weight 101.13, InChIKey QUKGLNCXGVWCJX-UHFFFAOYSA-N.

Does CAS 4005-51-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 4005-51-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 1,3,4-Thiadiazol-2-amine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 4005-51-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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