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Home/Compounds/CAS 4273-92-1
Formula C19H16ClNO4MW 357.8Research-use catalog entryCOA/SDS by request

2-Naphthalenecarboxamide, N-(4-chloro-2,5-dimethoxyphenyl)-3-hydroxy-

CAS Number: 4273-92-1

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Loading RDKit molecule structure...
InChIKey: QIHKTBRNOLQDGQ-UHFFFAOYSA-NC19H16ClNO4 | MW 357.8

Chemical Absolute Identifiers

CAS Number

4273-92-1

PubChem CID

77955

Molecular Formula

C19H16ClNO4

Molecular Weight

357.8 g/mol

Exact Mass

357.076786

InChIKey

QIHKTBRNOLQDGQ-UHFFFAOYSA-N

IUPAC Name

N-(4-chloro-2,5-dimethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide

SMILES String

COC1=CC(=C(C=C1NC(=O)C2=CC3=CC=CC=C3C=C2O)OC)Cl

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

2-Naphthalenecarboxamide, N-(4-chloro-2,5-dimethoxyphenyl)-3-hydroxy- (CAS 4273-92-1) is listed in the Materials Science portfolio, with molecular formula C19H16ClNO4 and molecular weight 357. 80 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for materials chemistry research and formulation screening workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Dyes and PigmentsMaterials ScienceResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Microtubule-associated protein tau (Homo sapiens) — 2 assays; Mothers against decapentaplegic homolog 3 (Homo sapiens) — 4 assays; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Homo sapiens) — 2 assays; Thyrotropin receptor (Homo sapiens) — 2 assays; Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Microtubule-associated protein tau

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.9

Experimental evidence source: ChEMBL

Mothers against decapentaplegic homolog 3

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Thyrotropin receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Tyrosyl-DNA phosphodiesterase 1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

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Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

2-Naphthalenecarboxamide, N-(4-chloro-2,5-dimethoxyphenyl)-3-hydroxy-

Names & Synonyms

N-(4-chloro-2,5-dimethoxyphenyl)-3-hydroxy-2-naphthalenecarboxamide4'-Chloro-3-hydroxy-2',5'-dimethoxy-2-naphthanilideN-(4-Chloro-2,5-dimethoxyphenyl)-3-hydroxy-2-naphthamideNaphthol AS-LCNaphtazol LC
Show all synonyms
Sanatol LCNaphtol AS-LCNaphtanilide LCNaphtol AS-LCLLC.I. Azoic Coupling Component 23C.I. 375552-Naphthanilide,5'-dimethoxy-2-Naphthalenecarboxamide,5-dimethoxyphenyl)-3-hydroxy-EC 224-270-6NCIOpen2_008694cid_779552-Naphthanilide, 4'-chloro-3-hydroxy-2',5'-dimethoxy-N-(4-chloro-2,5-dimethoxy-phenyl)-3-hydroxy-naphthalene-2-carboxamideN-(4-chloro-2,5-dimethoxy-phenyl)-3-hydroxy-2-naphthamide
External Identifiers
EC NUMBER: 224-270-6DSSTOX SUBSTANCE ID: DTXSID8063385CHEMBL ID: CHEMBL1456848UNII: 8KEU3457L4WIKIDATA ID: Q72493608
Experimental Spectrum References
13C NMR Spectra1H NMR SpectraFTIR SpectraUV-VIS Spectra
Literature & Patent References
DOI 10.1016/j.bmcl.2011.09.094Novel inhibitors of Mycobacterium tuberculosis dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD) identified by virtual screening.PMID 22014548Novel inhibitors of Mycobacterium tuberculosis dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD) identified by virtual screening.DOI 10.6019/CHEMBL4296182CO-ADD screening of NIH NCI Diversity Set V

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
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  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

4-Chloro-2,5-dimethoxyanilineCAS 6358-64-1
Acetamide, N-[3-[bis(2-hydroxyethyl)amino]-4-methoxyphenyl]-CAS 24530-67-4
N-(4-Hydroxymetanilyl)anthranilic acidCAS 91-35-0
7-Benzamido-4-hydroxynaphthalene-2-sulphonic acidCAS 132-87-6
2,4-Dihydroxy-N-(2-hydroxyethyl)benzamideCAS 24207-41-8

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 118-75-2ChloranilCAS 1239-45-8Ethidium BromideCAS 135276-47-01-(4-Fluorophenyl)-3-(2-hydroxyphenyl)propane-1,3-dioneCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 4273-92-1

What are the key identifiers for 2-Naphthalenecarboxamide, N-(4-chloro-2,5-dimethoxyphenyl)-3-hydroxy- (CAS 4273-92-1)?

2-Naphthalenecarboxamide, N-(4-chloro-2,5-dimethoxyphenyl)-3-hydroxy- is identified by CAS 4273-92-1, with molecular formula C19H16ClNO4, molecular weight 357.8, InChIKey QIHKTBRNOLQDGQ-UHFFFAOYSA-N.

Does CAS 4273-92-1 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Microtubule-associated protein tau, Mothers against decapentaplegic homolog 3, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Thyrotropin receptor, Tyrosyl-DNA phosphodiesterase 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 4273-92-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 2-Naphthalenecarboxamide, N-(4-chloro-2,5-dimethoxyphenyl)-3-hydroxy-?

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