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5-(1-Methylcyclopropyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid

CAS 436088-38-9Formula C12H10F3N3O2MW 285.22PubChem 3145956

5-(1-Methylcyclopropyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is a pyrazolopyrimidine derivative featuring a trifluoromethyl group and a carboxylic acid moiety, making it a valuable compound for research in medicinal chemistry and drug discovery.

Loading RDKit molecule structure...
InChIKey: UVQZUXPEYVUBAO-UHFFFAOYSA-NC12H10F3N3O2 | MW 285.22

Chemical Identity

Molecular Formula

C12H10F3N3O2

Molecular Weight

285.22 g/mol

Exact Mass

285.072511

PubChem CID

3145956

SMILES String

CC1(c2cc(C(F)(F)F)n3nc(C(=O)O)cc3n2)CC1

Names & Synonyms

5-(1-Methyl-cyclopropyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-2-carboxylic acidHMS2471O18BAS 03183145Pyrazolo[1,5-a]pyrimidine-2-carboxylicacid, 5-(1-methylcyclopropyl)-7-(trifluoromethyl)-
External Identifiers
SMR000124866MLS000067414CHEMBL1598221DTXSID80389820AKOS000557005SR-01000325102SR-01000325102-1

Catalog Overview

5-(1-Methylcyclopropyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, identified by CAS 436088-38-9, is an organic compound with the molecular formula C12H10F3N3O2 and a molecular weight of 285. 22 g/mol. This compound belongs to the pyrazolopyrimidine class, characterized by a fused bicyclic ring system. It incorporates a 1-methylcyclopropyl substituent at the 5-position, a trifluoromethyl group at the 7-position, and a carboxylic acid group at the 2-position.

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

5-(1-Methylcyclopropyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, identified by CAS 436088-38-9, is an organic compound with the molecular formula C12H10F3N3O2 and a molecular weight of 285.22 g/mol. This compound belongs to the pyrazolopyrimidine class, characterized by a fused bicyclic ring system. It incorporates a 1-methylcyclopropyl substituent at the 5-position, a trifluoromethyl group at the 7-position, and a carboxylic acid group at the 2-position. Its 'druglike_bioactive_like' structural bucket suggests its potential utility as a scaffold or building block in the synthesis of novel chemical entities for pharmaceutical research and development.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White solid

Physical State

Solid

Melting Point

165.0 °C

Boiling Point

308.0 °C

Density

1.4 g/cm³

Water Solubility

Slightly soluble

Flash Point

220.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle 5-(1-Methylcyclopropyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse thoroughly with water. Store in a cool, dry place, away from incompatible materials. Always refer to the Safety Data Sheet (SDS) for comprehensive safety information before handling.

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