- Package
- 10 mg
- Purity
- 98%
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CAS Number: 4449-51-8
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CAS Number
4449-51-8
PubChem CID
442972
Molecular Formula
C27H41NO2
Molecular Weight
411.6 g/mol
Exact Mass
411.31373
InChIKey
QASFUMOKHFSJGL-LAFRSMQTSA-N
IUPAC Name
(3S,3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-3',6',10,11b-tetramethylspiro[2,3,4,6,6a,6b,7,8,11,11a-decahydro-1H-benzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-3-ol
SMILES String
C[C@H]1C[C@@H]2[C@H]([C@H]([C@]3(O2)CC[C@H]4[C@@H]5CC=C6C[C@H](CC[C@@]6([C@H]5CC4=C3C)C)O)C)NC1
No physical property values available.
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Cyclopamine (CAS 4449-51-8) is listed in the Advanced Chemicals portfolio, with molecular formula C27H41NO2 and molecular weight 411. 60 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: Protein smoothened (Homo sapiens) — 10 assays; Sonic hedgehog protein (Mus musculus) — 9 assays; Protein smoothened (Mus musculus) — 4 assays; Sigma intracellular receptor 2 (Homo sapiens) — 2 assays; Alpha-2A adrenergic receptor (Homo sapiens) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Protein smoothened
Homo sapiens · SINGLE PROTEIN · 10 qualifying assays · 4 documents · best pChEMBL 7.91
Experimental evidence source: ChEMBL
Sonic hedgehog protein
Mus musculus · SINGLE PROTEIN · 9 qualifying assays · 3 documents · best pChEMBL 6.52
Experimental evidence source: ChEMBL
Protein smoothened
Mus musculus · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 6.32
Experimental evidence source: ChEMBL
Sigma intracellular receptor 2
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.22
Experimental evidence source: ChEMBL
Alpha-2A adrenergic receptor
Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 2 documents
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.
Preliminary Safety Reference
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Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Cyclopamine is identified by CAS 4449-51-8, with molecular formula C27H41NO2, molecular weight 411.6, InChIKey QASFUMOKHFSJGL-LAFRSMQTSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Protein smoothened, Sonic hedgehog protein, Protein smoothened, Sigma intracellular receptor 2, Alpha-2A adrenergic receptor. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
Availability, pack size, lead time, and pricing are confirmed through RFQ.
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