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Home/Compounds/CAS 455-24-3
Formula C8H5F3O2MW 190.12Research-use catalog entryCOA/SDS by request

4-(Trifluoromethyl)benzoic acid

CAS Number: 455-24-3

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Available Options

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1 g
Purity
97%
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Loading RDKit molecule structure...
InChIKey: SWKPKONEIZGROQ-UHFFFAOYSA-NC8H5F3O2 | MW 190.12

Chemical Absolute Identifiers

CAS Number

455-24-3

PubChem CID

9966

Molecular Formula

C8H5F3O2

Molecular Weight

190.12 g/mol

Exact Mass

190.024164

InChIKey

SWKPKONEIZGROQ-UHFFFAOYSA-N

SMILES String

C1=CC(=CC=C1C(=O)O)C(F)(F)F

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

4-(Trifluoromethyl)benzoic acid (CAS 455-24-3) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C8H5F3O2 and molecular weight 190. 12 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity.
  • Carbon monoxide, carbon dioxide, hydrogen fluoride.

Disposal

  • Dispose of the product by handing over the remaining and non-recyclable solution to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Use personal protective equipment and emergency procedures.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

4-(Trifluoromethyl)benzoic acid

Names & Synonyms

4-TRIFLUOROMETHYLBENZOIC ACIDp-Trifluoromethylbenzoic acidBenzoic acid, 4-(trifluoromethyl)-4-trifluoromethyl benzoic acidPara-(trifluoromethyl)benzoic acid
Show all synonyms
alpha,alpha,alpha-Trifluoro-p-toluic acidP-CARBOXYBENZOTRIFLUORIDEp-trifluoroformylbenzoic acid4-Trifluoromethyl-benzoic acid.alpha.,.alpha.,.alpha.-trifluoro-p-toluic acid4-(Trifluoromethyl)benzoicAcid3AETFMBAEnamine_005626NCIOpen2_001327paratrifluoromethylbenzoic acidTECOVIRIMAT METABOLITE (TFMBA)AO-801/41077414InChI=1/C8H5F3O2/c9-8(10,11)6-3-1-5(2-4-6)7(12)13/h1-4H,(H,12,13
External Identifiers
EC NUMBER: 207-242-8DSSTOX SUBSTANCE ID: DTXSID0060018CHEMBL ID: CHEMBL443234CHEBI ID: CHEBI:60696UNII: KA05X8S21ZHMDB ID: HMDB0246315METABOLOMICS WORKBENCH ID: 61230WIKIDATA ID: Q27128434Fr12653
Experimental Spectrum References
13C NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR SpectraRaman Spectra — Bio-Rad Laboratories, Inc.Vapor Phase IR Spectra
Literature & Patent References
DOI 10.1021/acs.jmedchem.0c00407Phosphine Oxides from a Medicinal Chemist's Perspective: Physicochemical and in Vitro Parameters Relevant for Drug Discovery.PMID 32479078Phosphine Oxides from a Medicinal Chemist's Perspective: Physicochemical and in Vitro Parameters Relevant for Drug Discovery.DOI 10.1021/jm950589qComparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.PMID 8667357Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.DOI 10.1021/jm00072a012QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods.PMID 8411009QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods.DOI 10.1021/jm00096a014Energy aspects of oil/water partition leading to the novel hydrophobic parameters for the analysis of quantitative structure-activity relationships.PMID 1527790Energy aspects of oil/water partition leading to the novel hydrophobic parameters for the analysis of quantitative structure-activity relationships.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

4-(Trifluoromethyl)anilineCAS 455-14-1
3-oxo-N-(4-(trifluoromethyl)phenyl)butanamideCAS 351-87-1
2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamideCAS 24522-30-3
TeriflunomideCAS 163451-81-8
LeflunomideCAS 75706-12-6

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 455-14-14-(Trifluoromethyl)anilineCAS 351-87-13-oxo-N-(4-(trifluoromethyl)phenyl)butanamideCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 455-24-3

What are the key identifiers for 4-(Trifluoromethyl)benzoic acid (CAS 455-24-3)?

4-(Trifluoromethyl)benzoic acid is identified by CAS 455-24-3, with molecular formula C8H5F3O2, molecular weight 190.12, InChIKey SWKPKONEIZGROQ-UHFFFAOYSA-N.

Can I request a COA for CAS 455-24-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 4-(Trifluoromethyl)benzoic acid?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 455-24-3 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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