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Home/Compounds/CAS 481-39-0
Formula C10H6O3MW 174.15Research-use catalog entryCOA/SDS by request

Juglone

CAS Number: 481-39-0

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Loading RDKit molecule structure...
InChIKey: KQPYUDDGWXQXHS-UHFFFAOYSA-NC10H6O3 | MW 174.15

Chemical Absolute Identifiers

CAS Number

481-39-0

PubChem CID

3806

Molecular Formula

C10H6O3

Molecular Weight

174.15 g/mol

Exact Mass

174.031694

InChIKey

KQPYUDDGWXQXHS-UHFFFAOYSA-N

IUPAC Name

5-hydroxynaphthalene-1,4-dione

SMILES String

C1=CC2=C(C(=O)C=CC2=O)C(=C1)O

Physical Properties

Melting Point

155.0 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Juglone (CAS 481-39-0) is listed in the Life Science portfolio, with molecular formula C10H6O3 and molecular weight 174. 15 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for life-science research and analytical workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Life Science ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens) — 3 assays; Protein disulfide-isomerase (Homo sapiens) — 2 assays; ATP-dependent DNA helicase Q1 (Homo sapiens) — 2 assays; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Homo sapiens) — 11 assays; Microtubule-associated protein tau (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Tyrosyl-DNA phosphodiesterase 1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 6.45

Experimental evidence source: ChEMBL

Protein disulfide-isomerase

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.2

Experimental evidence source: ChEMBL

ATP-dependent DNA helicase Q1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.75

Experimental evidence source: ChEMBL

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

Homo sapiens · SINGLE PROTEIN · 11 qualifying assays · 8 documents · best pChEMBL 5.3

Experimental evidence source: ChEMBL

Microtubule-associated protein tau

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 5.15

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Juglone

Names & Synonyms

5-Hydroxy-1,4-naphthalenedione5-Hydroxy-1,4-naphthoquinoneRegianinNucin8-Hydroxy-1,4-naphthoquinone
Show all synonyms
C.I. Natural Brown 7C.I. 75500JuglonAkhnotYuglon5-Hydroxynaphthoquinone1,4-NAPHTHALENEDIONE, 5-HYDROXY-5-Hydroxy-p-naphthoquinone1,4-Naphthoquinone, 5-hydroxy-JuglaneJugnlonIuglon1,4-Naphthoquinone, 8-hydroxy-5-Hydroxy-1,4-naphthosemiquinone
External Identifiers
EC NUMBER: 207-567-5DSSTOX SUBSTANCE ID: DTXSID0031504CHEMBL ID: CHEMBL43612CHEBI ID: CHEBI:15794UNII: W6Q80SK9L6HMDB ID: HMDB0030773KEGG ID: C03840METABOLOMICS WORKBENCH ID: 44554WIKIDATA ID: Q900912
Experimental Spectrum References
13C NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c02144Structure-Guided Optimization and Preclinical Evaluation of 6-<i>O</i>-Benzylguanine-Based Pin1 Inhibitor for Hepatocellular Carcinoma Treatment.DOI 10.1021/acsmedchemlett.4c00477Discovery of Novel Pyrimidine Derivatives as Human Pin1 Covalent Inhibitors.DOI 10.1039/D4MD00558AGeneration and capture of naphthoquinonynes: a new frontier in the development of trypanocidal quinones <i>via</i> aryne chemistry.PMID 39512946Generation and capture of naphthoquinonynes: a new frontier in the development of trypanocidal quinones <i>via</i> aryne chemistry.PMID 39811131Discovery of Novel Pyrimidine Derivatives as Human Pin1 Covalent Inhibitors.PMID 39868498Structure-Guided Optimization and Preclinical Evaluation of 6-<i>O</i>-Benzylguanine-Based Pin1 Inhibitor for Hepatocellular Carcinoma Treatment.DOI 10.1016/j.ejmech.2024.116249Unlocking the potential of 1,4-naphthoquinones: A comprehensive review of their anticancer properties.DOI 10.1016/j.ejmech.2024.116338Structure-based discovery of potent myosin inhibitors to guide antiparasite drug development.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

1,8-DihydroxyanthraquinoneCAS 117-10-2
2,3',4,6-TetrahydroxybenzophenoneCAS 26271-33-0
3-Hydroxy-4H-pyran-4-oneCAS 496-63-9
Alkannin beta,beta-dimethylacrylateCAS 34539-65-6
2,5-Dihydroxybenzoic acidCAS 490-79-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 117-10-21,8-DihydroxyanthraquinoneCAS 520-36-5ApigeninCAS 118-75-2ChloranilCAS 1239-45-8Ethidium BromideCAS 302-79-4Retinoic AcidCAS 114-07-8ErythromycinCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 481-39-0

What are the key identifiers for Juglone (CAS 481-39-0)?

Juglone is identified by CAS 481-39-0, with molecular formula C10H6O3, molecular weight 174.15, InChIKey KQPYUDDGWXQXHS-UHFFFAOYSA-N.

Does CAS 481-39-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Tyrosyl-DNA phosphodiesterase 1, Protein disulfide-isomerase, ATP-dependent DNA helicase Q1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Microtubule-associated protein tau. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 481-39-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Juglone?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 481-39-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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