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Home/Compounds/CAS 483-63-6
Formula C13H17NOMW 203.28Research-use catalog entryCOA/SDS by request

Crotamiton

CAS Number: 483-63-6

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100 g
Purity
95%
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25 g
Purity
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5 g
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Loading RDKit molecule structure...
InChIKey: DNTGGZPQPQTDQF-UHFFFAOYSA-NC13H17NO | MW 203.28

Chemical Absolute Identifiers

CAS Number

483-63-6

PubChem CID

2883

Molecular Formula

C13H17NO

Molecular Weight

203.28 g/mol

Exact Mass

203.131014

InChIKey

DNTGGZPQPQTDQF-UHFFFAOYSA-N

IUPAC Name

N-ethyl-N-(2-methylphenyl)but-2-enamide

SMILES String

CCN(C1=CC=CC=C1C)C(=O)C=CC

Physical Properties

Melting Point

25.0 °C

Water Solubility

0.353 g/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Crotamiton (CAS 483-63-6) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C13H17NO and molecular weight 203. 28 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Cytochrome P450 3A4 (Homo sapiens) — 2 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 3 assays; Cannabinoid receptor 1 (Homo sapiens) — 3 assays; 5-hydroxytryptamine receptor 2A (Homo sapiens) — 2 assays; 5-hydroxytryptamine receptor 2B (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Cytochrome P450 3A4

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.9

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Cannabinoid receptor 1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2A

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2B

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.
  • Avoid contact with skin and eyes.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional institution with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Crotamiton

Names & Synonyms

CrotanCrotamitoneCrotalginCrotamitonumN-ethylcrotono-o-toluidide
Show all synonyms
2-Butenamide, N-ethyl-N-(2-methylphenyl)-crotonyl-N-ethyl-o-toluidineEuraxCrotaglinCrotamiton CRSPrestwick0_000951Prestwick1_000951Spectrum2_001700Spectrum3_001081Spectrum4_001234NCIOpen2_004405KBioGR_001728SPBio_001660SPBio_003091
External Identifiers
EC NUMBER: 207-596-3DSSTOX SUBSTANCE ID: DTXSID6040664CHEMBL ID: CHEMBL3183440CHEMBL ID: CHEMBL6067975DRUGBANK ID: DB00265HMDB ID: HMDB0014410METABOLOMICS WORKBENCH ID: 42660NCI THESAURUS CODE: C65353PHARMGKB ID: PA164745460RXCUI: 21766WIKIDATA ID: Q60062768
Experimental Spectrum References
1H NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR SpectraRaman Spectra — Forensic Spectral ResearchUV-VIS SpectraVapor Phase IR Spectra
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.1101/2020.04.03.023846In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replicationDOI 10.1101/2020.04.21.054387Identification of potential treatments for COVID-19 through artificial intelligence-enabled phenomic analysis of human cells infected with SARS-CoV-2DOI 10.1124/mol.112.084152Structure-based identification of OATP1B1/3 inhibitors.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

N,N-diethyl-m-toluamideCAS 134-62-3

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 111974-69-7QuetiapineCAS 114-07-8ErythromycinCAS 13710-19-5Tolfenamic AcidCAS 104227-87-4FamciclovirCAS 112811-59-3GatifloxacinCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 483-63-6

What are the key identifiers for Crotamiton (CAS 483-63-6)?

Crotamiton is identified by CAS 483-63-6, with molecular formula C13H17NO, molecular weight 203.28, InChIKey DNTGGZPQPQTDQF-UHFFFAOYSA-N.

Does CAS 483-63-6 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Cytochrome P450 3A4, Alpha-1A adrenergic receptor, Cannabinoid receptor 1, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 483-63-6?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Crotamiton?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 483-63-6 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

Can MolGraph support bulk sourcing or custom synthesis review?

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