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Home/Compounds/CAS 495-18-1
Formula C7H7NO2MW 137.14Research-use catalog entryCOA/SDS by request

Benzohydroxamic acid

CAS Number: 495-18-1

Sourcing & RFQ

Submit an RFQ to review pricing, availability, lead time, pack size, purity, COA, and supplier SDS for this catalog entry.

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Availability
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COA/SDS available on request
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Public pricing is not shown for this CAS. Submit an RFQ to confirm availability, documentation, and shipping review.

Loading RDKit molecule structure...
InChIKey: VDEUYMSGMPQMIK-UHFFFAOYSA-NC7H7NO2 | MW 137.14

Chemical Absolute Identifiers

CAS Number

495-18-1

PubChem CID

10313

Molecular Formula

C7H7NO2

Molecular Weight

137.14 g/mol

Exact Mass

137.047678

InChIKey

VDEUYMSGMPQMIK-UHFFFAOYSA-N

IUPAC Name

N-hydroxybenzamide

SMILES String

C1=CC=C(C=C1)C(=O)NO

Physical Properties

Appearance

Rhombic crystals or light beige solid. (NTP, 1992)

Melting Point

126.11–13 °C

Water Solubility

5 mol/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Benzohydroxamic acid (CAS 495-18-1) is listed in the Advanced Chemicals portfolio, with molecular formula C7H7NO2 and molecular weight 137. 14 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Organic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Protein deacetylase HDAC6 (Homo sapiens) — 4 assays; Histone deacetylase 1 (Homo sapiens) — 4 assays; Androgen receptor (Homo sapiens) — 2 assays; Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 4 documents · best pChEMBL 6.94

Experimental evidence source: ChEMBL

Histone deacetylase 1

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 4 documents · best pChEMBL 5.33

Experimental evidence source: ChEMBL

Androgen receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Tyrosyl-DNA phosphodiesterase 1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • and reactivity.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • The product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
Show additional safety reference fields

Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Benzohydroxamic acid

Names & Synonyms

Benzhydroxamic acidBenzamide, N-hydroxy-Phenylhydroxamic acidBenzoylhydroxamic acidHydroxylamine, N-benzoyl-
Show all synonyms
N-Hydroxy-benzamideBenzohydroxamateBenzohyroxamatebenzenecarbohydroxamic acidN-BenzoylhydroxylamineBHOCCRIS 6046benzohydroxamicbenzohydroxamsaure3uxkbenzoylhydroxylaminebenzoylamino-alcoholBenzenecarboximidic acid, N-hydroxy-, (Z)- (9CI)hydroxyphenyl nitrone
External Identifiers
EC NUMBER: 207-797-6DSSTOX SUBSTANCE ID: DTXSID7025421CHEMBL ID: CHEMBL16300UNII: K8YW73872DDRUGBANK ID: DB01924HMDB ID: HMDB0255153METABOLOMICS WORKBENCH ID: 146541WIKIDATA ID: Q27093030
Experimental Spectrum References
13C NMR Spectra15N NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR SpectraFTIR SpectraUV-VIS Spectra
Literature & Patent References
DOI 10.1021/acsmedchemlett.2c00272Fragment-Based Discovery of a Novel, Brain Penetrant, Orally Active HDAC2 Inhibitor.PMID 36262388Fragment-Based Discovery of a Novel, Brain Penetrant, Orally Active HDAC2 Inhibitor.DOI 10.1021/acsmedchemlett.1c00425Role of Fluorination in the Histone Deacetylase 6 (HDAC6) Selectivity of Benzohydroxamate-Based Inhibitors.PMID 34795871Role of Fluorination in the Histone Deacetylase 6 (HDAC6) Selectivity of Benzohydroxamate-Based Inhibitors.DOI 10.1016/j.bmcl.2019.06.006Synthesis of N'-propylhydrazide analogs of hydroxamic inhibitors of histone deacetylases (HDACs) and evaluation of their impact on activities of HDACs and replication of hepatitis C virus (HCV).DOI 10.1021/acs.jmedchem.9b01194Novel Benzohydroxamate-Based Potent and Selective Histone Deacetylase 6 (HDAC6) Inhibitors Bearing a Pentaheterocyclic Scaffold: Design, Synthesis, and Biological Evaluation.PMID 31201063Synthesis of N'-propylhydrazide analogs of hydroxamic inhibitors of histone deacetylases (HDACs) and evaluation of their impact on activities of HDACs and replication of hepatitis C virus (HCV).PMID 31710483Novel Benzohydroxamate-Based Potent and Selective Histone Deacetylase 6 (HDAC6) Inhibitors Bearing a Pentaheterocyclic Scaffold: Design, Synthesis, and Biological Evaluation.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

Isonicotinohydroxamic acidCAS 4427-22-9
4-Chlorobenzenehydroxamic acidCAS 1613-88-3
Sodium benzamidooxidanide--water (1/1/1)CAS 22513-32-2
Salicylhydroxamic AcidCAS 89-73-6
N,3,4-TrihydroxybenzamideCAS 69839-83-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 4427-22-9Isonicotinohydroxamic acidCAS 1613-88-34-Chlorobenzenehydroxamic acidCAS 22513-32-2Sodium benzamidooxidanide--water (1/1/1)CAS 89-73-6Salicylhydroxamic AcidCAS 69839-83-4N,3,4-TrihydroxybenzamideCAS 112574-44-4NitrofurazoneCAS 128517-07-7RomidepsinCAS 13710-19-5Tolfenamic AcidCAS 149647-78-9VorinostatCAS 622-30-0Benzylhydroxylamine

RFQ questions for CAS 495-18-1

What are the key identifiers for Benzohydroxamic acid (CAS 495-18-1)?

Benzohydroxamic acid is identified by CAS 495-18-1, with molecular formula C7H7NO2, molecular weight 137.14, InChIKey VDEUYMSGMPQMIK-UHFFFAOYSA-N.

Does CAS 495-18-1 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Protein deacetylase HDAC6, Histone deacetylase 1, Androgen receptor, Tyrosyl-DNA phosphodiesterase 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 495-18-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Benzohydroxamic acid?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 495-18-1 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

Can MolGraph support bulk sourcing or custom synthesis review?

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