MolGraph
CompoundsDocumentationComplianceAbout
MolGraph

Research chemical sourcing and molecular building block RFQ workflows.

MolGraph is operated by Tessorix Inc.

support@molgraph.com

Products are intended for laboratory research use only and are not for human or veterinary use.

Compounds

  • Compound catalog
  • CAS Search

Company

  • About
  • Contact

Documentation

  • Quality Documentation
  • SDS Disclaimer

Compliance

  • Compliance

Legal

  • Terms
  • Privacy

Copyright © 2026 MolGraph. All Rights Reserved.

Home/Compounds/CAS 50-65-7
Formula C13H8Cl2N2O4MW 327.12Research-use catalog entryCOA/SDS by request

Niclosamide

CAS Number: 50-65-7

Sourcing & RFQ

Submit an RFQ to review pricing, availability, lead time, pack size, purity, COA, and supplier SDS for this catalog entry.

Available options

Available Options

Package
1 kg
Purity
98%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
1 mg
Purity
98%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
100 g
Purity
98%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
25 g
Purity
98%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
3.44 g
Purity
98%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
5 g
Purity
98%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
500 g
Purity
98%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required

Shipping review is required before pricing or stock can be confirmed publicly. Shipping, duties, and documentation fees are confirmed before order acceptance.

Loading RDKit molecule structure...
InChIKey: RJMUSRYZPJIFPJ-UHFFFAOYSA-NC13H8Cl2N2O4 | MW 327.12

Chemical Absolute Identifiers

CAS Number

50-65-7

PubChem CID

4477

Molecular Formula

C13H8Cl2N2O4

Molecular Weight

327.12 g/mol

Exact Mass

325.986112

InChIKey

RJMUSRYZPJIFPJ-UHFFFAOYSA-N

IUPAC Name

5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide

SMILES String

C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O

Physical Properties

Melting Point

225–23 °C

Show more physical data

Vapor Pressure

Estimated value, unit not specified

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Niclosamide (CAS 50-65-7) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C13H8Cl2N2O4 and molecular weight 327. 12 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Muscarinic acetylcholine receptor M1 (Rattus norvegicus) — 2 assays; Prelamin-A/C (Homo sapiens) — 2 assays; Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens) — 3 assays; Thrombopoietin (Homo sapiens) — 2 assays; Signal transducer and activator of transcription 3 (Homo sapiens) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Muscarinic acetylcholine receptor M1

Rattus norvegicus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 8.74

Experimental evidence source: ChEMBL

Prelamin-A/C

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 7.6

Experimental evidence source: ChEMBL

Tyrosyl-DNA phosphodiesterase 1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 7.4

Experimental evidence source: ChEMBL

Thrombopoietin

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 7

Experimental evidence source: ChEMBL

Signal transducer and activator of transcription 3

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 6.68

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction stability.
  • Carbon monoxide, carbon dioxide, hydrogen chloride, nitrogen oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
Show additional safety reference fields

Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Niclosamide

Names & Synonyms

NiclocideCestocidMansonilPhenasalTredemine
Show all synonyms
VermitidFenasalLintexNasemoSulquiYomesanDeverminDevermineHelmiantinRadevermAtenaseIomesanIomezanSagimid
External Identifiers
EC NUMBER: 200-056-8DSSTOX SUBSTANCE ID: DTXSID7040362CHEMBL ID: CHEMBL1448CHEBI ID: CHEBI:7553UNII: 8KK8CQ2K8GDRUGBANK ID: DB06803HMDB ID: HMDB0015679KEGG ID: D00436METABOLOMICS WORKBENCH ID: 43707NCI THESAURUS CODE: C66240PHARMGKB ID: PA165958408WIKIDATA ID: Q418523
Experimental Spectrum References
FTIR SpectraRaman Spectra
Literature & Patent References
DOI 10.1016/j.bmc.2025.118114Discovery of niclosamide as a p300/transcription factor protein-protein interaction inhibitor.DOI 10.1021/acs.jmedchem.4c01368Modulation of Mitochondria-Endoplasmic Reticulum Contacts (MERCs) by Small Molecules as a New Strategy for Restoring Lipid Metabolism in an Amyotrophic Lateral Sclerosis Model.PMID 39778888Modulation of Mitochondria-Endoplasmic Reticulum Contacts (MERCs) by Small Molecules as a New Strategy for Restoring Lipid Metabolism in an Amyotrophic Lateral Sclerosis Model.PMID 39970485Discovery of niclosamide as a p300/transcription factor protein-protein interaction inhibitor.DOI 10.1016/j.ejmech.2023.115978Design, synthesis and biological evaluation of biaryl amide derivatives against SARS-CoV-2 with dual-target mechanism.DOI 10.1016/j.ejmech.2023.116040Targeted regulated cell death with small molecule compounds in colorectal cancer: Current perspectives of targeted therapy and molecular mechanisms.DOI 10.1016/j.ejmech.2024.116833Drug repurposing against antibiotic resistant bacterial pathogens.DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

AklomideCAS 3011-89-0
ClosantelCAS 57808-65-8
Closantel sodiumCAS 61438-64-0
DinitolmideCAS 148-01-6
SU-11652CAS 326914-10-7

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 3011-89-0AklomideCAS 23593-75-1ClotrimazoleCAS 21829-25-4NifedipineCAS 79794-75-5LoratadineCAS 100643-71-8DesloratadineCAS 102767-28-2LevetiracetamCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 50-65-7

What are the key identifiers for Niclosamide (CAS 50-65-7)?

Niclosamide is identified by CAS 50-65-7, with molecular formula C13H8Cl2N2O4, molecular weight 327.12, InChIKey RJMUSRYZPJIFPJ-UHFFFAOYSA-N.

Does CAS 50-65-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Muscarinic acetylcholine receptor M1, Prelamin-A/C, Tyrosyl-DNA phosphodiesterase 1, Thrombopoietin, Signal transducer and activator of transcription 3. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 50-65-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Niclosamide?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 50-65-7 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

Can MolGraph support bulk sourcing or custom synthesis review?

Submit the CAS number, quantity, purity requirement, and destination country for sourcing review.