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Home/Compounds/CAS 501684-93-1
Formula C14H9Cl2F3N2O2MW 365.1Research-use catalog entryCOA/SDS by request

NS-1738

CAS Number: 501684-93-1

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Loading RDKit molecule structure...
InChIKey: OUDXRNQPVSMGDW-UHFFFAOYSA-NC14H9Cl2F3N2O2 | MW 365.1

Chemical Absolute Identifiers

CAS Number

501684-93-1

PubChem CID

310378

Molecular Formula

C14H9Cl2F3N2O2

Molecular Weight

365.1 g/mol

Exact Mass

363.999317

InChIKey

OUDXRNQPVSMGDW-UHFFFAOYSA-N

IUPAC Name

1-(5-chloro-2-hydroxyphenyl)-3-[2-chloro-5-(trifluoromethyl)phenyl]urea

SMILES String

C1=CC(=C(C=C1C(F)(F)F)NC(=O)NC2=C(C=CC(=C2)Cl)O)Cl

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

NS-1738 (CAS 501684-93-1) is listed in the Advanced Chemicals portfolio, with molecular formula C14H9Cl2F3N2O2 and molecular weight 365. 10 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Organic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Neuronal acetylcholine receptor subunit alpha-7

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 5.47

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

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  • Store in a well-ventilated place.
  • Recommended storage conditions: keep away from light, purge, room temperature.

PPE

Respiratory protection if needed

First Aid

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  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity.
  • Carbon monoxide, carbon dioxide, hydrogen chloride, hydrogen fluoride, nitrogen oxides.

Disposal

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  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

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Accidental Release

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  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

NS-1738

Names & Synonyms

1-(5-chloro-2-hydroxyphenyl)-3-(2-chloro-5-(trifluoromethyl)phenyl)ureaUrea, N-(5-chloro-2-hydroxyphenyl)-N'-(2-chloro-5-(trifluoromethyl)phenyl)-N-(5-CHLORO-2-HYDROXYPHENYL)-N'-[2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL]UREA3-(5-chloro-2-hydroxyphenyl)-1-[2-chloro-5-(trifluoromethyl)phenyl]urea3-(5-chloro-2-hydroxyphenyl)-1-(2-chloro-5-(trifluoromethyl)phenyl)urea
Show all synonyms
N-(5-Chloro-2-hydroxyphenyl)-N'-(2-chloro-5-(trifluoromethyl)phenyl)ureaNS 17381-(5-chloro-2-hydroxy-phenyl)-3-(2-chloro-5-trifluoromethyl-phenyl)-urea1-(5-chloro-2-hydroxy-phenyl)-3-[2-chloro-5-(trifluoromethyl)phenyl]ureaN-(3-Chloro-6-hydroxy-phenyl)-N'-(2-chloro-5-trifluoromethyl-phenyl)ureaXG3
External Identifiers
EC NUMBER: 803-753-0DSSTOX SUBSTANCE ID: DTXSID50309712CHEMBL ID: CHEMBL407217UNII: 9822RX831LWIKIDATA ID: Q27088051
Literature & Patent References
DOI 10.1021/acs.jmedchem.3c02323Allosteric Activation of α7 Nicotinic Acetylcholine Receptors by Novel 2-Arylamino-thiazole-5-carboxylic Acid Amide Derivatives for the Improvement of Cognitive Deficits in Mice.PMID 38393821Allosteric Activation of α7 Nicotinic Acetylcholine Receptors by Novel 2-Arylamino-thiazole-5-carboxylic Acid Amide Derivatives for the Improvement of Cognitive Deficits in Mice.DOI 10.1021/acs.jmedchem.1c01058Synthesis and Biological Evaluation of Novel Triazine Derivatives as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors.PMID 34374537Synthesis and Biological Evaluation of Novel Triazine Derivatives as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors.DOI 10.1021/acs.jmedchem.9b01569Discovery of Novel, Potent, Brain-Permeable, and Orally Efficacious Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptor [4-(5-(4-Chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide]: Structure-Activity Relationship and Preclinical Characterization.PMID 31755711Discovery of Novel, Potent, Brain-Permeable, and Orally Efficacious Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptor [4-(5-(4-Chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide]: Structure-Activity Relationship and Preclinical Characterization.DOI 10.1021/jm070256gAllosteric modulators of the alpha7 nicotinic acetylcholine receptor.PMID 18198823Allosteric modulators of the alpha7 nicotinic acetylcholine receptor.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

NS-1643CAS 448895-37-2
N,N'-Di-(m-trifluoromethylphenyl)ureaCAS 403-96-3
NS-1652CAS 1566-81-0
3,3',4,4'-TetrachlorocarbanilideCAS 4300-43-0
4,4'-DichlorocarbanilideCAS 1219-99-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 448895-37-2NS-1643CAS 403-96-3N,N'-Di-(m-trifluoromethylphenyl)ureaCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 501684-93-1

What are the key identifiers for NS-1738 (CAS 501684-93-1)?

NS-1738 is identified by CAS 501684-93-1, with molecular formula C14H9Cl2F3N2O2, molecular weight 365.1, InChIKey OUDXRNQPVSMGDW-UHFFFAOYSA-N.

Does CAS 501684-93-1 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Neuronal acetylcholine receptor subunit alpha-7. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 501684-93-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for NS-1738?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 501684-93-1 available for quotation?

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