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Home/Compounds/CAS 51773-92-3
Formula C17H17ClF6N2OMW 414.8Research-use catalog entryCOA/SDS by request

Mefloquine Hydrochloride

CAS Number: 51773-92-3

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Loading RDKit molecule structure...
InChIKey: WESWYMRNZNDGBX-YLCXCWDSSA-NC17H17ClF6N2O | MW 414.8

Chemical Absolute Identifiers

CAS Number

51773-92-3

PubChem CID

65329

Molecular Formula

C17H17ClF6N2O

Molecular Weight

414.8 g/mol

Exact Mass

414.09336

InChIKey

WESWYMRNZNDGBX-YLCXCWDSSA-N

IUPAC Name

(S)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2R)-piperidin-2-yl]methanol;hydrochloride

SMILES String

C1CCN[C@H](C1)[C@H](C2=CC(=NC3=C2C=CC=C3C(F)(F)F)C(F)(F)F)O.Cl

Physical Properties

Water Solubility

62.2 mol/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Mefloquine Hydrochloride (CAS 51773-92-3) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C17H17ClF6N2O and molecular weight 414. 80 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Geminin (Homo sapiens) — 2 assays; Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Geminin

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Tyrosyl-DNA phosphodiesterase 1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, hydrogen chloride, hydrogen fluoride, nitrogen oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Mefloquine Hydrochloride

Names & Synonyms

Mefloquine HCLMephaquinLoriamRo 21-5998/001Ro-21-5998/001
Show all synonyms
Mefloquini hydrochloridum(S)-(2,8-bis(trifluoromethyl)quinolin-4-yl)-((2R)-piperidin-2-yl)methanolMefloquine hydrochloride, (+)Mefloquine (hydrochloride)4-Quinolinemethanol, a-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-,monohydrochloride, (aS)-rel-rel-(S)-(2,8-Bis(trifluoromethyl)quinolin-4-yl)((R)-piperidin-2-yl)methanol hydrochloride(S)-[2,8-bis(trifluoromethyl)quinolin-4-yl][(2R)-piperidin-2-yl]methanol hydrochloride4-QUINOLINEMETHANOL, ALPHA-(2R)-2-PIPERIDINYL-2,8-BIS(TRIFLUOROMETHYL)-, HYDROCHLORIDE (1:1), (ALPHAS)-REL-WR 142490 hydrochlorideMefloquinehydrochlorideMefloquine hydrochloride [USAN]Mefloquin HydrochlorideC17H17ClF6N2O
External Identifiers
EC NUMBER: 257-412-0DSSTOX SUBSTANCE ID: DTXSID1047819CHEMBL ID: CHEMBL1606CHEMBL ID: CHEMBL535650CHEBI ID: CHEBI:6719UNII: 326VC85GV6UNII: 5Y9L3636O3KEGG ID: D00831NCI THESAURUS CODE: C47600RXCUI: 82130WIKIDATA ID: Q72488310Ro-215998001Ro-21-5998
Literature & Patent References
DOI 10.1016/j.ejmech.2021.113981Design, synthesis, and characterization of novel aminoalcohol quinolines with strong in vitro antimalarial activity.PMID 34782182Design, synthesis, and characterization of novel aminoalcohol quinolines with strong in vitro antimalarial activity.DOI 10.1021/acs.jnatprod.9b00647Antimalarial 9-Methoxystrobilurins, Oudemansins, and Related Polyketides from Cultures of Basidiomycete <i>Favolaschia</i> Species.DOI 10.1021/acs.jnatprod.9b00947Highly Modified Lanostane Triterpenes from the Wood-Rot Basidiomycete Ganoderma colossus: Comparative Chemical Investigations of Natural and Artificially Cultivated Fruiting Bodies and Mycelial Cultures.PMID 32193929Antimalarial 9-Methoxystrobilurins, Oudemansins, and Related Polyketides from Cultures of Basidiomycete <i>Favolaschia</i> Species.PMID 32639735Highly Modified Lanostane Triterpenes from the Wood-Rot Basidiomycete Ganoderma colossus: Comparative Chemical Investigations of Natural and Artificially Cultivated Fruiting Bodies and Mycelial Cultures.DOI 10.1021/jm40060774-Amino-7-chloroquinolines: probing ligand efficiency provides botulinum neurotoxin serotype A light chain inhibitors with significant antiprotozoal activity.PMID 238151864-Amino-7-chloroquinolines: probing ligand efficiency provides botulinum neurotoxin serotype A light chain inhibitors with significant antiprotozoal activity.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 6959-47-3Picolyl chloride hydrochlorideCAS 10083-24-6PiceatannolCAS 112574-44-4NitrofurazoneCAS 1148-79-42,2':6',2''-TerpyridineCAS 118-10-5(S)-Quinolin-4-yl((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanol , CinchonineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 51773-92-3

What are the key identifiers for Mefloquine Hydrochloride (CAS 51773-92-3)?

Mefloquine Hydrochloride is identified by CAS 51773-92-3, with molecular formula C17H17ClF6N2O, molecular weight 414.8, InChIKey WESWYMRNZNDGBX-YLCXCWDSSA-N.

Does CAS 51773-92-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Geminin, Tyrosyl-DNA phosphodiesterase 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 51773-92-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Mefloquine Hydrochloride?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 51773-92-3 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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