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Home/Compounds/CAS 520-36-5
Formula C15H10O5MW 270.24Research-use catalog entryCOA/SDS by request

Apigenin

CAS Number: 520-36-5

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Loading RDKit molecule structure...
InChIKey: KZNIFHPLKGYRTM-UHFFFAOYSA-NC15H10O5 | MW 270.24

Chemical Absolute Identifiers

CAS Number

520-36-5

PubChem CID

5280443

Molecular Formula

C15H10O5

Molecular Weight

270.24 g/mol

Exact Mass

270.052823

InChIKey

KZNIFHPLKGYRTM-UHFFFAOYSA-N

IUPAC Name

5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one

SMILES String

O=c1cc(-c2ccc(O)cc2)oc2cc(O)cc(O)c12

Physical Properties

Melting Point

345–35 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Apigenin (CAS 520-36-5) is listed in the Life Science portfolio, with molecular formula C15H10O5 and molecular weight 270. 24 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for life-science research and analytical workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Life Science ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Acetylcholinesterase (Homo sapiens) — 3 assays; Cytochrome P450 1B1 (Homo sapiens) — 4 assays; Cytochrome P450 1A2 (Homo sapiens) — 3 assays; Transthyretin (Homo sapiens) — 4 assays; MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Acetylcholinesterase

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 7.92

Experimental evidence source: ChEMBL

Cytochrome P450 1B1

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 4 documents · best pChEMBL 7.6

Experimental evidence source: ChEMBL

Cytochrome P450 1A2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 7.2

Experimental evidence source: ChEMBL

Transthyretin

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 6.6

Experimental evidence source: ChEMBL

MAP kinase-interacting serine/threonine-protein kinase 2

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.51

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Apigenin

Names & Synonyms

5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-oneVersulinApigenol4',5,7-TrihydroxyflavoneApigenine
Show all synonyms
SpigeninC.I. Natural Yellow 15,7,4'-Trihydroxyflavone5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-onePelargidenon 14494H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-2-(p-Hydroxyphenyl)-5,7-dihydroxychromone5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyroneFLAVONE, 4',5,7-TRIHYDROXY-Chamomile oil, germanUCCF 031Apigenin (Standard)4',5,7-TrihydroxyflavaoneCCRIS 3789
External Identifiers
EC NUMBER: 208-292-3EC NUMBER: 628-919-8DSSTOX SUBSTANCE ID: DTXSID6022391CHEMBL ID: CHEMBL28CHEBI ID: CHEBI:18388UNII: 7V515PI7F6DRUGBANK ID: DB07352HMDB ID: HMDB0002124KEGG ID: C01477METABOLOMICS WORKBENCH ID: 23090NCI THESAURUS CODE: C68466RXCUI: 1368130WIKIDATA ID: Q424567
Experimental Spectrum References
13C NMR Spectra1H NMR SpectraATR-IR Spectra — Forensic Spectral ResearchRaman Spectra — Forensic Spectral ResearchUV Spectra
Literature & Patent References
DOI 10.1016/j.bmc.2025.118106Research progress of flavonoids targeting estrogen receptor in the treatment of breast cancer.DOI 10.1016/j.ejmech.2024.117008Multidrug-resistant bacteria quorum-sensing inhibitors: A particular focus on Pseudomonasaeruginosa.DOI 10.1016/j.ejmech.2024.117012Understanding the synergistic sensitization of natural products and antibiotics: An effective strategy to combat MRSA.DOI 10.1016/j.ejmech.2025.117650Fluorinated sulfonamide-flavonoid derivatives as novel Keap1-Nrf2 inhibitors: Potent induction of cytoprotective gene HO-1 in vivo.DOI 10.1021/acs.jmedchem.4c01116In Search for Inhibitors of Human Aldo-Keto Reductase 1B10 (AKR1B10) as Novel Agents to Fight Cancer and Chemoresistance: Current State-of-the-Art and Prospects.DOI 10.1021/acs.jmedchem.4c02717Recent Progress in the Development of Glucose Transporter (GLUT) Inhibitors.DOI 10.1021/acs.jmedchem.4c03124Discovery of the 2,3-Dihydrobenzopyrane-4-one as a Potent FTO Inhibitor against Obesity-Related Metabolic Diseases.PMID 39500066Multidrug-resistant bacteria quorum-sensing inhibitors: A particular focus on Pseudomonasaeruginosa.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

ScutellareinCAS 529-53-3
HispidulinCAS 1447-88-7
Luteolin 7-methyl etherCAS 20243-59-8
GalanginCAS 548-83-4
VitexinCAS 3681-93-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 529-53-3ScutellareinCAS 1447-88-7HispidulinCAS 20243-59-8Luteolin 7-methyl etherCAS 548-83-4GalanginCAS 3681-93-4VitexinCAS 21829-25-4NifedipineCAS 23593-75-1ClotrimazoleCAS 50-65-7NiclosamideCAS 528-48-3FisetinCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamate

RFQ questions for CAS 520-36-5

What are the key identifiers for Apigenin (CAS 520-36-5)?

Apigenin is identified by CAS 520-36-5, with molecular formula C15H10O5, molecular weight 270.24, InChIKey KZNIFHPLKGYRTM-UHFFFAOYSA-N.

Does CAS 520-36-5 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Acetylcholinesterase, Cytochrome P450 1B1, Cytochrome P450 1A2, Transthyretin, MAP kinase-interacting serine/threonine-protein kinase 2. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 520-36-5?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Apigenin?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 520-36-5 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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