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Home/Compounds/CAS 53179-13-8
Formula C12H11NOMW 185.22Research-use catalog entryCOA/SDS by request

Pirfenidone

CAS Number: 53179-13-8

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Loading RDKit molecule structure...
InChIKey: ISWRGOKTTBVCFA-UHFFFAOYSA-NC12H11NO | MW 185.22

Chemical Absolute Identifiers

CAS Number

53179-13-8

PubChem CID

40632

Molecular Formula

C12H11NO

Molecular Weight

185.22 g/mol

Exact Mass

185.084064

InChIKey

ISWRGOKTTBVCFA-UHFFFAOYSA-N

IUPAC Name

5-methyl-1-phenylpyridin-2-one

SMILES String

CC1=CN(C(=O)C=C1)C2=CC=CC=C2

Physical Properties

Melting Point

102–104 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Pirfenidone (CAS 53179-13-8) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C12H11NO and molecular weight 185. 22 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: RecQ-like DNA helicase BLM (Homo sapiens) — 2 assays; 5-hydroxytryptamine receptor 2A (Homo sapiens) — 3 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 3 assays; Histamine H1 receptor (Homo sapiens) — 3 assays; Nuclear receptor subfamily 1 group I member 2 (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

RecQ-like DNA helicase BLM

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 7.15

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2A

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Histamine H1 receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Nuclear receptor subfamily 1 group I member 2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • The product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Use personal protective equipment and emergency procedures.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Pirfenidone

Names & Synonyms

EsbrietPirespaPirfenidonaPirfenidonum2(1H)-Pyridinone, 5-methyl-1-phenyl-
Show all synonyms
5-Methyl-1-phenyl-2(1H)-pyridoneAMR 69ESBRIET COMPONENT PIRFENIDONE5-METHYL-1-PHENYL-1,2-DIHYDROPYRIDIN-2-ONE5-methyl-1-phenylpyridin-2(1H)-one5-methyl-1-phenyl-2(1H)-pyridinone5-Methyl-1-phenyl-2-(1H)-pyridoneDeskar5-Methyl-1-phenyl-2-pyridone5-methyl-1-phenyl-2-pyridinone5-Methyl-N-phenyl-2-1H-pyridone [Pirfenidone]Pirfenidone [USAN:INN]Pirfenidonum [INN-Latin]Pirfenidona [INN-Spanish]
External Identifiers
EC NUMBER: 621-260-7DSSTOX SUBSTANCE ID: DTXSID4045183CHEMBL ID: CHEMBL1256391CHEBI ID: CHEBI:32016UNII: D7NLD2JX7UDRUGBANK ID: DB04951HMDB ID: HMDB0256594KEGG ID: D01583METABOLOMICS WORKBENCH ID: 149350NCI THESAURUS CODE: C2635PHARMGKB ID: PA166249581RXCUI: 1592254WIKIDATA ID: Q2060696
Experimental Spectrum References
ATR-IR Spectra — Forensic Spectral ResearchFTIR Spectra — Forensic Spectral ResearchRaman Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1016/j.ejmech.2024.116608Discovery of novel pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione (PBD) derivatives as selective HDAC6 inhibitors for the efficient treatment of idiopathic pulmonary fibrosis (IPF) in vitro and in vivo.DOI 10.1021/acs.jmedchem.4c01533Discovery of Selective PDE1 Inhibitors with Anti-pulmonary Fibrosis Effects by Targeting the Metal Pocket.DOI 10.1021/acs.jnatprod.4c00422Discovery of Oxidized <i>p</i>-Terphenyls as Phosphodiesterase 4 Inhibitors from Marine-Derived Fungi.PMID 38905805Discovery of novel pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione (PBD) derivatives as selective HDAC6 inhibitors for the efficient treatment of idiopathic pulmonary fibrosis (IPF) in vitro and in vivo.PMID 38943602Discovery of Oxidized <i>p</i>-Terphenyls as Phosphodiesterase 4 Inhibitors from Marine-Derived Fungi.PMID 39546471Discovery of Selective PDE1 Inhibitors with Anti-pulmonary Fibrosis Effects by Targeting the Metal Pocket.DOI 10.1021/acs.jmedchem.2c01764Design and Discovery of Novel Cyclic Peptides as EDPs-EBP Interaction Inhibitors for the Treatment of Liver Fibrosis.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

2-Hydroxy-5-methylpyridineCAS 1003-68-5
BenzilCAS 134-81-6
Methyl(methylimino)(phenyl)-lambda6-sulfanoneCAS 30004-67-2
IodobenzeneCAS 591-50-4
2-Phenylaminomethylene-malonic acid diethyl esterCAS 54535-22-7

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 21829-25-4NifedipineCAS 114-07-8ErythromycinCAS 181695-72-7ValdecoxibCAS 100643-71-8DesloratadineCAS 102767-28-2LevetiracetamCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 53179-13-8

What are the key identifiers for Pirfenidone (CAS 53179-13-8)?

Pirfenidone is identified by CAS 53179-13-8, with molecular formula C12H11NO, molecular weight 185.22, InChIKey ISWRGOKTTBVCFA-UHFFFAOYSA-N.

Does CAS 53179-13-8 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with RecQ-like DNA helicase BLM, 5-hydroxytryptamine receptor 2A, Alpha-1A adrenergic receptor, Histamine H1 receptor, Nuclear receptor subfamily 1 group I member 2. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 53179-13-8?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Pirfenidone?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 53179-13-8 available for quotation?

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