- Package
- 1 g
- Purity
- 99%
- Price
- Request review
- Availability
- Shipping review required
- Delivery
- Shipping review required
CAS Number: 552292-08-7
Submit an RFQ to review pricing, availability, lead time, pack size, purity, COA, and supplier SDS for this catalog entry.
Available options
Shipping review is required before pricing or stock can be confirmed publicly. Shipping, duties, and documentation fees are confirmed before order acceptance.
CAS Number
552292-08-7
PubChem CID
10311306
Molecular Formula
C25H26F6N2O2
Molecular Weight
500.5 g/mol
Exact Mass
500.189847
InChIKey
FIVSJYGQAIEMOC-ZGNKEGEESA-N
IUPAC Name
(5S,8S)-8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-1,9-diazaspiro[4.5]decan-2-one
SMILES String
C[C@@H](OC[C@@]1(c2ccccc2)CC[C@]2(CCC(=O)N2)CN1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1
No physical property values available.
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Rolapitant (CAS 552292-08-7) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C25H26F6N2O2 and molecular weight 500. 50 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens) — 4 assays; Adhesion G-protein coupled receptor F1 (Homo sapiens) — 3 assays; Alpha-2A adrenergic receptor (Homo sapiens) — 3 assays; Apelin receptor (Homo sapiens) — 3 assays; Beta-2 adrenergic receptor (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
C5a anaphylatoxin chemotactic receptor 1
Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 2 documents
Experimental evidence source: ChEMBL
Adhesion G-protein coupled receptor F1
Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
Alpha-2A adrenergic receptor
Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
Apelin receptor
Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
Beta-2 adrenergic receptor
Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.
Preliminary Safety Reference
For supplier-issued SDS or COA, submit a documentation request.
Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Rolapitant is identified by CAS 552292-08-7, with molecular formula C25H26F6N2O2, molecular weight 500.5, InChIKey FIVSJYGQAIEMOC-ZGNKEGEESA-N.
ChEMBL contains qualifying experimental assay evidence associated with C5a anaphylatoxin chemotactic receptor 1, Adhesion G-protein coupled receptor F1, Alpha-2A adrenergic receptor, Apelin receptor, Beta-2 adrenergic receptor. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
Availability, pack size, lead time, and pricing are confirmed through RFQ.
Submit the CAS number, quantity, purity requirement, and destination country for sourcing review.