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Home/Compounds/CAS 55268-75-2
Formula C16H16N4O8SMW 424.4Research-use catalog entryCOA/SDS by request

Cefuroxime

CAS Number: 55268-75-2

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Loading RDKit molecule structure...
InChIKey: JFPVXVDWJQMJEE-IZRZKJBUSA-NC16H16N4O8S | MW 424.4

Chemical Absolute Identifiers

CAS Number

55268-75-2

PubChem CID

5479529

Molecular Formula

C16H16N4O8S

Molecular Weight

424.4 g/mol

Exact Mass

424.068885

InChIKey

JFPVXVDWJQMJEE-IZRZKJBUSA-N

IUPAC Name

(6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

SMILES String

CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(COC(N)=O)CS[C@H]12)c1ccco1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Cefuroxime (CAS 55268-75-2) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C16H16N4O8S and molecular weight 424. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Progesterone receptor (Homo sapiens) — 2 assays; Nuclear receptor subfamily 1 group I member 2 (Homo sapiens) — 3 assays; Catechol 2,3-dioxygenase (Stenotrophomonas maltophilia) — 15 assays; Metallo-beta-lactamase (Escherichia coli) — 10 assays; Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)) — 9 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Progesterone receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.41

Experimental evidence source: ChEMBL

Nuclear receptor subfamily 1 group I member 2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 5.21

Experimental evidence source: ChEMBL

Catechol 2,3-dioxygenase

Stenotrophomonas maltophilia · SINGLE PROTEIN · 15 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Metallo-beta-lactamase

Escherichia coli · SINGLE PROTEIN · 10 qualifying assays · 2 documents

Experimental evidence source: ChEMBL

Penicillin-binding protein 1A

Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) · SINGLE PROTEIN · 9 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Cefuroxime

Names & Synonyms

CephuroximeCefuroximCefuroximoCefuroximumSharox
Show all synonyms
Zinacef DanmarkCefuroximaCefuroxime Acid(6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-((2-furanyl(methoxyimino)acetyl)amino)-8-oxo-, (6R-(6alpha,7beta(Z)))-(6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid(6R,7R)-3-((carbamoyloxy)methyl)-7-(((2Z)-2-furan-2-yl-2-(methoxyimino)acetyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid(6R,7R)-3-((carbamoyloxy)methyl)-7-((2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid(6R,7R)-3-(carbamoyloxymethyl)-7-(((2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acidZinacefCefuroximum [INN-Latin]Cefuroximo [INN-Spanish]BiofuroksymCefuril
External Identifiers
EC NUMBER: 259-560-1DSSTOX SUBSTANCE ID: DTXSID5022774CHEMBL ID: CHEMBL1436CHEBI ID: CHEBI:3515UNII: O1R9FJ93EDDRUGBANK ID: DB01112HMDB ID: HMDB0015244KEGG ID: C06894KEGG ID: D00262METABOLOMICS WORKBENCH ID: 43339NCI THESAURUS CODE: C61669PHARMGKB ID: PA448868RXCUI: 2194WIKIDATA ID: Q413728
Literature & Patent References
DOI 10.1016/j.bmc.2024.117895Updated pharmaceutical progress on plant antibiotic rhein and its analogs: Bioactivities, structure-activity relationships and future perspectives.DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1021/acs.jmedchem.4c00983Interaction of Cephalosporins with Human Serum Albumin: A Structural Study.PMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 39083648Interaction of Cephalosporins with Human Serum Albumin: A Structural Study.PMID 39259985Updated pharmaceutical progress on plant antibiotic rhein and its analogs: Bioactivities, structure-activity relationships and future perspectives.DOI 10.1016/j.ejmech.2023.115301Highly selective butyrylcholinesterase inhibitors related to Amaryllidaceae alkaloids - Design, synthesis, and biological evaluation.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

Ceftiofur HydrochlorideCAS 103980-44-5
Cefotaxime SodiumCAS 64485-93-4
Cefepime dihydrochloride monohydrateCAS 123171-59-5
Cefmenoxime HydrochlorideCAS 75738-58-8
Cefoselis SulfateCAS 122841-12-7

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 103980-44-5Ceftiofur HydrochlorideCAS 64485-93-4Cefotaxime SodiumCAS 123171-59-5Cefepime dihydrochloride monohydrateCAS 75738-58-8Cefmenoxime HydrochlorideCAS 122841-12-7Cefoselis SulfateCAS 61477-96-1PiperacillinCAS 69-53-4AmpicillinCAS 102767-28-2LevetiracetamCAS 89786-04-9TazobactamCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamate

RFQ questions for CAS 55268-75-2

What are the key identifiers for Cefuroxime (CAS 55268-75-2)?

Cefuroxime is identified by CAS 55268-75-2, with molecular formula C16H16N4O8S, molecular weight 424.4, InChIKey JFPVXVDWJQMJEE-IZRZKJBUSA-N.

Does CAS 55268-75-2 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Progesterone receptor, Nuclear receptor subfamily 1 group I member 2, Catechol 2,3-dioxygenase, Metallo-beta-lactamase, Penicillin-binding protein 1A. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 55268-75-2?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Cefuroxime?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 55268-75-2 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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