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Home/Compounds/CAS 56-86-0
Formula C5H9NO4MW 147.13Research-use catalog entryCOA/SDS by request

L-Glutamic Acid

CAS Number: 56-86-0

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Loading RDKit molecule structure...
InChIKey: WHUUTDBJXJRKMK-VKHMYHEASA-NC5H9NO4 | MW 147.13

Chemical Absolute Identifiers

CAS Number

56-86-0

PubChem CID

33032

Molecular Formula

C5H9NO4

Molecular Weight

147.13 g/mol

Exact Mass

147.053158

InChIKey

WHUUTDBJXJRKMK-VKHMYHEASA-N

IUPAC Name

(2S)-2-aminopentanedioic acid

SMILES String

C(CC(=O)O)[C@@H](C(=O)O)N

Physical Properties

Melting Point

224.0 °C

Boiling Point

175.0 °C

Density

1.54 g/cm³

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

L-Glutamic Acid (CAS 56-86-0) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C5H9NO4 and molecular weight 147. 13 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Metabotropic glutamate receptor 8 (Homo sapiens) — 2 assays; Excitatory amino acid transporter 3 (Homo sapiens) — 5 assays; Metabotropic glutamate receptor 3 (Homo sapiens) — 15 assays; Metabotropic glutamate receptor 3 (Rattus norvegicus) — 3 assays; Glutamate receptor ionotropic, kainate 1 (Rattus norvegicus) — 6 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Metabotropic glutamate receptor 8

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 8.24

Experimental evidence source: ChEMBL

Excitatory amino acid transporter 3

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 5 documents · best pChEMBL 7.29

Experimental evidence source: ChEMBL

Metabotropic glutamate receptor 3

Homo sapiens · SINGLE PROTEIN · 15 qualifying assays · 7 documents · best pChEMBL 7.24

Experimental evidence source: ChEMBL

Metabotropic glutamate receptor 3

Rattus norvegicus · SINGLE PROTEIN · 3 qualifying assays · 2 documents · best pChEMBL 7.24

Experimental evidence source: ChEMBL

Glutamate receptor ionotropic, kainate 1

Rattus norvegicus · SINGLE PROTEIN · 6 qualifying assays · 5 documents · best pChEMBL 6.86

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • and reactivity.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

L-Glutamic Acid

Names & Synonyms

GLUTAMIC ACIDL-glutamate(S)-2-Aminopentanedioic acidGlutamidexAciglut
Show all synonyms
GlutaminolGlutatonL-Glutaminic acidglutacidGlutamicol(S)-Glutamic acidglutaminic acidL-gluL-(+)-glutamic acidGlutamic acid, L-Acido glutamicoAcide glutamiquealpha-aminoglutaric acidAcidum glutamicum
External Identifiers
EC NUMBER: 200-293-7DSSTOX SUBSTANCE ID: DTXSID5020659CHEMBL ID: CHEMBL575060CHEBI ID: CHEBI:16015UNII: 3KX376GY7LDRUGBANK ID: DB00142HMDB ID: HMDB0000148KEGG ID: C00025KEGG ID: D00007METABOLOMICS WORKBENCH ID: 37101NCI THESAURUS CODE: C1115PHARMGKB ID: PA449776RXCUI: 25916
Experimental Spectrum References
13C NMR Spectra1H NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR SpectraRaman Spectra — Bio-Rad Laboratories, Inc.
Literature & Patent References
DOI 10.1016/j.ejmech.2024.116157Synthesis and pharmacological characterization of conformationally restricted 2-amino-Adipic acid analogs and carboxycyclopropyl glycines as selective metabotropic glutamate 2 receptor agonists.DOI 10.1021/acs.jmedchem.3c01811Design, Synthesis, Pharmacology, and In Silico Studies of (1<i>S</i>,2<i>S</i>,3<i>S</i>)-2-((<i>S</i>)-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu<sub>2</sub> Receptor Agonist.DOI 10.1021/acs.jmedchem.4c00652Triazoles in Medicinal Chemistry: Physicochemical Properties, Bioisosterism, and Application.PMID 38170918Design, Synthesis, Pharmacology, and In Silico Studies of (1<i>S</i>,2<i>S</i>,3<i>S</i>)-2-((<i>S</i>)-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu<sub>2</sub> Receptor Agonist.PMID 38245976Synthesis and pharmacological characterization of conformationally restricted 2-amino-Adipic acid analogs and carboxycyclopropyl glycines as selective metabotropic glutamate 2 receptor agonists.PMID 38699796Triazoles in Medicinal Chemistry: Physicochemical Properties, Bioisosterism, and Application.DOI 10.1016/j.ejmech.2023.115251Discovery of phenylcarbamoyl xanthone derivatives as potent neuroprotective agents for treating ischemic stroke.DOI 10.1021/acsmedchemlett.2c00529Discovery of <b>CVN636</b>: A Highly Potent, Selective, and CNS Penetrant mGluR<sub>7</sub> Allosteric Agonist.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

DL-Glutamic acidCAS 617-65-2
N-Phthaloyl-DL-glutamic acidCAS 6349-98-0
N-Phthaloyl-L-glutamineCAS 3343-29-1
4-carbamoyl-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)butanoic acidCAS 7607-72-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 617-65-2DL-Glutamic acidCAS 2259-96-3CyclothiazideCAS 56-84-8L-Aspartic AcidCAS 21829-25-4NifedipineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 56-86-0

What are the key identifiers for L-Glutamic Acid (CAS 56-86-0)?

L-Glutamic Acid is identified by CAS 56-86-0, with molecular formula C5H9NO4, molecular weight 147.13, InChIKey WHUUTDBJXJRKMK-VKHMYHEASA-N.

Does CAS 56-86-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Metabotropic glutamate receptor 8, Excitatory amino acid transporter 3, Metabotropic glutamate receptor 3, Metabotropic glutamate receptor 3, Glutamate receptor ionotropic, kainate 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 56-86-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for L-Glutamic Acid?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 56-86-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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