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Home/Compounds/CAS 57-88-5
Formula C27H46OMW 386.7Research-use catalog entryCOA/SDS by request

Cholesterol

CAS Number: 57-88-5

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Loading RDKit molecule structure...
InChIKey: HVYWMOMLDIMFJA-DPAQBDIFSA-NC27H46O | MW 386.7

Chemical Absolute Identifiers

CAS Number

57-88-5

PubChem CID

5997

Molecular Formula

C27H46O

Molecular Weight

386.7 g/mol

Exact Mass

386.354866

InChIKey

HVYWMOMLDIMFJA-DPAQBDIFSA-N

IUPAC Name

(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

SMILES String

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

Physical Properties

Boiling Point

36.0 °C

Show more physical data

Vapor Pressure

Estimated value, unit not specified

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Cholesterol (CAS 57-88-5) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C27H46O and molecular weight 386. 70 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Nuclear receptor ROR-gamma (Homo sapiens) — 6 assays; Cholesterol 24-hydroxylase (Homo sapiens) — 2 assays; Alpha-synuclein (Homo sapiens) — 11 assays; Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Nuclear receptor ROR-gamma

Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 2 documents · best pChEMBL 7.7

Experimental evidence source: ChEMBL

Cholesterol 24-hydroxylase

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.17

Experimental evidence source: ChEMBL

Alpha-synuclein

Homo sapiens · SINGLE PROTEIN · 11 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Isocitrate dehydrogenase [NADP] cytoplasmic

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

Cholesterol

Names & Synonyms

CholesterinCholesteryl alcoholDytholCordulanDusoline
Show all synonyms
DusoranCholesterineCholestrinCholestrolHydrocerinLidiniteKathroLanolSuper hartolanLidinitCholesterol base HNimco cholesterol base H(-)-Cholesterol3beta-Hydroxycholest-5-ene
External Identifiers
EC NUMBER: 200-353-2DSSTOX SUBSTANCE ID: DTXSID3022401CHEMBL ID: CHEMBL112570CHEBI ID: CHEBI:16113UNII: 97C5T2UQ7JDRUGBANK ID: DB04540HMDB ID: HMDB0000067KEGG ID: C00187KEGG ID: D00040METABOLOMICS WORKBENCH ID: 34361NCI THESAURUS CODE: C369PHARMGKB ID: PA166178639RXCUI: 2438WIKIDATA ID: Q43656Cholest-5-en-3beta-ol
Experimental Spectrum References
13C NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR SpectraRaman Spectra — Forensic Spectral ResearchVapor Phase IR Spectra
Literature & Patent References
DOI 10.1021/acs.jmedchem.2c01025Structure-Activity Relationships of Ligand Binding to Oxysterol-Binding Protein (OSBP) and OSBP-Related Protein 4.PMID 36916802Structure-Activity Relationships of Ligand Binding to Oxysterol-Binding Protein (OSBP) and OSBP-Related Protein 4.DOI 10.1021/acs.jmedchem.1c00562Neuroactive Type-A γ-Aminobutyric Acid Receptor Allosteric Modulator Steroids from the Hypobranchial Gland of Marine Mollusk, <i>Conus geographus</i>.DOI 10.1021/acsmedchemlett.1c00029Covalent Occlusion of the RORγt Ligand Binding Pocket Allows Unambiguous Targeting of an Allosteric Site.DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsPMID 33854703Covalent Occlusion of the RORγt Ligand Binding Pocket Allows Unambiguous Targeting of an Allosteric Site.PMID 33949869Neuroactive Type-A γ-Aminobutyric Acid Receptor Allosteric Modulator Steroids from the Hypobranchial Gland of Marine Mollusk, <i>Conus geographus</i>.DOI 10.1021/acs.jmedchem.0c00958Assessing the Perturbing Effects of Drugs on Lipid Bilayers Using Gramicidin Channel-Based In Silico and In Vitro Assays.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

(-)-Cholesteryl acetateCAS 604-35-3
Dutasteride acidCAS 104239-97-6
Methyl 3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxylateCAS 103335-41-7

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 604-35-3(-)-Cholesteryl acetateCAS 77-52-1(+)-Ursolic AcidCAS 19387-91-8TinidazoleCAS 23593-75-1ClotrimazoleCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 57-88-5

What are the key identifiers for Cholesterol (CAS 57-88-5)?

Cholesterol is identified by CAS 57-88-5, with molecular formula C27H46O, molecular weight 386.7, InChIKey HVYWMOMLDIMFJA-DPAQBDIFSA-N.

Does CAS 57-88-5 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Nuclear receptor ROR-gamma, Cholesterol 24-hydroxylase, Alpha-synuclein, Isocitrate dehydrogenase [NADP] cytoplasmic. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 57-88-5?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Cholesterol?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 57-88-5 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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