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- 1 g
- Purity
- 99%
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CAS Number: 571190-30-2
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CAS Number
571190-30-2
PubChem CID
5330286
Molecular Formula
C24H29N7O2
Molecular Weight
447.5 g/mol
Exact Mass
447.238273
InChIKey
AHJRHEGDXFFMBM-UHFFFAOYSA-N
IUPAC Name
6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one
SMILES String
CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n(C2CCCC2)c1=O
Melting Point
263–266 °C
Boiling Point
711.5 °C
Water Solubility
1 mol/L
pKa
7.4
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Palbociclib (CAS 571190-30-2) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C24H29N7O2 and molecular weight 447. 50 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: CDK6/cyclin D1 (Homo sapiens) — 14 assays; CDK4/Cyclin D3 (Homo sapiens) — 11 assays; Cyclin-dependent kinase 4/cyclin D1 (Homo sapiens) — 31 assays; CDK9/cyclin T1 (Homo sapiens) — 8 assays; CDK6/cyclin D3 (Homo sapiens) — 13 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
CDK6/cyclin D1
Homo sapiens · PROTEIN COMPLEX · 14 qualifying assays · 9 documents · best pChEMBL 9.7
Experimental evidence source: ChEMBL
CDK4/Cyclin D3
Homo sapiens · PROTEIN COMPLEX · 11 qualifying assays · 6 documents · best pChEMBL 9.59
Experimental evidence source: ChEMBL
Cyclin-dependent kinase 4/cyclin D1
Homo sapiens · PROTEIN COMPLEX · 31 qualifying assays · 18 documents · best pChEMBL 9.1
Experimental evidence source: ChEMBL
CDK9/cyclin T1
Homo sapiens · PROTEIN COMPLEX · 8 qualifying assays · 6 documents · best pChEMBL 9
Experimental evidence source: ChEMBL
CDK6/cyclin D3
Homo sapiens · PROTEIN COMPLEX · 13 qualifying assays · 10 documents · best pChEMBL 8.4
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
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Preliminary Safety Reference
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Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Palbociclib is identified by CAS 571190-30-2, with molecular formula C24H29N7O2, molecular weight 447.5, InChIKey AHJRHEGDXFFMBM-UHFFFAOYSA-N.
ChEMBL contains qualifying experimental assay evidence associated with CDK6/cyclin D1, CDK4/Cyclin D3, Cyclin-dependent kinase 4/cyclin D1, CDK9/cyclin T1, CDK6/cyclin D3. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
Availability, pack size, lead time, and pricing are confirmed through RFQ.
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