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Home/Compounds/CAS 57381-26-7
Formula C9H7Cl2N5MW 256.09Research-use catalog entryCOA/SDS by request

Irsogladine

CAS Number: 57381-26-7

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Loading RDKit molecule structure...
InChIKey: ATCGGEJZONJOCL-UHFFFAOYSA-NC9H7Cl2N5 | MW 256.09

Chemical Absolute Identifiers

CAS Number

57381-26-7

PubChem CID

3752

Molecular Formula

C9H7Cl2N5

Molecular Weight

256.09 g/mol

Exact Mass

255.007851

InChIKey

ATCGGEJZONJOCL-UHFFFAOYSA-N

IUPAC Name

6-(2,5-dichlorophenyl)-1,3,5-triazine-2,4-diamine

SMILES String

C1=CC(=C(C=C1Cl)C2=NC(=NC(=N2)N)N)Cl

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Irsogladine (CAS 57381-26-7) is listed in the Advanced Chemicals portfolio, with molecular formula C9H7Cl2N5 and molecular weight 256. 09 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: 5-hydroxytryptamine receptor 2B (Homo sapiens) — 2 assays; Transthyretin (Homo sapiens) — 4 assays; Nuclear receptor subfamily 1 group I member 2 (Homo sapiens) — 3 assays; 5-hydroxytryptamine receptor 2A (Homo sapiens) — 2 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

5-hydroxytryptamine receptor 2B

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.66

Experimental evidence source: ChEMBL

Transthyretin

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Nuclear receptor subfamily 1 group I member 2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2A

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

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Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, hydrogen chloride, nitrogen oxides.

Disposal

  • Waste product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
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Fire Fighting

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Accidental Release

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For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Irsogladine

Names & Synonyms

IrsogladinaIrsogladinumDCPDAT6-(2,5-dichlorophenyl)-2,4-diamino-1,3,5-triazinedicloguamine
Show all synonyms
Irsogladine [INN]1,3,5-Triazine-2,4-diamine, 6-(2,5-dichlorophenyl)-2,4-Diamino-6-(2,5-dichlorophenyl)-1,3,5-triazine2,4-Diamino-6-(2,5-dichlorophenyl)-s-triazineIrsogladine (INN)Irsogladine, Irsogladine maleateIrsogladinum [Latin]2',5'-dichlorobenzoguanamineIrsogladina [Spanish]IRSOGLADINE [MI]IRSOGLADINE [WHO-DD]cid_5282435s1929
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID8043999CHEMBL ID: CHEMBL136497CHEBI ID: CHEBI:93307UNII: QBX79NZC1DDRUGBANK ID: DB13056HMDB ID: HMDB0253587KEGG ID: D08087METABOLOMICS WORKBENCH ID: 153928NCI THESAURUS CODE: C65964WIKIDATA ID: Q15634081Pharmakon1600-01502352
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.1021/acs.jmedchem.1c00823Repositioning of the Anthelmintic Drugs Bithionol and Triclabendazole as Transthyretin Amyloidogenesis Inhibitors.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsPMID 34547896Repositioning of the Anthelmintic Drugs Bithionol and Triclabendazole as Transthyretin Amyloidogenesis Inhibitors.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

1,3,5-Triazine-2,4-diamine, 6-(2,5-dichlorophenyl)-, (2Z)-2-butenedioate (1:1)CAS 84504-69-8
BenzoguanamineCAS 91-76-9
1,3,5-Triazine-2,4-diamine, 6-chloro-CAS 3397-62-4
4,6-Diphenyl-1,3,5-triazin-2-amineCAS 5418-07-5
2,4-Diamino-6-(3-(trifluoromethyl)phenyl)-1,3,5-triazineCAS 30508-78-2

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 84504-69-81,3,5-Triazine-2,4-diamine, 6-(2,5-dichlorophenyl)-, (2Z)-2-butenedioate (1:1)CAS 13710-19-5Tolfenamic AcidCAS 102767-28-2LevetiracetamCAS 106308-44-5RufinamideCAS 389-08-2Nalidixic AcidCAS 58-14-0PyrimethamineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 57381-26-7

What are the key identifiers for Irsogladine (CAS 57381-26-7)?

Irsogladine is identified by CAS 57381-26-7, with molecular formula C9H7Cl2N5, molecular weight 256.09, InChIKey ATCGGEJZONJOCL-UHFFFAOYSA-N.

Does CAS 57381-26-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with 5-hydroxytryptamine receptor 2B, Transthyretin, Nuclear receptor subfamily 1 group I member 2, 5-hydroxytryptamine receptor 2A, Alpha-1A adrenergic receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 57381-26-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Irsogladine?

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Is CAS 57381-26-7 available for quotation?

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