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Home/Compounds/CAS 57852-57-0
Formula C26H28ClNO9MW 534Research-use catalog entryCOA/SDS by request

Idarubicin Hydrochloride

CAS Number: 57852-57-0

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Purity
99%
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Loading RDKit molecule structure...
InChIKey: JVHPTYWUBOQMBP-RVFAQHLVSA-NC26H28ClNO9 | MW 534

Chemical Absolute Identifiers

CAS Number

57852-57-0

PubChem CID

636362

Molecular Formula

C26H28ClNO9

Molecular Weight

534 g/mol

Exact Mass

533.145259

InChIKey

JVHPTYWUBOQMBP-RVFAQHLVSA-N

IUPAC Name

(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride

SMILES String

C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O.Cl

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Idarubicin Hydrochloride (CAS 57852-57-0) is listed in the Advanced Chemicals portfolio, with molecular formula C26H28ClNO9 and molecular weight 534. 00 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Rap guanine nucleotide exchange factor 3 (Homo sapiens) — 2 assays; Rap guanine nucleotide exchange factor 4 (Homo sapiens) — 2 assays; Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Rap guanine nucleotide exchange factor 3

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Rap guanine nucleotide exchange factor 4

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Tyrosyl-DNA phosphodiesterase 1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Idarubicin Hydrochloride

Names & Synonyms

Idarubicin HclIdamycinIdamycin PFSIMI 30Idarubicin hydrochloride PFS
Show all synonyms
Hydrochloride, IdarubicinIMI30(2S,4S)-2-Acetyl-4-(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyloxy)-2,5,12-trihydroxy-1,2,3,4-tetrahydrotetracene-6,11-dione monohydrochlorideIdarubicin (hydrochloride)4-Demethoxydaunorubicin hydrochloride(7S,9S)-9-acetyl-7-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,9,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochlorideIdamycin (TN)Idarubicin hydrochloride [USAN:USP:INN]Idarubicin hydrochloride?C26H28ClNO9IDARUBICIN HYDROCHLORIDE [MI]s1228Idarubicin hydrochloride (JP18/USP)IDARUBICIN HYDROCHLORIDE [JAN]Idarubicin (hydrochloride) (Standard)
External Identifiers
EC NUMBER: 260-990-7DSSTOX SUBSTANCE ID: DTXSID0047797CHEMBL ID: CHEMBL1200976CHEBI ID: CHEBI:31686UNII: 5VV3MDU5IEKEGG ID: D01747NCI THESAURUS CODE: C1587RXCUI: 82124WIKIDATA ID: Q27262943
Literature & Patent References
DOI 10.1016/j.ejmech.2024.116948Sensitive quantification of fibroblast activation protein and high-throughput screening for inhibition by FDA-approved compounds.PMID 39437576Sensitive quantification of fibroblast activation protein and high-throughput screening for inhibition by FDA-approved compounds.DOI 10.1016/j.bmc.2023.117383Identification of small-molecule inhibitors of human MUS81-EME1/2 by FRET-based high-throughput screening.DOI 10.6019/EOS300108ECBD screening data for assay EOS300108PMID 37352577Identification of small-molecule inhibitors of human MUS81-EME1/2 by FRET-based high-throughput screening.DOI 10.6019/EOS300033ECBD screening data for assay EOS300033DOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Epirubicin HydrochlorideCAS 56390-09-1
ValrubicinCAS 56124-62-0

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 56390-09-1Epirubicin HydrochlorideCAS 56124-62-0ValrubicinCAS 5407-46-52,6,7-Trihydroxy-9-methyl-3H-xanthen-3-oneCAS 57597-64-57-(Diethylamino)-2-oxo-2H-chromene-3-carbaldehydeCAS 119413-54-6Topotecan HydrochlorideCAS 117467-28-4Cefditoren PivoxilCAS 3599-32-4Indocyanine GreenCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 57852-57-0

What are the key identifiers for Idarubicin Hydrochloride (CAS 57852-57-0)?

Idarubicin Hydrochloride is identified by CAS 57852-57-0, with molecular formula C26H28ClNO9, molecular weight 534, InChIKey JVHPTYWUBOQMBP-RVFAQHLVSA-N.

Does CAS 57852-57-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Rap guanine nucleotide exchange factor 3, Rap guanine nucleotide exchange factor 4, Tyrosyl-DNA phosphodiesterase 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 57852-57-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Idarubicin Hydrochloride?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 57852-57-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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