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Home/Compounds/CAS 59-67-6
Formula C6H5NO2MW 123.11Research-use catalog entryCOA/SDS by request

Nicotinic Acid

CAS Number: 59-67-6

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1 kg
Purity
98%
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Loading RDKit molecule structure...
InChIKey: PVNIIMVLHYAWGP-UHFFFAOYSA-NC6H5NO2 | MW 123.11

Chemical Absolute Identifiers

CAS Number

59-67-6

PubChem CID

938

Molecular Formula

C6H5NO2

Molecular Weight

123.11 g/mol

Exact Mass

123.032028

InChIKey

PVNIIMVLHYAWGP-UHFFFAOYSA-N

IUPAC Name

pyridine-3-carboxylic acid

SMILES String

C1=CC(=CN=C1)C(=O)O

Physical Properties

Appearance

Nicotinic acid is an odorless white crystalline powder with a feebly acid taste. pH (saturated aqueous solution) 2.7. pH (1.3% solution) 3-3.5. (NTP, 1992)

Flash Point

193.0 °C

Show more physical data

Vapor Pressure

Estimated very low; unit not specified

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Nicotinic Acid (CAS 59-67-6) is listed in the Advanced Chemicals portfolio, with molecular formula C6H5NO2 and molecular weight 123. 11 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Natural Product ResearchSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Hydroxycarboxylic acid receptor 2 (Homo sapiens) — 56 assays; Hydroxycarboxylic acid receptor 2 (Mus musculus) — 6 assays; Hydroxycarboxylic acid receptor 2 (Rattus norvegicus) — 4 assays; Lysosomal alpha-glucosidase (Homo sapiens) — 2 assays; Amyloid-beta precursor protein (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Hydroxycarboxylic acid receptor 2

Homo sapiens · SINGLE PROTEIN · 56 qualifying assays · 28 documents · best pChEMBL 8.06

Experimental evidence source: ChEMBL

Hydroxycarboxylic acid receptor 2

Mus musculus · SINGLE PROTEIN · 6 qualifying assays · 5 documents · best pChEMBL 7.54

Experimental evidence source: ChEMBL

Hydroxycarboxylic acid receptor 2

Rattus norvegicus · SINGLE PROTEIN · 4 qualifying assays · 4 documents · best pChEMBL 7.48

Experimental evidence source: ChEMBL

Lysosomal alpha-glucosidase

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.45

Experimental evidence source: ChEMBL

Amyloid-beta precursor protein

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.88

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Nicotinic Acid

Names & Synonyms

niacin3-pyridinecarboxylic acid3-Carboxypyridinevitamin B3wampocap
Show all synonyms
ApelagrinPellagrinAkotinDaskilEfacinNiaspanPeloninLinicnicolarNicotinipcaNicacidNicanginNiconacidNyclin
External Identifiers
EC NUMBER: 200-441-0DSSTOX SUBSTANCE ID: DTXSID1020932CHEMBL ID: CHEMBL573CHEBI ID: CHEBI:15940UNII: 2679MF687ADRUGBANK ID: DB00627HMDB ID: HMDB0001488ICSC NUMBER: 1702KEGG ID: C00253KEGG ID: D00049METABOLOMICS WORKBENCH ID: 37821NCI THESAURUS CODE: C689PHARMGKB ID: PA450617RXCUI: 7393
Experimental Spectrum References
13C NMR Spectra15N NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR SpectraRaman Spectra — Forensic Spectral ResearchUV-VIS SpectraVapor Phase IR Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2025.117280Progress in the development of macrophage migration inhibitory factor small-molecule inhibitors.DOI 10.1021/acs.jmedchem.5c00056Substrate Specificity of the Organic Cation Transporters MATE1 and MATE2K and Functional Overlap with OCT1 and OCT2.DOI 10.1021/acs.jmedchem.5c004183,5-Dihydroxybenzoic Acid as a Potent Inhibitor of Tyrosine Phenol-Lyase Decreases Fecal Phenol Levels in Mice.DOI 10.1021/acs.jnatprod.5c00086Niacin Ester Derivative of Brefeldin A as a Potential Dual-Target Arf1/BMX Inhibitor for Bladder Cancer.PMID 39854942Progress in the development of macrophage migration inhibitory factor small-molecule inhibitors.PMID 40085024Niacin Ester Derivative of Brefeldin A as a Potential Dual-Target Arf1/BMX Inhibitor for Bladder Cancer.PMID 401731063,5-Dihydroxybenzoic Acid as a Potent Inhibitor of Tyrosine Phenol-Lyase Decreases Fecal Phenol Levels in Mice.PMID 40512599Substrate Specificity of the Organic Cation Transporters MATE1 and MATE2K and Functional Overlap with OCT1 and OCT2.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

3-Hydroxypicolinic AcidCAS 874-24-8
2,6-Dimethoxybenzoic AcidCAS 1466-76-8
pyridine-4-carboximidothioic acidCAS 2196-13-6
TrigonellineCAS 535-83-1
p-Aminohippuric acidCAS 61-78-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 13710-19-5Tolfenamic AcidCAS 138402-11-6IrbesartanCAS 169590-42-5CelecoxibCAS 320-67-2AzacytidineCAS 76824-35-6FamotidineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 59-67-6

What are the key identifiers for Nicotinic Acid (CAS 59-67-6)?

Nicotinic Acid is identified by CAS 59-67-6, with molecular formula C6H5NO2, molecular weight 123.11, InChIKey PVNIIMVLHYAWGP-UHFFFAOYSA-N.

Does CAS 59-67-6 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Hydroxycarboxylic acid receptor 2, Hydroxycarboxylic acid receptor 2, Hydroxycarboxylic acid receptor 2, Lysosomal alpha-glucosidase, Amyloid-beta precursor protein. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 59-67-6?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Nicotinic Acid?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 59-67-6 available for quotation?

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