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Home/Compounds/CAS 60-18-4
Formula C9H11NO3MW 181.19Research-use catalog entryCOA/SDS by request

L-Tyrosine

CAS Number: 60-18-4

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Loading RDKit molecule structure...
InChIKey: OUYCCCASQSFEME-QMMMGPOBSA-NC9H11NO3 | MW 181.19

Chemical Absolute Identifiers

CAS Number

60-18-4

PubChem CID

6057

Molecular Formula

C9H11NO3

Molecular Weight

181.19 g/mol

Exact Mass

181.073893

InChIKey

OUYCCCASQSFEME-QMMMGPOBSA-N

IUPAC Name

(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid

SMILES String

C1=CC(=CC=C1C[C@@H](C(=O)O)N)O

Physical Properties

Melting Point

343–344 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

L-Tyrosine (CAS 60-18-4) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C9H11NO3 and molecular weight 181. 19 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Large neutral amino acids transporter small subunit 1 (Homo sapiens) — 7 assays; Carbonic anhydrase 2 (Homo sapiens) — 15 assays; Carbonic anhydrase 1 (Homo sapiens) — 13 assays; Tyrosinase (Agaricus bisporus) — 4 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Large neutral amino acids transporter small subunit 1

Homo sapiens · SINGLE PROTEIN · 7 qualifying assays · 3 documents · best pChEMBL 4.17

Experimental evidence source: ChEMBL

Carbonic anhydrase 2

Homo sapiens · SINGLE PROTEIN · 15 qualifying assays · 13 documents

Experimental evidence source: ChEMBL

Carbonic anhydrase 1

Homo sapiens · SINGLE PROTEIN · 13 qualifying assays · 11 documents

Experimental evidence source: ChEMBL

Tyrosinase

Agaricus bisporus · SINGLE PROTEIN · 4 qualifying assays · 2 documents

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • Waste product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

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  • Use personal protective equipment and emergency procedures.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

L-Tyrosine

Names & Synonyms

tyrosine(S)-Tyrosinep-TyrosineL-p-Tyrosine4-Hydroxy-L-phenylalanine
Show all synonyms
tirosinaTyrosinumL-Phenylalanine, 4-hydroxy-beta-(p-Hydroxyphenyl)alanine(-)-alpha-Amino-p-hydroxyhydrocinnamic acidFEMA No. 3736(S)-alpha-Amino-4-hydroxybenzenepropanoic acid(S)-(-)-Tyrosine(S)-3-(p-Hydroxyphenyl)alanineL-TyrosinL-Tyr(S)-2-Amino-3-(p-hydroxyphenyl)propionic acid2-Amino-3-(4-hydroxyphenyl)propanoic acid, (S)-3-(p-Hydroxyphenyl)alanine
External Identifiers
EC NUMBER: 200-460-4DSSTOX SUBSTANCE ID: DTXSID1023730CHEMBL ID: CHEMBL925CHEBI ID: CHEBI:17895UNII: 42HK56048UDRUGBANK ID: DB00135HMDB ID: HMDB0000158KEGG ID: C00082KEGG ID: D00022METABOLOMICS WORKBENCH ID: 37107NCI THESAURUS CODE: C915PHARMGKB ID: PA451822RXCUI: 10962
Experimental Spectrum References
13C NMR Spectra1H NMR SpectraATR-IR Spectra — Bio-Rad Laboratories, Inc.FTIR SpectraIR SpectraRaman Spectra — Bio-Rad Laboratories, Inc.UV SpectraUV-VIS Spectra
Literature & Patent References
DOI 10.1021/acs.jnatprod.4c01008Purified <i>Monascus</i> Pigments: Biological Activities and Mechanisms of Action.PMID 39906945Purified <i>Monascus</i> Pigments: Biological Activities and Mechanisms of Action.DOI 10.1016/j.ejmech.2023.115672Catechol-mimicking transition-state analogues as non-oxidizable inhibitors of tyrosinases.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37487307Catechol-mimicking transition-state analogues as non-oxidizable inhibitors of tyrosinases.DOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

O-benzyl-L-tyrosineCAS 16652-64-5
(2S)-2-Ethoxy-3-(4-hydroxyphenyl)propanoic acidCAS 325793-65-5
Ethyl 2-ethoxy-3-(4-hydroxyphenyl)propanoateCAS 197299-16-4
D-SerineCAS 312-84-5
(S)-3-(4-(benzyloxy)phenyl)-2-hydroxypropanoic acidCAS 162919-37-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 16652-64-5O-benzyl-L-tyrosineCAS 325793-65-5(2S)-2-Ethoxy-3-(4-hydroxyphenyl)propanoic acidCAS 197299-16-4Ethyl 2-ethoxy-3-(4-hydroxyphenyl)propanoateCAS 63-91-2L-PhenylalanineCAS 181695-72-7ValdecoxibCAS 73-22-3L-TryptophanCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 60-18-4

What are the key identifiers for L-Tyrosine (CAS 60-18-4)?

L-Tyrosine is identified by CAS 60-18-4, with molecular formula C9H11NO3, molecular weight 181.19, InChIKey OUYCCCASQSFEME-QMMMGPOBSA-N.

Does CAS 60-18-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Large neutral amino acids transporter small subunit 1, Carbonic anhydrase 2, Carbonic anhydrase 1, Tyrosinase, Alpha-1A adrenergic receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 60-18-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for L-Tyrosine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 60-18-4 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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