Preliminary reference disclaimer
This preliminary safety reference is generated from structured MolGraph catalog fields and public reference-style data. It is not a supplier-issued Safety Data Sheet and should not be used as a substitute for supplier-issued documentation, workplace safety review, transport classification, or regulatory compliance decisions. For supplier SDS or COA, submit a documentation request through MolGraph.
Identity
CAS Number
606144-04-1
Chemical name
AZ-133266637
Molecular formula
C15H10BrClFN3O2
Molecular weight
398.61 g/mol
Synonyms
D67NVR9LE7; 5-((4-Bromo-2-chlorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylic acid; 5-(4-bromo-2-chlorophenylamino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylic acid; C15H10BrClFN3O2; Selumetinib metabolite M15; 6-(4-bromo-2-chlorophenylamino)-7-fluoro-3-methyl-3H-benzo[d]imidazole-5-carboxylic acid; 1H-Benzimidazole-6-carboxylic acid, 5-((4-bromo-2-chlorophenyl)amino)-4-fluoro-1-methyl-; 5-((4-Bromo-2-chlorophenyl)amino)-4-fluoro-1-methyl-1H-benzimidazole-6-carboxylic acid; 6-(4-Bromo-2-chlorophenylamino)-7-fluoro-3-methyl-3H-benzo(d)imidazole-5-carboxylic acid; 6-(4-Bromo-2-chlorophenylamino)-7-fluoro-3-methyl-benzimidazole-5-carboxylic acid; UNII-D67NVR9LE7; XAAPQRFIXGDKPZ-UHFFFAOYSA-N
InChIKey
XAAPQRFIXGDKPZ-UHFFFAOYSA-N
PubChem CID
16092137
Hazard / GHS Reference
GHS Pictograms
GHS07
Catalog reference cue; confirm supplier documentation before use.
Handling & PPE
- Handle in a well-ventilated area or fume hood.
- Avoid inhalation, ingestion, and skin/eye contact.
- Keep container tightly closed in a dry, cool, and well-ventilated place.
- Store away from incompatible materials.
- Wash thoroughly after handling.
- Use appropriate PPE such as lab coat, compatible gloves, and eye protection.
- Wear chemical-resistant gloves (e.g., nitrile, neoprene) suitable for the task.
- Wear safety glasses or chemical splash goggles.
- Use respiratory protection if ventilation is inadequate or if there is a risk of dust/aerosol exposure.
First Aid / Accidental Release
- In case of inhalation, move to fresh air. If not breathing, give artificial respiration. Seek medical attention.
- In case of skin contact, wash immediately with plenty of soap and water. Remove contaminated clothing and shoes. Seek medical attention if irritation persists.
- In case of eye contact, rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Seek medical attention.
- In case of ingestion, rinse mouth with water. Do NOT induce vomiting. Seek medical attention.
- Always seek medical attention according to institutional procedures for any significant exposure.
- For spills, avoid dust or aerosol generation and collect using trained-lab procedures.
- Contain any spills to prevent material from entering drains or watercourses.
- Absorb liquid spills with inert material (e.g., sand, vermiculite) and place in suitable containers for disposal.
- Ensure adequate ventilation during cleanup.
Firefighting / Stability
- Use extinguishing media appropriate for the surrounding fire and material.
- Wear self-contained breathing apparatus (SCBA) and full protective gear for fire fighting.
- Keep containers cool with water spray if exposed to fire.
- Avoid inhalation of combustion products.
- Move containers from fire area if it can be done without risk.
- This material is considered stable under recommended storage conditions.
- Avoid strong oxidizing agents, strong acids, and strong bases.
- Avoid conditions such as heat, flames, sparks, and incompatible materials.
- Hazardous decomposition products may include carbon oxides, nitrogen oxides, hydrogen halides, and bromine/chlorine compounds.
Physical and Chemical Reference
Appearance
White to off-white solid
Catalog reference value; verify against supplier SDS before use.
Physical State
Solid
Catalog reference value; verify against supplier SDS before use.
Melting Point
205.0 °C
Catalog reference value; verify against supplier SDS before use.
Boiling Point
470.0 °C
Catalog reference value; verify against supplier SDS before use.
Density
1.72 g/cm³
Catalog reference value; verify against supplier SDS before use.
Water Solubility
Slightly soluble
Catalog reference value; verify against supplier SDS before use.
Flash Point
306.1 °C
Catalog reference value; verify against supplier SDS before use.
Vapor Pressure
Estimated very low; unit not specified
Catalog reference value; verify against supplier SDS before use.
Autoignition Temp
475.0 °C
Catalog reference value; verify against supplier SDS before use.
Transport / Shipment Review
HS6
293399
Preliminary catalog cue; verify before compliance decisions.
HS Code
293399
Source: catalog inference.
GHS Pictograms
GHS07
Preliminary catalog cue; verify before compliance decisions.
Compliance
standard-ruo
Preliminary catalog cue; verify before compliance decisions.
Registration Status
DSL: pending; AICS: pending; ENCS: pending; ICSR: pending; TSCA: pending; IECSC: pending; INSQR: pending; REACH: pending; K-REACH: pending; SEA_Regulatory: pending
Registration values are catalog reference status cues and may require jurisdiction-specific review.
Shipment review
Shipment details require review before fulfillment.
Preliminary catalog cue; verify before compliance decisions.
- Transport classification must be confirmed using supplier SDS and shipment documentation before dispatch.