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Home/Compounds/CAS 60940-34-3
Formula C13H9NOSeMW 274.19Research-use catalog entryCOA/SDS by request

Ebselen

CAS Number: 60940-34-3

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Loading RDKit molecule structure...
InChIKey: DYEFUKCXAQOFHX-UHFFFAOYSA-NC13H9NOSe | MW 274.19

Chemical Absolute Identifiers

CAS Number

60940-34-3

PubChem CID

3194

Molecular Formula

C13H9NOSe

Molecular Weight

274.19 g/mol

Exact Mass

274.98494

InChIKey

DYEFUKCXAQOFHX-UHFFFAOYSA-N

IUPAC Name

2-phenyl-1,2-benzoselenazol-3-one

SMILES String

C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Ebselen (CAS 60940-34-3) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C13H9NOSe and molecular weight 274. 19 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Toxin B (Clostridioides difficile) — 2 assays; Replicase polyprotein 1ab (Severe acute respiratory syndrome coronavirus 2) — 35 assays; Insulin-degrading enzyme (Homo sapiens) — 8 assays; Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens) — 3 assays; Metallo-beta-lactamase type 2 (Bacteria) — 6 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Toxin B

Clostridioides difficile · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 8.16

Experimental evidence source: ChEMBL

Replicase polyprotein 1ab

Severe acute respiratory syndrome coronavirus 2 · SINGLE PROTEIN · 35 qualifying assays · 24 documents · best pChEMBL 8

Experimental evidence source: ChEMBL

Insulin-degrading enzyme

Homo sapiens · SINGLE PROTEIN · 8 qualifying assays · 1 documents · best pChEMBL 7.85

Experimental evidence source: ChEMBL

Tyrosyl-DNA phosphodiesterase 1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 7.75

Experimental evidence source: ChEMBL

Metallo-beta-lactamase type 2

Bacteria · SINGLE PROTEIN · 6 qualifying assays · 4 documents · best pChEMBL 7.14

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Ebselen

Names & Synonyms

2-Phenyl-1,2-benzisoselenazol-3(2H)-oneEbseleneEbselenoEbselenumPZ 51
Show all synonyms
2-phenyl-1,2-benzoisoselenazol-3(2H)-one2-phenyl-2,3-dihydro-1,2-benzoselenazol-3-oneSPI 10052-phenylbenzoisoselenazol-3(2H)-one2-phenylbenzo[d][1,2]selenazol-3(2H)-oneEbselen [INN]Ebselene [French]Ebselenum [Latin]HarmokisaneEbseleno [Spanish]C13H9NOSePZ51CCRIS 3714
External Identifiers
EC NUMBER: 612-054-8DSSTOX SUBSTANCE ID: DTXSID7045150CHEMBL ID: CHEMBL51085CHEBI ID: CHEBI:77543UNII: 40X2P7DPGHDRUGBANK ID: DB12610METABOLOMICS WORKBENCH ID: 153566NCI THESAURUS CODE: C65503PHARMGKB ID: PA161660841WIKIDATA ID: Q5332073PZ-51
Literature & Patent References
DOI 10.1016/j.ejmech.2025.117243Development of molecular Trojan horses targeting New Delhi metallo-β-lactamase-1 for the restoration of meropenem susceptibility in drug-resistant bacteria.DOI 10.1016/j.ejmech.2025.117359Synthesis and evaluation of novel ebselen derivatives as urease inhibitors for combating Helicobacter pylori infections.DOI 10.1016/j.ejmech.2025.117479Cross-subclass metallo-β-lactamase inhibitors: From structural and catalytic commonalities guiding design.DOI 10.1016/j.ejmech.2025.117509Development of acylhydrazone linked thiazoles as non-covalent dual inhibitors of SARS-CoV-2 proteases.DOI 10.1016/j.ejmech.2025.117571Optimized ebselen derivatives as novel potent Escherichia coli β-glucuronidase covalent allosteric inhibitors.DOI 10.1021/acsmedchemlett.5c00057Halogenated <i>N</i>-Benzylbenzisoselenazolones Efficiently Inhibit <i>Helicobacter pylori</i> Ureolysis <i>In Vitro</i>.PMID 39798399Development of molecular Trojan horses targeting New Delhi metallo-β-lactamase-1 for the restoration of meropenem susceptibility in drug-resistant bacteria.PMID 39919439Synthesis and evaluation of novel ebselen derivatives as urease inhibitors for combating Helicobacter pylori infections.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

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RFQ questions for CAS 60940-34-3

What are the key identifiers for Ebselen (CAS 60940-34-3)?

Ebselen is identified by CAS 60940-34-3, with molecular formula C13H9NOSe, molecular weight 274.19, InChIKey DYEFUKCXAQOFHX-UHFFFAOYSA-N.

Does CAS 60940-34-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Toxin B, Replicase polyprotein 1ab, Insulin-degrading enzyme, Tyrosyl-DNA phosphodiesterase 1, Metallo-beta-lactamase type 2. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 60940-34-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Ebselen?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 60940-34-3 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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