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Home/Compounds/CAS 61-90-5
Formula C6H13NO2MW 131.17Research-use catalog entryCOA/SDS by request

L-Leucine

CAS Number: 61-90-5

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Loading RDKit molecule structure...
InChIKey: ROHFNLRQFUQHCH-YFKPBYRVSA-NC6H13NO2 | MW 131.17

Chemical Absolute Identifiers

CAS Number

61-90-5

PubChem CID

6106

Molecular Formula

C6H13NO2

Molecular Weight

131.17 g/mol

Exact Mass

131.094629

InChIKey

ROHFNLRQFUQHCH-YFKPBYRVSA-N

IUPAC Name

(2S)-2-amino-4-methylpentanoic acid

SMILES String

CC(C)C[C@@H](C(=O)O)N

Physical Properties

Melting Point

293.0 °C

Density

1.29 g/cm³

Show more physical data

Vapor Pressure

Estimated very low; unit not specified

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

L-Leucine (CAS 61-90-5) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C6H13NO2 and molecular weight 131. 17 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Large neutral amino acids transporter small subunit 1 (Homo sapiens) — 8 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Large neutral amino acids transporter small subunit 1

Homo sapiens · SINGLE PROTEIN · 8 qualifying assays · 3 documents · best pChEMBL 4.07

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

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Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

L-Leucine

Names & Synonyms

leucine(S)-Leucine(S)-2-Amino-4-methylpentanoic acid(S)-(+)-LeucineLeucin
Show all synonyms
(S)-2-Amino-4-methylvaleric acidL-alpha-Aminoisocaproic acidLEUCINE, L-LeucinumLeucinaFEMA No. 3297(2S)-alpha-leucineL-leucin2-amino-4-methylvaleric acidL-(-)-2-Amino-4-methylpentanoic acidalpha-Aminoisocaproic acidL-LeuzinLeucine, l(2S)-alpha-2-amino-4-methylvaleric acid
External Identifiers
EC NUMBER: 200-522-0DSSTOX SUBSTANCE ID: DTXSID9023203CHEMBL ID: CHEMBL291962CHEBI ID: CHEBI:15603UNII: GMW67QNF9CDRUGBANK ID: DB00149HMDB ID: HMDB0000687KEGG ID: C00123KEGG ID: D00030METABOLOMICS WORKBENCH ID: 42493NCI THESAURUS CODE: C29599PHARMGKB ID: PA450197RXCUI: 6308
Experimental Spectrum References
13C NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR Spectra — Bio-Rad Laboratories, Inc.Raman Spectra — Bio-Rad Laboratories, Inc.
Literature & Patent References
DOI 10.1021/acs.jmedchem.3c02245Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator.PMID 38470246Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortDOI 10.1021/acs.jmedchem.8b01007Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1).

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

(S)-2-bromo-4-methylpentanoic acidCAS 28659-87-2
Isobutylglutaric acidCAS 75143-89-4
Pentanoyl chloride, 4-methyl-CAS 38136-29-7
Diethyl (1-cyano-3-methylbutyl)malonateCAS 186038-82-4
(S)-3-Cyano-5-methylhexanoic acid ethyl esterCAS 181289-39-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 28659-87-2(S)-2-bromo-4-methylpentanoic acidCAS 75143-89-4Isobutylglutaric acidCAS 60-18-4L-TyrosineCAS 63-68-3L-MethionineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 61-90-5

What are the key identifiers for L-Leucine (CAS 61-90-5)?

L-Leucine is identified by CAS 61-90-5, with molecular formula C6H13NO2, molecular weight 131.17, InChIKey ROHFNLRQFUQHCH-YFKPBYRVSA-N.

Does CAS 61-90-5 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Large neutral amino acids transporter small subunit 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 61-90-5?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for L-Leucine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 61-90-5 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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