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Home/Compounds/CAS 622-52-6
Formula C8H10N2SMW 166.25Research-use catalog entryCOA/SDS by request

p-Tolylthiourea

CAS Number: 622-52-6

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Loading RDKit molecule structure...
InChIKey: VXLFMCZPFIKKDZ-UHFFFAOYSA-NC8H10N2S | MW 166.25

Chemical Absolute Identifiers

CAS Number

622-52-6

PubChem CID

722833

Molecular Formula

C8H10N2S

Molecular Weight

166.25 g/mol

Exact Mass

166.05647

InChIKey

VXLFMCZPFIKKDZ-UHFFFAOYSA-N

IUPAC Name

(4-methylphenyl)thiourea

SMILES String

CC1=CC=C(C=C1)NC(=S)N

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

p-Tolylthiourea (CAS 622-52-6) is listed in the Advanced Chemicals portfolio, with molecular formula C8H10N2S and molecular weight 166. 25 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Organic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Tyrosinase (Agaricus bisporus) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Tyrosinase

Agaricus bisporus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.85

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

p-Tolylthiourea

Names & Synonyms

1-(p-Tolyl)thiourea1-p-Tolylthiourea4-MethylphenylthioureaN-(4-Methylphenyl)thiourea1-(4-Methylphenyl)-2-thiourea
Show all synonyms
Urea, 2-thio-1-p-tolyl-N-p-TolylthioureaThiourea, (4-methylphenyl)-p-Tolylthiocarbamide4-Tolylthiourea1-(4-methylphenyl)thiourea(p-Methylphenyl)thioureaThiourea, N-(4-methylphenyl)-1-(4-methylphenyl) thioureaN-(p-Tolyl)thioureaamino[(4-methylphenyl)amino]methane-1-thionep-Tolythioureap-tolyl thioureap-Tolyl-isothioharnstoff
External Identifiers
EC NUMBER: 210-740-8DSSTOX SUBSTANCE ID: DTXSID40211239CHEMBL ID: CHEMBL1088360UNII: SL946R8H7JWIKIDATA ID: Q72495430
Experimental Spectrum References
13C NMR SpectraATR-IR Spectra — Bio-Rad Laboratories, Inc.FTIR SpectraRaman Spectra — Bio-Rad Laboratories, Inc.UV-VIS Spectra
Literature & Patent References
DOI 10.1016/j.bmcl.2011.09.024Structural requirement of phenylthiourea analogs for their inhibitory activity of melanogenesis and tyrosinase.PMID 21978680Structural requirement of phenylthiourea analogs for their inhibitory activity of melanogenesis and tyrosinase.DOI 10.1016/j.bmcl.2010.02.067Structural requirement(s) of N-phenylthioureas and benzaldehyde thiosemicarbazones as inhibitors of melanogenesis in melanoma B 16 cells.PMID 20359890Structural requirement(s) of N-phenylthioureas and benzaldehyde thiosemicarbazones as inhibitors of melanogenesis in melanoma B 16 cells.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

N,N''-1,4-Phenylenebis(thiourea)CAS 1519-70-6
1-(4-Aminophenyl)thioureaCAS 3394-08-9
3-Amino-1-(4-methylphenyl)thioureaCAS 13278-67-6
N-(4-Thioureido-phenyl)-acetamideCAS 1614-33-1
4-FluorophenylthioureaCAS 459-05-2

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1519-70-6N,N''-1,4-Phenylenebis(thiourea)CAS 3394-08-91-(4-Aminophenyl)thioureaCAS 13278-67-63-Amino-1-(4-methylphenyl)thioureaCAS 1614-33-1N-(4-Thioureido-phenyl)-acetamideCAS 459-05-24-FluorophenylthioureaCAS 102-08-9DiphenylthioureaCAS 103-85-5PhenylthioureaCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 622-52-6

What are the key identifiers for p-Tolylthiourea (CAS 622-52-6)?

p-Tolylthiourea is identified by CAS 622-52-6, with molecular formula C8H10N2S, molecular weight 166.25, InChIKey VXLFMCZPFIKKDZ-UHFFFAOYSA-N.

Does CAS 622-52-6 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Tyrosinase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 622-52-6?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for p-Tolylthiourea?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 622-52-6 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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