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Home/Compounds/CAS 64183-27-3
Formula C10H12FN5O3MW 269.23Research-use catalog entryCOA/SDS by request

2'-Fluoro-2'-deoxyadenosine

CAS Number: 64183-27-3

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Loading RDKit molecule structure...
InChIKey: ZGYYPTJWJBEXBC-QYYRPYCUSA-NC10H12FN5O3 | MW 269.23

Chemical Absolute Identifiers

CAS Number

64183-27-3

PubChem CID

100253

Molecular Formula

C10H12FN5O3

Molecular Weight

269.23 g/mol

Exact Mass

269.092417

InChIKey

ZGYYPTJWJBEXBC-QYYRPYCUSA-N

IUPAC Name

(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol

SMILES String

C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)F)N

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

2'-Fluoro-2'-deoxyadenosine (CAS 64183-27-3) is listed in the Advanced Chemicals portfolio, with molecular formula C10H12FN5O3 and molecular weight 269. 23 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: RNA-directed RNA polymerase (Hepacivirus hominis) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

RNA-directed RNA polymerase

Hepacivirus hominis · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

2'-Fluoro-2'-deoxyadenosine

Names & Synonyms

2'-Deoxy-2'-fluoroadenosine5'-FDAAdenosine, 2'-deoxy-2'-fluoro-(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol2 inverted exclamation marka-Deoxy-2 inverted exclamation marka-fluoroadenosine
Show all synonyms
(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol9-(2-Fluoro-2-deoxy-beta-D-ribofuranosyl)-purin-6-amine2'F-dA2'-F-dA2'-Deoxy-2'-fluoro-D-adenosine2'-Fluoro-2'-deoxy-D-adenosine2'-BETA-FLUORO-2',3'-DEOXYADENOSINE9-(2-Deoxy-2-fluoro-beta-D-ribofuranosyl)adenine9-(2-Fluoro-2-deoxy-?-D-ribofuranosyI)-ad enine6-Amino-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine2 inverted exclamation mark -Deoxy-2 inverted exclamation mark -fluoroadenosine(2R,3R,4R,5R)-4-Fluoro-2-hydroxymethyl-5-(6-methylamino-purin-9-yl)-tetrahydro-furan-3-ol
External Identifiers
EC NUMBER: 814-045-6DSSTOX SUBSTANCE ID: DTXSID60982712CHEMBL ID: CHEMBL309579WIKIDATA ID: Q76009755
Literature & Patent References
DOI 10.1016/j.bmcl.2015.04.073Discovery of β-D-2'-deoxy-2'-α-fluoro-4'-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases.PMID 25978965Discovery of β-D-2'-deoxy-2'-α-fluoro-4'-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases.DOI 10.1016/j.bmcl.2013.03.095Evaluation of 2'-α-fluorine modified nucleoside phosphonates as potential inhibitors of HCV polymerase.PMID 23639543Evaluation of 2'-α-fluorine modified nucleoside phosphonates as potential inhibitors of HCV polymerase.DOI 10.1016/j.bmcl.2012.03.087S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,D-arabinofuranosyl)adenine.PMID 22579483S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,D-arabinofuranosyl)adenine.DOI 10.1021/jm030424eStructure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase.PMID 15084127Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-olCAS 20227-41-2
VidarabineCAS 5536-17-4
9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-, hydrate (1:1)CAS 24356-66-9
ClofarabineCAS 123318-82-1
5'-Deoxy-5'-fluoroadenosineCAS 731-98-6

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 20227-41-2(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-olCAS 5536-17-4VidarabineCAS 24356-66-99H-Purin-6-amine, 9-beta-D-arabinofuranosyl-, hydrate (1:1)CAS 123318-82-1ClofarabineCAS 731-98-65'-Deoxy-5'-fluoroadenosineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 64183-27-3

What are the key identifiers for 2'-Fluoro-2'-deoxyadenosine (CAS 64183-27-3)?

2'-Fluoro-2'-deoxyadenosine is identified by CAS 64183-27-3, with molecular formula C10H12FN5O3, molecular weight 269.23, InChIKey ZGYYPTJWJBEXBC-QYYRPYCUSA-N.

Does CAS 64183-27-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with RNA-directed RNA polymerase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 64183-27-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 2'-Fluoro-2'-deoxyadenosine?

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Is CAS 64183-27-3 available for quotation?

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