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Home/Compounds/CAS 64461-82-1
Formula C9H9Cl2N5SMW 290.17Research-use catalog entryCOA/SDS by request

Tizanidine Hydrochloride

CAS Number: 64461-82-1

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Loading RDKit molecule structure...
InChIKey: ZWUKMNZJRDGCTQ-UHFFFAOYSA-NC9H9Cl2N5S | MW 290.17

Chemical Absolute Identifiers

CAS Number

64461-82-1

PubChem CID

114869

Molecular Formula

C9H9Cl2N5S

Molecular Weight

290.17 g/mol

Exact Mass

288.995572

InChIKey

ZWUKMNZJRDGCTQ-UHFFFAOYSA-N

IUPAC Name

5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine;hydrochloride

SMILES String

C1CN=C(N1)NC2=C(C=CC3=NSN=C32)Cl.Cl

Physical Properties

Water Solubility

43.5 mol/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Tizanidine Hydrochloride (CAS 64461-82-1) is listed in the Inhibitors and Agonists portfolio, with molecular formula C9H9Cl2N5S and molecular weight 290. 17 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for biochemical and pharmacology research workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Bioactivity ScreeningResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Alpha-2A adrenergic receptor (Homo sapiens) — 4 assays; Adhesion G-protein coupled receptor F1 (Homo sapiens) — 3 assays; Apelin receptor (Homo sapiens) — 3 assays; Beta-2 adrenergic receptor (Homo sapiens) — 3 assays; C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Alpha-2A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 2 documents · best pChEMBL 7.48

Experimental evidence source: ChEMBL

Adhesion G-protein coupled receptor F1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Apelin receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Beta-2 adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

C5a anaphylatoxin chemotactic receptor 1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, hydrogen chloride, nitrogen oxides, sulfur oxides.

Disposal

  • Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Tizanidine Hydrochloride

Names & Synonyms

Tizanidine HclDS 103-282AN021Tizanidine (as hydrochloride)ONTRALFY
Show all synonyms
5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole hydrochloride2,1,3-Benzothiadiazol-4-amine, 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-, monohydrochloridetizanidine monohydrochlorideSirdalud MRTIZANDINETizanidne Hydrochloride5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine monohydrochlorideZanaflex5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine hydrochloride5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)benzo[c][1,2,5]thiadiazol-4-amine hydrochlorideTizanidine (hydrochloride)5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole monohydrochlorideC9H9Cl2N5S5-chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazolehydrochlorideTizanidinehydrochloride
External Identifiers
EC NUMBER: 630-412-1DSSTOX SUBSTANCE ID: DTXSID9046990CHEMBL ID: CHEMBL1200329CHEBI ID: CHEBI:9609UNII: B53E3NMY5CKEGG ID: D00776NCI THESAURUS CODE: C47760RXCUI: 236460
Experimental Spectrum References
ATR-IR Spectra — Forensic Spectral ResearchRaman Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.6019/CHEMBL5442687EUbOPEN Chemogenomics Library - GPCR Dose-ResposeDOI 10.6019/CHEMBL5665443Enzyme Inhibitor Single Concentration assay results for EUbOPEN Chemogenomics LibraryDOI 10.6019/CHEMBL5724562Toxicity screen in isolated B cell assay results for EUbOPEN Chemogenomics LibraryDOI 10.6019/CHEMBL5724581Toxicity screen in purified B cell assay results for EUbOPEN Chemogenomics LibraryDOI 10.6019/CHEMBL5724801EUbOPEN Chemogenomics Library - MultiplexDOI 10.6019/CHEMBL5209801GPCR results for EUbOPEN Chemogenomics Library 3DOI 10.6019/CHEMBL5303300EUbOPEN Chemogenomics Library - MultiplexDOI 10.6019/CHEMBL5058564Tm Shift (DSF) assay results for EUbOPEN Chemogenomis Library 2 (Incucyte)

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

(+-)-TetrahydrozolineCAS 84-22-0

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

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RFQ questions for CAS 64461-82-1

What are the key identifiers for Tizanidine Hydrochloride (CAS 64461-82-1)?

Tizanidine Hydrochloride is identified by CAS 64461-82-1, with molecular formula C9H9Cl2N5S, molecular weight 290.17, InChIKey ZWUKMNZJRDGCTQ-UHFFFAOYSA-N.

Does CAS 64461-82-1 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Alpha-2A adrenergic receptor, Adhesion G-protein coupled receptor F1, Apelin receptor, Beta-2 adrenergic receptor, C5a anaphylatoxin chemotactic receptor 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 64461-82-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Tizanidine Hydrochloride?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 64461-82-1 available for quotation?

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