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CAS Number: 649735-46-6
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CAS Number
649735-46-6
PubChem CID
11234052
Molecular Formula
C19H19FN4O3
Molecular Weight
370.4 g/mol
Exact Mass
370.144119
InChIKey
WCWUXEGQKLTGDX-LLVKDONJSA-N
IUPAC Name
(2R)-1-[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-ol
SMILES String
Cc1cc2c(F)c(Oc3ncnn4cc(OC[C@@H](C)O)c(C)c34)ccc2[nH]1
No physical property values available.
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Brivanib (CAS 649735-46-6) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C19H19FN4O3 and molecular weight 370. 40 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: Vascular endothelial growth factor receptor 2 (Homo sapiens) — 5 assays; Vascular endothelial growth factor receptor 1 (Homo sapiens) — 2 assays; Mast/stem cell growth factor receptor Kit (Homo sapiens) — 8 assays; Fibroblast growth factor receptor 1 (Homo sapiens) — 5 assays; Platelet-derived growth factor receptor beta (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Vascular endothelial growth factor receptor 2
Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 5 documents · best pChEMBL 8.3
Experimental evidence source: ChEMBL
Vascular endothelial growth factor receptor 1
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 8
Experimental evidence source: ChEMBL
Mast/stem cell growth factor receptor Kit
Homo sapiens · SINGLE PROTEIN · 8 qualifying assays · 1 documents · best pChEMBL 7.92
Experimental evidence source: ChEMBL
Fibroblast growth factor receptor 1
Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 5 documents · best pChEMBL 7.55
Experimental evidence source: ChEMBL
Platelet-derived growth factor receptor beta
Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 7.3
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
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Preliminary Safety Reference
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Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Brivanib is identified by CAS 649735-46-6, with molecular formula C19H19FN4O3, molecular weight 370.4, InChIKey WCWUXEGQKLTGDX-LLVKDONJSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Vascular endothelial growth factor receptor 2, Vascular endothelial growth factor receptor 1, Mast/stem cell growth factor receptor Kit, Fibroblast growth factor receptor 1, Platelet-derived growth factor receptor beta. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
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