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Home/Compounds/CAS 65646-68-6
Formula C26H33NO2MW 391.5Research-use catalog entryCOA/SDS by request

Fenretinide

CAS Number: 65646-68-6

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Loading RDKit molecule structure...
InChIKey: AKJHMTWEGVYYSE-FXILSDISSA-NC26H33NO2 | MW 391.5

Chemical Absolute Identifiers

CAS Number

65646-68-6

PubChem CID

5288209

Molecular Formula

C26H33NO2

Molecular Weight

391.5 g/mol

Exact Mass

391.251129

InChIKey

AKJHMTWEGVYYSE-FXILSDISSA-N

IUPAC Name

(2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenamide

SMILES String

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)Nc2ccc(O)cc2)C(C)(C)CCC1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Fenretinide (CAS 65646-68-6) is listed in the Advanced Chemicals portfolio, with molecular formula C26H33NO2 and molecular weight 391. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Natural Product ResearchSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Retinol-binding protein 4 (Homo sapiens) — 2 assays; Sphingolipid delta(4)-desaturase DES1 (Rattus norvegicus) — 2 assays; Nuclear receptor ROR-gamma (Mus musculus) — 2 assays; Nuclear factor NF-kappa-B p105 subunit (Homo sapiens) — 3 assays; Prosaposin (Homo sapiens) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Retinol-binding protein 4

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.81

Experimental evidence source: ChEMBL

Sphingolipid delta(4)-desaturase DES1

Rattus norvegicus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.63

Experimental evidence source: ChEMBL

Nuclear receptor ROR-gamma

Mus musculus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.35

Experimental evidence source: ChEMBL

Nuclear factor NF-kappa-B p105 subunit

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 5.2

Experimental evidence source: ChEMBL

Prosaposin

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents · best pChEMBL 5.16

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Fenretinide

Names & Synonyms

N-(4-Hydroxyphenyl)retinamide4-HPR4-hydroxyphenylretinamide4-Hydroxyphenyl retinamideall-trans-4'-Hydroxyretinanilide
Show all synonyms
FenretinidaMcN-R-1967FenretinidumRetinamide, N-(4-hydroxyphenyl)-N-(4-Hydroxyphenyl)all-Trans Retinamide4-hydroxy(phenyl)retinamideRii retinamide15-[(4-hydroxyphenyl)amino]retinalall-trans-n-(4-hydroxyphenyl)retinamideFenretinimide15-((4-hydroxyphenyl)amino)retinal4 Hydroxyphenylretinamide13-cis-Isomer FenretinideN-(4-Hydroxyphenyl)-trans-RetinamideMCN R 1967
External Identifiers
EC NUMBER: 636-255-5DSSTOX SUBSTANCE ID: DTXSID2032005CHEMBL ID: CHEMBL7301CHEBI ID: CHEBI:42588UNII: 187EJ7QEXLDRUGBANK ID: DB05076KEGG ID: D04162METABOLOMICS WORKBENCH ID: 56466NCI THESAURUS CODE: C1098WIKIDATA ID: Q5443576
Experimental Spectrum References
13C NMR SpectraFTIR Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2023.115416Perspectives on the current antiviral developments towards RNA-dependent RNA polymerase (RdRp) and methyltransferase (MTase) domains of dengue virus non-structural protein 5 (DENV-NS5).DOI 10.6019/EOS300108ECBD screening data for assay EOS300108PMID 37159959Perspectives on the current antiviral developments towards RNA-dependent RNA polymerase (RdRp) and methyltransferase (MTase) domains of dengue virus non-structural protein 5 (DENV-NS5).DOI 10.1016/j.ejmech.2021.113268Medulloblastoma drugs in development: Current leads, trials and drawbacks.DOI 10.1021/acs.jmedchem.0c01664Small Molecule Inhibitors Targeting Biosynthesis of Ceramide, the Central Hub of the Sphingolipid Network.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsPMID 33395289Small Molecule Inhibitors Targeting Biosynthesis of Ceramide, the Central Hub of the Sphingolipid Network.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Retinoic AcidCAS 302-79-4
Retinol PalmitateCAS 79-81-2
DemethoxycurcuminCAS 22608-11-3

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 302-79-4Retinoic AcidCAS 79-81-2Retinol PalmitateCAS 50-65-7NiclosamideCAS 21829-25-4NifedipineCAS 519-23-3EllipticineCAS 102767-28-2LevetiracetamCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 65646-68-6

What are the key identifiers for Fenretinide (CAS 65646-68-6)?

Fenretinide is identified by CAS 65646-68-6, with molecular formula C26H33NO2, molecular weight 391.5, InChIKey AKJHMTWEGVYYSE-FXILSDISSA-N.

Does CAS 65646-68-6 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Retinol-binding protein 4, Sphingolipid delta(4)-desaturase DES1, Nuclear receptor ROR-gamma, Nuclear factor NF-kappa-B p105 subunit, Prosaposin. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 65646-68-6?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Fenretinide?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 65646-68-6 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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