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Home/Compounds/CAS 66-22-8
Formula C4H4N2O2MW 112.09Research-use catalog entryCOA/SDS by request

Uracil

CAS Number: 66-22-8

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Available options

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1 kg
Purity
98%
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Loading RDKit molecule structure...
InChIKey: ISAKRJDGNUQOIC-UHFFFAOYSA-NC4H4N2O2 | MW 112.09

Chemical Absolute Identifiers

CAS Number

66-22-8

PubChem CID

1174

Molecular Formula

C4H4N2O2

Molecular Weight

112.09 g/mol

Exact Mass

112.027277

InChIKey

ISAKRJDGNUQOIC-UHFFFAOYSA-N

IUPAC Name

1H-pyrimidine-2,4-dione

SMILES String

Oc1ccnc(O)n1

Physical Properties

pKa

9.45

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Uracil (CAS 66-22-8) is listed in the Advanced Chemicals portfolio, with molecular formula C4H4N2O2 and molecular weight 112. 09 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Natural Product ResearchSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Uracil

Names & Synonyms

pyrimidine-2,4(1H,3H)-dione2,4(1H,3H)-PyrimidinedionePyrodHybar X2,4-Dioxopyrimidine
Show all synonyms
Pirod2,4-Pyrimidinedione1,2,3,4-tetrahydropyrimidine-2,4-dione2, 4-Dioxopyrimidine2-hydroxy-4-(1H)-pyrimidione2-hydroxy-4-(3H)-pyrimidione4-hydroxy-2-(1H)-pyrimidione2,4-Dihydroxypyrimidinepyrimidine-2,4-diol2,4-PyrimidinediolUracil [USAN]RU 127092-Hydroxy-4(3H)-pyrimidinoneUra
External Identifiers
EC NUMBER: 200-621-9DSSTOX SUBSTANCE ID: DTXSID4021424CHEMBL ID: CHEMBL566CHEBI ID: CHEBI:17568UNII: 56HH86ZVCTDRUGBANK ID: DB03419HMDB ID: HMDB0000300KEGG ID: C00106KEGG ID: D00027METABOLOMICS WORKBENCH ID: 37192NCI THESAURUS CODE: C917PHARMGKB ID: PA166342241WIKIDATA ID: Q182990
Experimental Spectrum References
13C NMR Spectra15N NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR SpectraRaman Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1016/j.ejmech.2023.115604Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment.DOI 10.1021/acs.jmedchem.2c01882E3 Ligases Meet Their Match: Fragment-Based Approaches to Discover New E3 Ligands and to Unravel E3 Biology.PMID 36821822E3 Ligases Meet Their Match: Fragment-Based Approaches to Discover New E3 Ligands and to Unravel E3 Biology.PMID 37399710Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment.DOI 10.1016/j.bmcl.2022.129008Identification of a new and diverse set of Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) inhibitors using structure-based virtual screening: Experimental validation and molecular dynamics studies.PMID 36174837Identification of a new and diverse set of Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) inhibitors using structure-based virtual screening: Experimental validation and molecular dynamics studies.DOI 10.1021/acsmedchemlett.0c00440Sweet and Blind Spots in E3 Ligase Ligand Space Revealed by a Thermophoresis-Based Assay.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activity

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

3-Hydroxypicolinic AcidCAS 874-24-8
PyrogallolCAS 87-66-1
pyridine-4-carboximidothioic acidCAS 2196-13-6

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 50-35-1ThalidomideCAS 100643-71-8DesloratadineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 66-22-8

What are the key identifiers for Uracil (CAS 66-22-8)?

Uracil is identified by CAS 66-22-8, with molecular formula C4H4N2O2, molecular weight 112.09, InChIKey ISAKRJDGNUQOIC-UHFFFAOYSA-N.

Does CAS 66-22-8 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 66-22-8?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Uracil?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 66-22-8 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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