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Home/Compounds/CAS 66-71-7
Formula C12H8N2MW 180.2Research-use catalog entryCOA/SDS by request

1,10-Phenanthroline

CAS Number: 66-71-7

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Loading RDKit molecule structure...
InChIKey: DGEZNRSVGBDHLK-UHFFFAOYSA-NC12H8N2 | MW 180.2

Chemical Absolute Identifiers

CAS Number

66-71-7

PubChem CID

1318

Molecular Formula

C12H8N2

Molecular Weight

180.2 g/mol

Exact Mass

180.068748

InChIKey

DGEZNRSVGBDHLK-UHFFFAOYSA-N

SMILES String

c1cnc2c(c1)ccc1cccnc12

Physical Properties

Melting Point

117.0 °C

Boiling Point

3.0 °C

pKa

4.27

Show more physical data

Vapor Pressure

Estimated very low; unit not specified

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

1,10-Phenanthroline (CAS 66-71-7) is listed in the Catalysts and Ligands portfolio, with molecular formula C12H8N2 and molecular weight 180. 20 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for catalysis development, ligand screening, and synthetic method research; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Asymmetric SynthesisCatalysis and Ligand ResearchLigand ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Serine/threonine-protein kinase mTOR (Homo sapiens) — 2 assays; Thrombopoietin (Homo sapiens) — 2 assays; Cellular tumor antigen p53 (Homo sapiens) — 3 assays; Thyrotropin receptor (Homo sapiens) — 2 assays; Collagenase 3 (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Serine/threonine-protein kinase mTOR

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 7.33

Experimental evidence source: ChEMBL

Thrombopoietin

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.6

Experimental evidence source: ChEMBL

Cellular tumor antigen p53

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 5.5

Experimental evidence source: ChEMBL

Thyrotropin receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.5

Experimental evidence source: ChEMBL

Collagenase 3

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 5.4

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

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Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

1,10-Phenanthroline

Names & Synonyms

o-phenanthroline4,5-diazaphenanthreneorthophenanthroline1,10-o-phenanthrolinebeta-phenanthroline
Show all synonyms
2-phenanthrolineO-PHE(OP)2Cu(I)Phenanthroline1,10-Phenanthroline anhydrous1,10-Fenanthrolin.beta.-Phenanthroline[1,10]phenanthrolinephenpyridino[3,2-h]quinolinePHN1,10-Fenanthrolin [Czech]CCRIS 48551,10-Phenanthroline, Anhydrous
External Identifiers
EC NUMBER: 200-629-2DSSTOX SUBSTANCE ID: DTXSID1025857CHEMBL ID: CHEMBL415879CHEBI ID: CHEBI:44975UNII: W4X6ZO7939DRUGBANK ID: DB02365HMDB ID: HMDB0244053KEGG ID: C00604METABOLOMICS WORKBENCH ID: 52403RXCUI: 1872047WIKIDATA ID: Q416005Activ-8
Experimental Spectrum References
13C NMR Spectra15N NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR Spectra — Bio-Rad Laboratories, Inc.FTIR Spectra — Bio-Rad Laboratories, Inc.Raman Spectra — Bio-Rad LaboratoriesUV-VIS Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2021.113975Nitroxoline and its derivatives are potent inhibitors of metallo-β-lactamases.PMID 34865870Nitroxoline and its derivatives are potent inhibitors of metallo-β-lactamases.DOI 10.1016/j.bmc.2021.116467In vitro activity of N-phenyl-1,10-phenanthroline-2-amines against tachyzoites and bradyzoites of Toxoplasma gondii.DOI 10.1039/d0md00320dIdentification of 3-hydroxy-1,2-dimethylpyridine-4(1H)-thione as a metal-binding motif for the inhibition of botulinum neurotoxin APMID 34046606Identification of 3-hydroxy-1,2-dimethylpyridine-4(1H)-thione as a metal-binding motif for the inhibition of botulinum neurotoxin APMID 34666274In vitro activity of N-phenyl-1,10-phenanthroline-2-amines against tachyzoites and bradyzoites of Toxoplasma gondii.DOI 10.1021/acs.jmedchem.7b00407Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase-1.DOI 10.1021/acsmedchemlett.7b00186Structure-Based Discovery of Thiosemicarbazone Metalloproteinase Inhibitors for Hemorrhage Treatment in Snakebites.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

1,10-Phenanthroline hydrateCAS 5144-89-8
1,10-Phenanthroline hydrochlorideCAS 3829-86-5
1,10-Phenanthroline monohydrochloride monohydrateCAS 18851-33-7
Dichlororuthenium--1,10-phenanthroline--water (1/3/1)CAS 207802-45-7
2-Chloro-1,10-phenanthrolineCAS 7089-68-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 5144-89-81,10-Phenanthroline hydrateCAS 3829-86-51,10-Phenanthroline hydrochlorideCAS 18851-33-71,10-Phenanthroline monohydrochloride monohydrateCAS 207802-45-7Dichlororuthenium--1,10-phenanthroline--water (1/3/1)CAS 7089-68-12-Chloro-1,10-phenanthrolineCAS 50-65-7NiclosamideCAS 519-23-3EllipticineCAS 65646-68-6FenretinideCAS 1148-79-42,2':6',2''-TerpyridineCAS 130-16-55-Chloro-8-hydroxyquinoline

RFQ questions for CAS 66-71-7

What are the key identifiers for 1,10-Phenanthroline (CAS 66-71-7)?

1,10-Phenanthroline is identified by CAS 66-71-7, with molecular formula C12H8N2, molecular weight 180.2, InChIKey DGEZNRSVGBDHLK-UHFFFAOYSA-N.

Does CAS 66-71-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Serine/threonine-protein kinase mTOR, Thrombopoietin, Cellular tumor antigen p53, Thyrotropin receptor, Collagenase 3. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 66-71-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 1,10-Phenanthroline?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 66-71-7 available for quotation?

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