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- 1 g
- Purity
- 99%
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CAS Number: 668270-12-0
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CAS Number
668270-12-0
PubChem CID
10096344
Molecular Formula
C25H28N8O2
Molecular Weight
472.5 g/mol
Exact Mass
472.233522
InChIKey
LTXREWYXXSTFRX-QGZVFWFLSA-N
IUPAC Name
8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione
SMILES String
CC#CCn1c(N2CCC[C@@H](N)C2)nc2c1c(=O)n(Cc1nc(C)c3ccccc3n1)c(=O)n2C
Melting Point
202.0 °C
Water Solubility
1 mol/L
pKa
1
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Linagliptin (CAS 668270-12-0) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C25H28N8O2 and molecular weight 472. 50 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: Dipeptidyl peptidase 4 (Homo sapiens) — 34 assays; Prolyl endopeptidase FAP (Homo sapiens) — 7 assays; Muscarinic acetylcholine receptor M1 (Homo sapiens) — 4 assays; Prolyl endopeptidase FAP (Mus musculus) — 2 assays; Histamine H2 receptor (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Dipeptidyl peptidase 4
Homo sapiens · SINGLE PROTEIN · 34 qualifying assays · 25 documents · best pChEMBL 10
Experimental evidence source: ChEMBL
Prolyl endopeptidase FAP
Homo sapiens · SINGLE PROTEIN · 7 qualifying assays · 4 documents · best pChEMBL 7.15
Experimental evidence source: ChEMBL
Muscarinic acetylcholine receptor M1
Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 4 documents · best pChEMBL 6.53
Experimental evidence source: ChEMBL
Prolyl endopeptidase FAP
Mus musculus · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.43
Experimental evidence source: ChEMBL
Histamine H2 receptor
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.91
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
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Preliminary Safety Reference
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Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Linagliptin is identified by CAS 668270-12-0, with molecular formula C25H28N8O2, molecular weight 472.5, InChIKey LTXREWYXXSTFRX-QGZVFWFLSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Dipeptidyl peptidase 4, Prolyl endopeptidase FAP, Muscarinic acetylcholine receptor M1, Prolyl endopeptidase FAP, Histamine H2 receptor. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
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