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- Purity
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CAS Number: 670220-88-9
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CAS Number
670220-88-9
PubChem CID
10366136
Molecular Formula
C26H29N5O2
Molecular Weight
443.5 g/mol
Exact Mass
443.232125
InChIKey
DYNHJHQFHQTFTP-UHFFFAOYSA-N
IUPAC Name
1-[2-[5-[(3-methyloxetan-3-yl)methoxy]benzimidazol-1-yl]quinolin-8-yl]piperidin-4-amine
SMILES String
CC1(COc2ccc3c(c2)ncn3-c2ccc3cccc(N4CCC(N)CC4)c3n2)COC1
No physical property values available.
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Crenolanib (CAS 670220-88-9) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C26H29N5O2 and molecular weight 443. 50 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens) — 37 assays; Interleukin-1 receptor-associated kinase 4 (Homo sapiens) — 2 assays; Interleukin-1 receptor-associated kinase 1 (Homo sapiens) — 2 assays; Platelet-derived growth factor receptor (Homo sapiens) — 6 assays; Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Receptor-type tyrosine-protein kinase FLT3
Homo sapiens · SINGLE PROTEIN · 37 qualifying assays · 11 documents · best pChEMBL 10.8
Experimental evidence source: ChEMBL
Interleukin-1 receptor-associated kinase 4
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 7.21
Experimental evidence source: ChEMBL
Interleukin-1 receptor-associated kinase 1
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.58
Experimental evidence source: ChEMBL
Platelet-derived growth factor receptor
Homo sapiens · PROTEIN COMPLEX · 6 qualifying assays · 1 documents · best pChEMBL 5.78
Experimental evidence source: ChEMBL
Protein deacetylase HDAC6
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
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Preliminary Safety Reference
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Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Crenolanib is identified by CAS 670220-88-9, with molecular formula C26H29N5O2, molecular weight 443.5, InChIKey DYNHJHQFHQTFTP-UHFFFAOYSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Receptor-type tyrosine-protein kinase FLT3, Interleukin-1 receptor-associated kinase 4, Interleukin-1 receptor-associated kinase 1, Platelet-derived growth factor receptor, Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
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