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Home/Compounds/CAS 68291-97-4
Formula C8H8N2O3SMW 212.23Research-use catalog entryCOA/SDS by request

Zonisamide

CAS Number: 68291-97-4

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Loading RDKit molecule structure...
InChIKey: UBQNRHZMVUUOMG-UHFFFAOYSA-NC8H8N2O3S | MW 212.23

Chemical Absolute Identifiers

CAS Number

68291-97-4

PubChem CID

5734

Molecular Formula

C8H8N2O3S

Molecular Weight

212.23 g/mol

Exact Mass

212.025563

InChIKey

UBQNRHZMVUUOMG-UHFFFAOYSA-N

IUPAC Name

1,2-benzoxazol-3-ylmethanesulfonamide

SMILES String

C1=CC=C2C(=C1)C(=NO2)CS(=O)(=O)N

Physical Properties

Melting Point

16–163 °C

pKa

10.2

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Zonisamide (CAS 68291-97-4) is listed in the Advanced Chemicals portfolio, with molecular formula C8H8N2O3S and molecular weight 212. 23 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Carbonic anhydrase 7 (Homo sapiens) — 11 assays; Carbonic anhydrase 12 (Homo sapiens) — 7 assays; Carbonic anhydrase 9 (Homo sapiens) — 12 assays; Carbonic anhydrase 2 (Homo sapiens) — 65 assays; Carbonic anhydrase 5A, mitochondrial (Homo sapiens) — 7 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Carbonic anhydrase 7

Homo sapiens · SINGLE PROTEIN · 11 qualifying assays · 11 documents · best pChEMBL 9.05

Experimental evidence source: ChEMBL

Carbonic anhydrase 12

Homo sapiens · SINGLE PROTEIN · 7 qualifying assays · 7 documents · best pChEMBL 8.42

Experimental evidence source: ChEMBL

Carbonic anhydrase 9

Homo sapiens · SINGLE PROTEIN · 12 qualifying assays · 12 documents · best pChEMBL 8.3

Experimental evidence source: ChEMBL

Carbonic anhydrase 2

Homo sapiens · SINGLE PROTEIN · 65 qualifying assays · 63 documents · best pChEMBL 7.99

Experimental evidence source: ChEMBL

Carbonic anhydrase 5A, mitochondrial

Homo sapiens · SINGLE PROTEIN · 7 qualifying assays · 7 documents · best pChEMBL 7.7

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.
  • Avoid contact with skin and eyes.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • and reactivity.
  • Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional institution with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Zonisamide

Names & Synonyms

Zonegran1,2-Benzisoxazole-3-methanesulfonamideExceglanExcegramExcegran
Show all synonyms
ZonisamidaZonisamidum3-(Sulfamoylmethyl)-1,2-benzisoxazoleZONISADEBenzo[d]isoxazol-3-yl-methanesulfonamide1,2-Benzisoxazol-3-ylmethanesulfonamideBenzo(d)isoxazol-3-yl-methanesulfonamideAD810CI9123 Sulfamoylmethyl 1,2 benzisoxazolebenzo[d]isoxazol-3-ylmethanesulfonamideZonisamidum [Latin]Zonisamida [Spanish]AD 810
External Identifiers
EC NUMBER: 614-395-8DSSTOX SUBSTANCE ID: DTXSID9046023CHEMBL ID: CHEMBL750CHEBI ID: CHEBI:10127UNII: 459384H98VDRUGBANK ID: DB00909HMDB ID: HMDB0015045KEGG ID: C07504KEGG ID: D00538METABOLOMICS WORKBENCH ID: 43178NCI THESAURUS CODE: C47790PHARMGKB ID: PA451978RXCUI: 39998
Literature & Patent References
DOI 10.1021/acs.jmedchem.5c00526Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors.PMID 40237575Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors.DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1021/acs.jmedchem.4c01512Investigating Active Site Binding of Ligands to High and Low Activity Carbonic Anhydrase Enzymes Using Native Mass Spectrometry.PMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 39161321Investigating Active Site Binding of Ligands to High and Low Activity Carbonic Anhydrase Enzymes Using Native Mass Spectrometry.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

sodium 1,2-benzoxazol-3-ylmethanesulfonateCAS 73101-64-1
1,2-Benzisoxazole, 3-(bromomethyl)-CAS 37924-85-9
2-(1,2-Benzoxazol-3-yl)acetic acidCAS 4865-84-3
3-(2-Bromo-ethyl)-benzo[d]isoxazoleCAS 57148-67-1
1,2-Benzoxazol-3-amineCAS 36216-80-5

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 97240-79-4TopiramateCAS 73101-64-1sodium 1,2-benzoxazol-3-ylmethanesulfonateCAS 37924-85-91,2-Benzisoxazole, 3-(bromomethyl)-CAS 4865-84-32-(1,2-Benzoxazol-3-yl)acetic acidCAS 57148-67-13-(2-Bromo-ethyl)-benzo[d]isoxazoleCAS 36216-80-51,2-Benzoxazol-3-amineCAS 169590-42-5CelecoxibCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 68291-97-4

What are the key identifiers for Zonisamide (CAS 68291-97-4)?

Zonisamide is identified by CAS 68291-97-4, with molecular formula C8H8N2O3S, molecular weight 212.23, InChIKey UBQNRHZMVUUOMG-UHFFFAOYSA-N.

Does CAS 68291-97-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Carbonic anhydrase 7, Carbonic anhydrase 12, Carbonic anhydrase 9, Carbonic anhydrase 2, Carbonic anhydrase 5A, mitochondrial. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 68291-97-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Zonisamide?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 68291-97-4 available for quotation?

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